CLDND1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	25 studies	29% ± 11%	Explore
CD8-positive, alpha-beta T cell	23 studies	31% ± 17%	Explore
regulatory T cell	22 studies	32% ± 17%	Explore
CD4-positive, alpha-beta T cell	21 studies	27% ± 17%	Explore
endothelial cell	21 studies	24% ± 9%	Explore
oligodendrocyte	17 studies	54% ± 21%	Explore
pericyte	17 studies	22% ± 6%	Explore
T cell	15 studies	24% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	33% ± 12%	Explore
fibroblast	15 studies	23% ± 8%	Explore
gamma-delta T cell	13 studies	26% ± 10%	Explore
smooth muscle cell	12 studies	23% ± 5%	Explore
mucosal invariant T cell	11 studies	23% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	34% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	21% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	34% ± 24%	Explore
connective tissue cell	9 studies	21% ± 5%	Explore
basal cell	9 studies	25% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	30% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	31% ± 9%	Explore
capillary endothelial cell	8 studies	17% ± 2%	Explore
endothelial cell of vascular tree	8 studies	19% ± 4%	Explore
epithelial cell	7 studies	33% ± 15%	Explore
oligodendrocyte precursor cell	7 studies	25% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	41% ± 22%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	20% ± 3%	Explore
mature NK T cell	6 studies	29% ± 6%	Explore
innate lymphoid cell	6 studies	27% ± 9%	Explore
astrocyte	6 studies	22% ± 5%	Explore
endothelial cell of artery	6 studies	19% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	37% ± 22%	Explore
endothelial cell of lymphatic vessel	6 studies	20% ± 5%	Explore
exhausted T cell	5 studies	48% ± 21%	Explore
B cell	5 studies	19% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	46% ± 33%	Explore
plasma cell	4 studies	27% ± 11%	Explore
plasmablast	4 studies	39% ± 16%	Explore
leukocyte	4 studies	20% ± 2%	Explore
conventional dendritic cell	4 studies	26% ± 8%	Explore
myofibroblast cell	4 studies	27% ± 4%	Explore
neuron	4 studies	38% ± 15%	Explore
macrophage	4 studies	18% ± 3%	Explore
T follicular helper cell	4 studies	18% ± 2%	Explore
secretory cell	4 studies	23% ± 2%	Explore
double negative thymocyte	4 studies	23% ± 7%	Explore
classical monocyte	3 studies	22% ± 5%	Explore
non-classical monocyte	3 studies	22% ± 4%	Explore
glomerular endothelial cell	3 studies	19% ± 1%	Explore
extravillous trophoblast	3 studies	27% ± 7%	Explore
ciliated cell	3 studies	24% ± 0%	Explore
lymphocyte	3 studies	30% ± 10%	Explore
intraepithelial lymphocyte	3 studies	26% ± 2%	Explore
CD4-positive helper T cell	3 studies	25% ± 6%	Explore
vein endothelial cell	3 studies	17% ± 1%	Explore
GABAergic neuron	3 studies	36% ± 4%	Explore
glutamatergic neuron	3 studies	46% ± 2%	Explore
T-helper 17 cell	3 studies	47% ± 23%	Explore
plasmacytoid dendritic cell	3 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	20% ± 1%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	24% ± 7%	Explore
microglial cell	3 studies	21% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	10 studies	33% ± 15%	Explore
peripheral blood	7 studies	22% ± 4%	Explore
lung	7 studies	24% ± 5%	Explore
eye	4 studies	18% ± 2%	Explore
intestine	4 studies	22% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	21034.25	2642 / 2642	100%	139.85	705 / 705
esophagus	100%	4826.80	1445 / 1445	100%	53.70	183 / 183
ovary	100%	4610.24	180 / 180	100%	30.88	430 / 430
lung	100%	4173.63	576 / 578	100%	51.06	1155 / 1155
breast	100%	3747.14	459 / 459	99%	31.59	1110 / 1118
bladder	100%	3938.71	21 / 21	99%	34.94	500 / 504
prostate	100%	3537.92	244 / 245	100%	30.48	500 / 502
uterus	100%	4623.42	170 / 170	99%	52.51	455 / 459
thymus	100%	3470.31	651 / 653	99%	26.89	598 / 605
intestine	100%	4226.07	966 / 966	98%	24.97	515 / 527
skin	100%	4602.72	1807 / 1809	96%	35.92	455 / 472
adrenal gland	100%	2109.31	257 / 258	97%	29.02	222 / 230
stomach	97%	2628.84	347 / 359	98%	24.91	281 / 286
kidney	98%	2402.90	87 / 89	96%	28.77	866 / 901
liver	88%	1382.52	200 / 226	88%	13.70	356 / 406
pancreas	60%	863.57	197 / 328	98%	30.51	175 / 178
spleen	100%	3467.34	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	63.58	45 / 45
ureter	0%	0	0 / 0	100%	12.86	1 / 1
blood vessel	100%	4654.95	1333 / 1335	0%	0	0 / 0
adipose	100%	3886.99	1201 / 1204	0%	0	0 / 0
heart	97%	2540.55	831 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	23.70	27 / 29
muscle	92%	1701.49	739 / 803	0%	0	0 / 0
peripheral blood	76%	2676.88	704 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	70%	11.36	56 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0