CDV3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
macrophage	26 studies	31% ± 16%	Explore
endothelial cell	23 studies	30% ± 13%	Explore
B cell	21 studies	33% ± 13%	Explore
classical monocyte	17 studies	36% ± 21%	Explore
natural killer cell	16 studies	29% ± 13%	Explore
fibroblast	16 studies	33% ± 17%	Explore
conventional dendritic cell	16 studies	32% ± 19%	Explore
non-classical monocyte	15 studies	37% ± 24%	Explore
plasma cell	13 studies	36% ± 15%	Explore
CD8-positive, alpha-beta T cell	13 studies	28% ± 12%	Explore
epithelial cell	12 studies	39% ± 22%	Explore
basal cell	12 studies	30% ± 11%	Explore
regulatory T cell	12 studies	29% ± 13%	Explore
T cell	11 studies	27% ± 16%	Explore
smooth muscle cell	11 studies	32% ± 9%	Explore
memory B cell	11 studies	25% ± 8%	Explore
plasmacytoid dendritic cell	11 studies	32% ± 14%	Explore
CD4-positive, alpha-beta T cell	11 studies	30% ± 14%	Explore
dendritic cell	10 studies	45% ± 27%	Explore
pericyte	10 studies	34% ± 14%	Explore
gamma-delta T cell	10 studies	33% ± 17%	Explore
naive B cell	9 studies	26% ± 10%	Explore
myeloid cell	9 studies	40% ± 20%	Explore
endothelial cell of vascular tree	9 studies	31% ± 14%	Explore
monocyte	8 studies	37% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	31% ± 16%	Explore
leukocyte	8 studies	34% ± 14%	Explore
vein endothelial cell	8 studies	21% ± 11%	Explore
alveolar macrophage	7 studies	25% ± 10%	Explore
mast cell	7 studies	36% ± 10%	Explore
endothelial cell of lymphatic vessel	7 studies	42% ± 20%	Explore
plasmablast	7 studies	53% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	32% ± 15%	Explore
endothelial cell of artery	7 studies	23% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	36% ± 14%	Explore
mononuclear phagocyte	6 studies	28% ± 11%	Explore
abnormal cell	6 studies	22% ± 4%	Explore
ciliated cell	6 studies	33% ± 20%	Explore
secretory cell	6 studies	32% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	33% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	31% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	33% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	47% ± 5%	Explore
IgA plasma cell	5 studies	25% ± 6%	Explore
T follicular helper cell	5 studies	24% ± 10%	Explore
mucosal invariant T cell	5 studies	26% ± 7%	Explore
type I pneumocyte	4 studies	39% ± 12%	Explore
pancreatic A cell	4 studies	34% ± 8%	Explore
hematopoietic precursor cell	4 studies	37% ± 16%	Explore
mature NK T cell	4 studies	38% ± 10%	Explore
IgG plasma cell	4 studies	22% ± 2%	Explore
microglial cell	4 studies	29% ± 9%	Explore
type II pneumocyte	3 studies	30% ± 6%	Explore
type B pancreatic cell	3 studies	45% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	31% ± 13%	Explore
tissue-resident macrophage	3 studies	31% ± 18%	Explore
germinal center B cell	3 studies	31% ± 2%	Explore
CD4-positive helper T cell	3 studies	42% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	50% ± 10%	Explore
innate lymphoid cell	3 studies	32% ± 10%	Explore
neuron	3 studies	25% ± 6%	Explore
luminal cell of prostate epithelium	3 studies	26% ± 9%	Explore
GABAergic neuron	3 studies	25% ± 7%	Explore
glutamatergic neuron	3 studies	35% ± 10%	Explore
pancreatic ductal cell	3 studies	45% ± 13%	Explore
connective tissue cell	3 studies	35% ± 7%	Explore
neutrophil	3 studies	22% ± 4%	Explore
goblet cell	3 studies	24% ± 1%	Explore
transit amplifying cell	3 studies	23% ± 6%	Explore
T-helper 17 cell	3 studies	28% ± 5%	Explore
erythroblast	3 studies	33% ± 13%	Explore
double negative thymocyte	3 studies	32% ± 7%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	9 studies	30% ± 16%	Explore
peripheral blood	9 studies	38% ± 18%	Explore
intestine	7 studies	22% ± 5%	Explore
brain	5 studies	25% ± 5%	Explore
liver	5 studies	27% ± 10%	Explore
pancreas	4 studies	35% ± 13%	Explore
uterus	4 studies	37% ± 16%	Explore
bone marrow	3 studies	36% ± 7%	Explore
eye	3 studies	21% ± 4%	Explore
breast	3 studies	28% ± 12%	Explore
prostate	3 studies	32% ± 8%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	9270.76	1445 / 1445	100%	141.20	183 / 183
lung	100%	10821.79	578 / 578	100%	142.73	1155 / 1155
stomach	100%	7981.62	359 / 359	100%	118.15	286 / 286
breast	100%	10140.78	459 / 459	100%	182.75	1117 / 1118
intestine	100%	9299.98	966 / 966	100%	131.69	526 / 527
uterus	100%	7380.31	170 / 170	100%	144.51	458 / 459
pancreas	100%	5782.12	327 / 328	100%	117.89	178 / 178
thymus	100%	9276.26	653 / 653	100%	143.59	603 / 605
ovary	100%	7377.19	180 / 180	100%	93.00	428 / 430
skin	100%	10227.24	1808 / 1809	100%	133.60	470 / 472
prostate	100%	5714.35	244 / 245	99%	80.64	498 / 502
liver	100%	5218.74	226 / 226	99%	83.53	401 / 406
bladder	100%	9044.62	21 / 21	99%	113.70	497 / 504
brain	99%	4330.05	2605 / 2642	100%	114.03	705 / 705
kidney	100%	6986.76	89 / 89	98%	99.09	883 / 901
adrenal gland	100%	8078.04	258 / 258	93%	68.12	214 / 230
adipose	100%	12121.39	1204 / 1204	0%	0	0 / 0
blood vessel	100%	8762.24	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	80.69	80 / 80
lymph node	0%	0	0 / 0	100%	268.88	29 / 29
muscle	100%	19837.84	803 / 803	0%	0	0 / 0
spleen	100%	12899.67	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	153.94	45 / 45
ureter	0%	0	0 / 0	100%	41.68	1 / 1
heart	97%	6566.91	832 / 861	0%	0	0 / 0
peripheral blood	96%	8978.73	891 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0