CCSER2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	29 studies	33% ± 14%	Explore
natural killer cell	26 studies	27% ± 9%	Explore
CD8-positive, alpha-beta T cell	23 studies	25% ± 7%	Explore
CD4-positive, alpha-beta T cell	21 studies	25% ± 9%	Explore
T cell	20 studies	26% ± 10%	Explore
astrocyte	20 studies	37% ± 18%	Explore
fibroblast	17 studies	28% ± 8%	Explore
smooth muscle cell	17 studies	22% ± 7%	Explore
oligodendrocyte	16 studies	40% ± 16%	Explore
oligodendrocyte precursor cell	15 studies	39% ± 18%	Explore
mucosal invariant T cell	14 studies	25% ± 8%	Explore
endothelial cell of lymphatic vessel	13 studies	25% ± 8%	Explore
glutamatergic neuron	13 studies	47% ± 25%	Explore
mature NK T cell	13 studies	24% ± 7%	Explore
gamma-delta T cell	13 studies	27% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	27% ± 7%	Explore
microglial cell	12 studies	35% ± 13%	Explore
GABAergic neuron	11 studies	46% ± 22%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	28% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	30% ± 10%	Explore
regulatory T cell	11 studies	22% ± 4%	Explore
pericyte	10 studies	28% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	33% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	28% ± 7%	Explore
type I pneumocyte	8 studies	25% ± 8%	Explore
neuron	8 studies	43% ± 17%	Explore
macrophage	8 studies	32% ± 11%	Explore
adipocyte	8 studies	31% ± 8%	Explore
endothelial cell of artery	8 studies	27% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	22% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	28% ± 11%	Explore
epithelial cell	7 studies	35% ± 14%	Explore
retinal ganglion cell	7 studies	67% ± 24%	Explore
amacrine cell	7 studies	34% ± 11%	Explore
retinal cone cell	7 studies	24% ± 9%	Explore
interneuron	6 studies	55% ± 22%	Explore
myofibroblast cell	6 studies	24% ± 6%	Explore
myeloid cell	6 studies	21% ± 5%	Explore
retina horizontal cell	6 studies	33% ± 10%	Explore
retinal rod cell	6 studies	27% ± 8%	Explore
dendritic cell	6 studies	23% ± 5%	Explore
Mueller cell	6 studies	25% ± 8%	Explore
endothelial cell of vascular tree	6 studies	23% ± 13%	Explore
type II pneumocyte	6 studies	34% ± 6%	Explore
retinal bipolar neuron	5 studies	42% ± 14%	Explore
cardiac muscle cell	5 studies	44% ± 8%	Explore
ciliated cell	5 studies	22% ± 6%	Explore
lymphocyte	5 studies	41% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	24% ± 10%	Explore
connective tissue cell	5 studies	24% ± 8%	Explore
club cell	5 studies	30% ± 12%	Explore
basal cell	5 studies	27% ± 13%	Explore
leukocyte	4 studies	39% ± 12%	Explore
granule cell	4 studies	40% ± 5%	Explore
retinal pigment epithelial cell	4 studies	30% ± 18%	Explore
OFF-bipolar cell	4 studies	39% ± 20%	Explore
ON-bipolar cell	4 studies	57% ± 17%	Explore
innate lymphoid cell	4 studies	22% ± 9%	Explore
monocyte	4 studies	25% ± 3%	Explore
capillary endothelial cell	4 studies	28% ± 12%	Explore
T follicular helper cell	4 studies	24% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	28% ± 10%	Explore
double negative thymocyte	4 studies	28% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	23% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	29% ± 9%	Explore
exhausted T cell	3 studies	27% ± 7%	Explore
GABAergic interneuron	3 studies	41% ± 7%	Explore
glial cell	3 studies	28% ± 4%	Explore
progenitor cell	3 studies	42% ± 17%	Explore
mesothelial cell	3 studies	31% ± 12%	Explore
vein endothelial cell	3 studies	23% ± 9%	Explore
GABAergic amacrine cell	3 studies	39% ± 9%	Explore
glycinergic amacrine cell	3 studies	30% ± 2%	Explore
rod bipolar cell	3 studies	64% ± 14%	Explore
hepatocyte	3 studies	40% ± 17%	Explore
abnormal cell	3 studies	28% ± 14%	Explore
neural progenitor cell	3 studies	26% ± 6%	Explore
ependymal cell	3 studies	41% ± 18%	Explore
adventitial cell	3 studies	21% ± 3%	Explore
alveolar macrophage	3 studies	24% ± 7%	Explore
respiratory goblet cell	3 studies	29% ± 15%	Explore
goblet cell	3 studies	33% ± 14%	Explore
T-helper 17 cell	3 studies	20% ± 5%	Explore
mural cell	3 studies	50% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	44% ± 21%	Explore
lung	11 studies	21% ± 6%	Explore
eye	9 studies	32% ± 11%	Explore
peripheral blood	6 studies	22% ± 5%	Explore
heart	4 studies	32% ± 6%	Explore
kidney	4 studies	19% ± 2%	Explore
liver	4 studies	25% ± 13%	Explore
intestine	3 studies	18% ± 2%	Explore
adipose	3 studies	30% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3841.10	1445 / 1445	100%	23.52	183 / 183
brain	100%	4300.93	2637 / 2642	100%	41.40	705 / 705
lung	100%	4113.17	578 / 578	100%	20.60	1152 / 1155
thymus	100%	3691.29	653 / 653	100%	22.85	603 / 605
breast	100%	3117.48	459 / 459	100%	25.33	1114 / 1118
prostate	100%	3107.92	244 / 245	100%	17.48	500 / 502
uterus	100%	3815.83	170 / 170	99%	14.97	454 / 459
intestine	100%	4585.89	966 / 966	98%	17.61	518 / 527
kidney	100%	2061.85	89 / 89	98%	18.77	884 / 901
bladder	100%	3956.62	21 / 21	98%	15.64	494 / 504
adrenal gland	100%	2157.94	258 / 258	98%	20.53	225 / 230
ovary	100%	2915.36	180 / 180	97%	10.34	419 / 430
stomach	99%	2504.58	357 / 359	98%	18.71	280 / 286
skin	100%	3774.74	1808 / 1809	96%	17.95	454 / 472
pancreas	82%	983.73	268 / 328	99%	15.98	177 / 178
liver	92%	1139.11	207 / 226	89%	8.42	360 / 406
adipose	100%	3498.96	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5333.48	1335 / 1335	0%	0	0 / 0
muscle	100%	6669.56	803 / 803	0%	0	0 / 0
spleen	100%	1960.06	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	10.20	1 / 1
tonsil	0%	0	0 / 0	98%	16.51	44 / 45
heart	97%	5097.74	836 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	13.87	76 / 80
lymph node	0%	0	0 / 0	86%	12.29	25 / 29
peripheral blood	71%	1357.03	659 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	CCSER2
Protein name	Coiled-coil serine rich protein 2 Serine-rich coiled-coil domain-containing protein 2 (Coiled-coil serine-rich protein 2) (Protein GCAP14 homolog)
Synonyms	KIAA1128 NPD012 FAM190B
Description	FUNCTION: Microtubule-binding protein which might play a role in microtubule bundling. .
Accessions	ENST00000493409.5 ENST00000466105.5 ENST00000543283.2 [Q9H7U1-4] ENST00000359979.8 [Q9H7U1-2] ENST00000494586.5 A0A2R8Y7M2 A0A2R8Y6V5 ENST00000480006.1 A0A2R8YGE2 A0A2R8YGU6 ENST00000224756.12 [Q9H7U1-1] Q9H7U1 ENST00000372088.8 [Q9H7U1-3]

GO_0001578	Biological process	microtubule bundle formation
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0005737	Cellular component	cytoplasm
GO_0008017	Molecular function	microtubule binding

CCSER2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review