CAMK1D report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032793Biological processpositive regulation of CREB transcription factor activity
GO_0018105Biological processpeptidyl-serine phosphorylation
GO_0050766Biological processpositive regulation of phagocytosis
GO_0006954Biological processinflammatory response
GO_0010976Biological processpositive regulation of neuron projection development
GO_0071622Biological processregulation of granulocyte chemotaxis
GO_0050773Biological processregulation of dendrite development
GO_0043066Biological processnegative regulation of apoptotic process
GO_0090023Biological processpositive regulation of neutrophil chemotaxis
GO_0043065Biological processpositive regulation of apoptotic process
GO_0060267Biological processpositive regulation of respiratory burst
GO_0007399Biological processnervous system development
GO_0005622Cellular componentintracellular anatomical structure
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0106310Molecular functionprotein serine kinase activity
GO_0005524Molecular functionATP binding
GO_0004683Molecular functioncalmodulin-dependent protein kinase activity
GO_0005516Molecular functioncalmodulin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCAMK1D
Protein nameCalcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)
Calcium/calmodulin-dependent protein kinase ID, isoform CRA_b (Calcium/calmodulin-dependent protein kinase type 1D variant 2) (Calcium/calmodulin-dependent protein kinase type 1D variant 3) (cDNA FLJ76987, highly similar to Homo sapiens calcium/calmodulin-dependent protein kinase ID (CAMK1D), transcript variant 1, mRNA)
SynonymsCAMKID
hCG_1811212
DescriptionFUNCTION: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta. .

AccessionsENST00000378845.5 [Q8IU85-2]
ENST00000619168.5 [Q8IU85-1]
Q8IU85
Q5SQQ7