CAB39 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	22 studies	31% ± 17%	Explore
endothelial cell	20 studies	27% ± 10%	Explore
microglial cell	12 studies	41% ± 17%	Explore
glutamatergic neuron	11 studies	38% ± 25%	Explore
T cell	9 studies	26% ± 7%	Explore
type I pneumocyte	9 studies	28% ± 12%	Explore
ciliated cell	9 studies	27% ± 8%	Explore
oligodendrocyte precursor cell	9 studies	27% ± 12%	Explore
myeloid cell	9 studies	36% ± 15%	Explore
epithelial cell	9 studies	33% ± 17%	Explore
fibroblast	9 studies	21% ± 5%	Explore
astrocyte	9 studies	28% ± 13%	Explore
oligodendrocyte	9 studies	25% ± 9%	Explore
GABAergic neuron	8 studies	38% ± 21%	Explore
adipocyte	8 studies	23% ± 6%	Explore
classical monocyte	7 studies	25% ± 7%	Explore
neuron	7 studies	33% ± 15%	Explore
monocyte	7 studies	41% ± 13%	Explore
natural killer cell	6 studies	20% ± 4%	Explore
basal cell	6 studies	29% ± 19%	Explore
retinal cone cell	6 studies	26% ± 6%	Explore
dendritic cell	6 studies	35% ± 8%	Explore
interneuron	5 studies	39% ± 22%	Explore
club cell	5 studies	23% ± 8%	Explore
CD8-positive, alpha-beta T cell	5 studies	21% ± 4%	Explore
mast cell	5 studies	28% ± 8%	Explore
endothelial cell of lymphatic vessel	5 studies	31% ± 8%	Explore
type II pneumocyte	5 studies	20% ± 5%	Explore
goblet cell	5 studies	34% ± 27%	Explore
pericyte	5 studies	25% ± 6%	Explore
smooth muscle cell	5 studies	21% ± 3%	Explore
squamous epithelial cell	4 studies	35% ± 19%	Explore
CD4-positive, alpha-beta T cell	4 studies	25% ± 2%	Explore
granule cell	4 studies	21% ± 6%	Explore
plasma cell	4 studies	33% ± 3%	Explore
cardiac muscle cell	4 studies	21% ± 2%	Explore
lymphocyte	4 studies	36% ± 12%	Explore
retinal rod cell	4 studies	23% ± 5%	Explore
regulatory T cell	4 studies	21% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	21% ± 3%	Explore
conventional dendritic cell	3 studies	28% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	22% ± 3%	Explore
hematopoietic precursor cell	3 studies	35% ± 21%	Explore
non-classical monocyte	3 studies	31% ± 3%	Explore
GABAergic interneuron	3 studies	20% ± 4%	Explore
retinal pigment epithelial cell	3 studies	25% ± 9%	Explore
mononuclear phagocyte	3 studies	33% ± 12%	Explore
leukocyte	3 studies	32% ± 10%	Explore
B cell	3 studies	23% ± 5%	Explore
alveolar macrophage	3 studies	44% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	20% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	19% ± 3%	Explore
transit amplifying cell	3 studies	36% ± 25%	Explore
renal alpha-intercalated cell	3 studies	50% ± 16%	Explore
renal principal cell	3 studies	26% ± 5%	Explore
mucus secreting cell	3 studies	22% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	29% ± 18%	Explore
lung	7 studies	24% ± 6%	Explore
heart	4 studies	19% ± 3%	Explore
liver	4 studies	25% ± 11%	Explore
peripheral blood	3 studies	23% ± 1%	Explore
eye	3 studies	29% ± 10%	Explore
intestine	3 studies	18% ± 0%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6266.68	1445 / 1445	100%	84.81	183 / 183
intestine	100%	6495.46	966 / 966	100%	64.95	527 / 527
lung	100%	5993.13	578 / 578	100%	67.69	1155 / 1155
prostate	100%	4869.13	245 / 245	100%	87.01	502 / 502
stomach	100%	4956.79	359 / 359	100%	63.61	286 / 286
breast	100%	5531.72	459 / 459	100%	68.76	1117 / 1118
ovary	100%	4169.37	180 / 180	100%	36.91	429 / 430
uterus	100%	4775.15	170 / 170	100%	57.09	457 / 459
brain	100%	5194.56	2630 / 2642	100%	69.31	705 / 705
thymus	100%	4390.94	653 / 653	99%	68.67	601 / 605
bladder	100%	5730.81	21 / 21	99%	53.18	499 / 504
kidney	100%	4987.96	89 / 89	98%	53.38	885 / 901
pancreas	98%	2251.72	320 / 328	99%	67.53	177 / 178
adrenal gland	100%	4059.49	258 / 258	97%	39.02	223 / 230
liver	99%	2237.65	223 / 226	97%	30.20	394 / 406
skin	100%	5882.84	1808 / 1809	95%	49.09	449 / 472
adipose	100%	6165.29	1204 / 1204	0%	0	0 / 0
blood vessel	100%	7604.50	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	81.34	29 / 29
muscle	100%	12026.88	803 / 803	0%	0	0 / 0
spleen	100%	5540.84	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	66.25	45 / 45
ureter	0%	0	0 / 0	100%	29.06	1 / 1
peripheral blood	98%	8830.14	907 / 929	0%	0	0 / 0
heart	94%	4594.33	811 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	26.69	72 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0018105	Biological process	peptidyl-serine phosphorylation
GO_0071476	Biological process	cellular hypotonic response
GO_0097066	Biological process	response to thyroid hormone
GO_1901380	Biological process	negative regulation of potassium ion transmembrane transport
GO_0007165	Biological process	signal transduction
GO_0014823	Biological process	response to activity
GO_0035556	Biological process	intracellular signal transduction
GO_1901017	Biological process	negative regulation of potassium ion transmembrane transporter activity
GO_0010800	Biological process	positive regulation of peptidyl-threonine phosphorylation
GO_0071902	Biological process	positive regulation of protein serine/threonine kinase activity
GO_0005576	Cellular component	extracellular region
GO_0030018	Cellular component	Z disc
GO_0070062	Cellular component	extracellular exosome
GO_1902554	Cellular component	serine/threonine protein kinase complex
GO_0034774	Cellular component	secretory granule lumen
GO_1904813	Cellular component	ficolin-1-rich granule lumen
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0019900	Molecular function	kinase binding
GO_0043539	Molecular function	protein serine/threonine kinase activator activity
GO_0030295	Molecular function	protein kinase activator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CAB39
Protein name	Calcium-binding protein 39 (MO25alpha) (Protein Mo25)
Synonyms	CGI-66 MO25
Description	FUNCTION: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1. .
Accessions	ENST00000258418.10 ENST00000409788.7 ENST00000410084.7 Q9Y376

CAB39 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review