BACH1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006281Biological processDNA repair
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0019222Biological processregulation of metabolic process
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0020037Molecular functionheme binding
GO_0005515Molecular functionprotein binding
GO_0098531Molecular functionligand-activated transcription factor activity

IV. Literature review

[source]
Gene nameBACH1
Protein nameTranscription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303)
Transcription factor BACH1t
BTB domain and CNC homolog 1
Synonyms
DescriptionFUNCTION: Transcriptional regulator that acts as a repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK (By similarity). Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway . .

AccessionsENST00000399921.5
C9IYH8
C9JMP6
H7C4B6
ENST00000548219.5
F8VZL7
ENST00000447177.5
ENST00000546469.5
O14867
M0QZP0
ENST00000468059.1
Q9BXM4
ENST00000422809.5
C9IYR0
ENST00000286800.8
ENST00000435072.1
ENST00000547141.5
ENST00000451655.5
ENST00000550131.5
ENST00000548467.1