ARHGAP9 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_0043087Biological processregulation of GTPase activity
GO_0034774Cellular componentsecretory granule lumen
GO_0005737Cellular componentcytoplasm
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0005547Molecular functionphosphatidylinositol-3,4,5-trisphosphate binding
GO_0005515Molecular functionprotein binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameARHGAP9
Protein nameRho GTPase activating protein 9
ARHGAP9
Rho GTPase-activating protein 9 (Rho-type GTPase-activating protein 9)
Synonyms
DescriptionFUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate. .

AccessionsF8VR90
ENST00000393797.7 [Q9BRR9-1]
ENST00000548139.5
ENST00000550130.1
ENST00000550399.5
H0YI33
ENST00000549602.1
F8VQR0
ENST00000552604.5
Q9BRR9
R4GN15
ENST00000552066.1
F8VW89
ENST00000551452.5
ENST00000430041.6 [Q9BRR9-4]
H0YI36
ENST00000393791.8 [Q9BRR9-2]
F8VQY5
F8VSD0
ENST00000552249.1
A0A2X0SF68
ENST00000424809.6 [Q9BRR9-5]
ENST00000550288.6
F8W1N6