ADIPOR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046426Biological processnegative regulation of receptor signaling pathway via JAK-STAT
GO_0019395Biological processfatty acid oxidation
GO_0033211Biological processadiponectin-activated signaling pathway
GO_0019216Biological processregulation of lipid metabolic process
GO_0010906Biological processregulation of glucose metabolic process
GO_1901223Biological processnegative regulation of non-canonical NF-kappaB signal transduction
GO_0010719Biological processnegative regulation of epithelial to mesenchymal transition
GO_0033210Biological processleptin-mediated signaling pathway
GO_0120162Biological processpositive regulation of cold-induced thermogenesis
GO_0009755Biological processhormone-mediated signaling pathway
GO_0046628Biological processpositive regulation of insulin receptor signaling pathway
GO_0010633Biological processnegative regulation of epithelial cell migration
GO_0046427Biological processpositive regulation of receptor signaling pathway via JAK-STAT
GO_0042593Biological processglucose homeostasis
GO_0030308Biological processnegative regulation of cell growth
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0038023Molecular functionsignaling receptor activity
GO_0097003Molecular functionadipokinetic hormone receptor activity
GO_0019901Molecular functionprotein kinase binding
GO_0042802Molecular functionidentical protein binding
GO_0046872Molecular functionmetal ion binding
GO_0055100Molecular functionadiponectin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADIPOR1
Protein nameAdiponectin receptor 1
Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member 1) (Progestin and adipoQ receptor family member I)
SynonymsCGI-45
PAQR1
TESBP1A
DescriptionFUNCTION: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism . Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity). .

AccessionsENST00000367254.7
C9J0W7
ENST00000340990.10
C9JNM5
ENST00000417068.5
ENST00000426229.1
Q96A54
F8W782