Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | LEP-LEPR | LEP_HUMAN - LEPR_HUMAN | Ligand-Receptor |
| Name | leptin-mediated signaling pathway |
| ID | GO_0033210 |
| collection_id | Biological process |
| Exact synonym | leptin-mediated signalling pathway |
| Related synonym | adipocytokine signaling pathway |
| Description | The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. |
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| Genes |