translesion synthesis

I. Literature review

[source]
Nametranslesion synthesis
IDGO_0019985
collection_id

Biological process

Exact synonym

bypass DNA synthesis

Description

The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.

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Genes