Name | Number of supported studies | Average coverage | |
---|---|---|---|
progenitor cell | 6 studies | 32% ± 17% | |
T cell | 6 studies | 42% ± 19% | |
epithelial cell | 6 studies | 29% ± 11% | |
plasmablast | 5 studies | 49% ± 12% | |
B cell | 5 studies | 44% ± 18% | |
transit amplifying cell | 5 studies | 40% ± 15% | |
erythroblast | 5 studies | 52% ± 21% | |
natural killer cell | 5 studies | 36% ± 14% | |
CD8-positive, alpha-beta T cell | 5 studies | 47% ± 21% | |
endothelial cell | 4 studies | 21% ± 3% | |
pro-B cell | 4 studies | 27% ± 3% | |
erythrocyte | 4 studies | 52% ± 28% | |
CD4-positive, alpha-beta T cell | 4 studies | 54% ± 19% | |
fibroblast | 3 studies | 19% ± 2% | |
connective tissue cell | 3 studies | 27% ± 10% | |
macrophage | 3 studies | 25% ± 5% | |
monocyte | 3 studies | 21% ± 1% | |
neural crest cell | 3 studies | 46% ± 12% | |
plasma cell | 3 studies | 30% ± 8% | |
granulocyte monocyte progenitor cell | 3 studies | 53% ± 25% | |
hematopoietic precursor cell | 3 studies | 44% ± 26% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 36% ± 10% | |
germinal center B cell | 3 studies | 34% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 84% | 385.53 | 1526 / 1809 | 87% | 6.46 | 412 / 472 |
stomach | 71% | 105.98 | 255 / 359 | 97% | 10.87 | 278 / 286 |
lung | 75% | 88.59 | 435 / 578 | 89% | 8.25 | 1028 / 1155 |
intestine | 56% | 126.84 | 544 / 966 | 94% | 9.92 | 495 / 527 |
esophagus | 44% | 154.65 | 635 / 1445 | 100% | 16.12 | 183 / 183 |
bladder | 48% | 30.52 | 10 / 21 | 96% | 10.46 | 484 / 504 |
pancreas | 67% | 32.14 | 219 / 328 | 71% | 3.84 | 127 / 178 |
liver | 81% | 62.65 | 182 / 226 | 55% | 3.10 | 224 / 406 |
thymus | 86% | 53.65 | 564 / 653 | 48% | 4.68 | 289 / 605 |
breast | 39% | 23.15 | 180 / 459 | 89% | 6.51 | 1000 / 1118 |
uterus | 16% | 11.12 | 27 / 170 | 99% | 20.23 | 454 / 459 |
ovary | 9% | 11.27 | 16 / 180 | 98% | 10.02 | 421 / 430 |
lymph node | 0% | 0 | 0 / 0 | 100% | 12.88 | 29 / 29 |
tonsil | 0% | 0 | 0 / 0 | 100% | 16.46 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.57 | 1 / 1 |
spleen | 98% | 221.00 | 235 / 241 | 0% | 0 | 0 / 0 |
prostate | 68% | 43.20 | 166 / 245 | 28% | 1.06 | 140 / 502 |
kidney | 57% | 42.24 | 51 / 89 | 26% | 1.00 | 232 / 901 |
adrenal gland | 55% | 38.88 | 143 / 258 | 17% | 1.33 | 40 / 230 |
peripheral blood | 68% | 589.15 | 633 / 929 | 0% | 0 | 0 / 0 |
brain | 25% | 11.80 | 649 / 2642 | 39% | 2.64 | 275 / 705 |
adipose | 29% | 22.04 | 352 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 16% | 9.03 | 218 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 13% | 0.33 | 10 / 80 |
heart | 8% | 5.24 | 73 / 861 | 0% | 0 | 0 / 0 |
muscle | 2% | 0.74 | 16 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006974 | Biological process | DNA damage response |
GO_0009411 | Biological process | response to UV |
GO_0019985 | Biological process | translesion synthesis |
GO_0006260 | Biological process | DNA replication |
GO_0051726 | Biological process | regulation of cell cycle |
GO_0007098 | Biological process | centrosome cycle |
GO_0005813 | Cellular component | centrosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0060090 | Molecular function | molecular adaptor activity |
GO_0003682 | Molecular function | chromatin binding |
Gene name | PCLAF |
Protein name | PCNA-associated factor (Hepatitis C virus NS5A-transactivated protein 9) (HCV NS5A-transactivated protein 9) (Overexpressed in anaplastic thyroid carcinoma 1) (OEATC-1) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF) (PCNA-clamp-associated factor) KIAA0101 PCNA-associated factor (PCNA-associated factor of 15 kDa) (PCNA-clamp-associated factor) |
Synonyms | PAF hCG_2039386 L5 NS5ATP9 KIAA0101 |
Description | FUNCTION: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number. . |
Accessions | Q15004 H0YMA4 ENST00000559519.5 H0YKX3 ENST00000558008.3 G9G6D7 ENST00000300035.9 [Q15004-1] ENST00000380258.6 [Q15004-2] G9G6C4 G9G6H1 |