Molecular function

AP deoxyendoribonuclease activity, abasic deoxyendoribonuclease activity, apurinic deoxyendoribonuclease activity, apurinic/apyrimidinic endodeoxyribonuclease activity, apyrimidinic deoxyendoribonuclease activity, deoxyribonuclease (apurinic or apyrimidinic) activity

Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).

endonuclease VIII activity

Note that this term is does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. Class II AP endonuclease is a nuclease, but not Class I, III and IV.