RNA polymerase I preinitiation complex assembly

I. Literature review

[source]
NameRNA polymerase I preinitiation complex assembly
IDGO_0001188
collection_id

Biological process

Alternative ID

GO:0001189

Exact synonym

RNA polymerase I transcriptional preinitiation complex assembly

Description

The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides.

External URL
Genes