RRN3 | OmnibusX

Name	Number of supported studies	Average coverage
brain	3 studies	20% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	3486.56	459 / 459	100%	68.34	1118 / 1118
esophagus	100%	2312.56	1445 / 1445	100%	39.32	183 / 183
prostate	100%	2436.95	245 / 245	100%	48.43	502 / 502
intestine	100%	2588.08	966 / 966	100%	40.90	526 / 527
ovary	100%	3094.04	180 / 180	100%	27.14	429 / 430
kidney	100%	1662.12	89 / 89	100%	36.89	898 / 901
lung	100%	2183.94	576 / 578	100%	38.96	1155 / 1155
brain	99%	1938.94	2627 / 2642	100%	48.60	705 / 705
bladder	100%	2979.29	21 / 21	99%	38.20	501 / 504
thymus	100%	2446.39	652 / 653	100%	37.54	602 / 605
uterus	100%	2733.35	170 / 170	99%	37.86	456 / 459
stomach	100%	2002.34	359 / 359	99%	37.23	284 / 286
pancreas	100%	1353.27	327 / 328	99%	34.40	177 / 178
adrenal gland	100%	2667.41	258 / 258	99%	48.48	228 / 230
skin	100%	2794.46	1809 / 1809	98%	43.83	464 / 472
liver	100%	2197.62	226 / 226	98%	23.08	397 / 406
adipose	100%	3598.44	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2570.83	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	31.19	29 / 29
muscle	100%	3836.01	803 / 803	0%	0	0 / 0
spleen	100%	2705.22	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	30.32	45 / 45
ureter	0%	0	0 / 0	100%	15.60	1 / 1
heart	98%	1676.72	845 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	94%	26.56	75 / 80
peripheral blood	49%	1105.09	455 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0042254	Biological process	ribosome biogenesis
GO_0001701	Biological process	in utero embryonic development
GO_0006361	Biological process	transcription initiation at RNA polymerase I promoter
GO_0007028	Biological process	cytoplasm organization
GO_0007000	Biological process	nucleolus organization
GO_0048872	Biological process	homeostasis of number of cells
GO_2000142	Biological process	regulation of DNA-templated transcription initiation
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0072332	Biological process	intrinsic apoptotic signaling pathway by p53 class mediator
GO_0048144	Biological process	fibroblast proliferation
GO_1902254	Biological process	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO_0001188	Biological process	RNA polymerase I preinitiation complex assembly
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0001181	Molecular function	RNA polymerase I general transcription initiation factor activity
GO_0001042	Molecular function	RNA polymerase I core binding
GO_0001164	Molecular function	RNA polymerase I core promoter sequence-specific DNA binding
GO_0005515	Molecular function	protein binding

Gene name	RRN3
Protein name	RNA polymerase I-specific transcription initiation factor RRN3 (RRN3 homolog, RNA polymerase I transcription factor) RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA)
Synonyms	TIFIA
Description	FUNCTION: Required for efficient transcription initiation by RNA polymerase I (Pol I). Required for the formation of the competent pre-initiation complex (PIC). .
Accessions	ENST00000634151.1 [Q9NYV6-2] ENST00000616334.2 [Q9NYV6-1] ENST00000327307.11 [Q9NYV6-3] Q9NYV6 ENST00000564131.1 [Q9NYV6-2] F5H148 ENST00000429751.6 ENST00000631800.1 H3BMT1 ENST00000632541.1 [Q9NYV6-3] ENST00000632447.1 ENST00000198767.11 [Q9NYV6-1] ENST00000563559.5

RRN3 report