POLR1E report

I. Expression across cell types

Insufficient scRNA-seq data for expression of POLR1E at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of POLR1E at tissue level.

III. Associated gene sets

GO_0006362Biological processtranscription elongation by RNA polymerase I
GO_0001188Biological processRNA polymerase I preinitiation complex assembly
GO_0042790Biological processnucleolar large rRNA transcription by RNA polymerase I
GO_0006361Biological processtranscription initiation at RNA polymerase I promoter
GO_0005736Cellular componentRNA polymerase I complex
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0001650Cellular componentfibrillar center
GO_0003677Molecular functionDNA binding
GO_0001179Molecular functionRNA polymerase I general transcription initiation factor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePOLR1E
Protein nameDNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)
RNA polymerase I subunit E
SynonymsPAF53
PRAF1
DescriptionFUNCTION: Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates . Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF . .

AccessionsE7EX70
Q9GZS1
ENST00000377798.9 [Q9GZS1-2]
ENST00000442009.6
ENST00000377792.3 [Q9GZS1-1]