Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 3 studies | 24% ± 5% | |
| astrocyte | 3 studies | 18% ± 3% |
Insufficient scRNA-seq data for expression of TAF1C at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 4858.13 | 258 / 258 | 100% | 21.03 | 230 / 230 |
| esophagus | 100% | 4536.60 | 1445 / 1445 | 100% | 25.71 | 183 / 183 |
| skin | 100% | 4572.50 | 1809 / 1809 | 100% | 26.94 | 471 / 472 |
| uterus | 100% | 7925.40 | 170 / 170 | 100% | 26.12 | 458 / 459 |
| intestine | 100% | 5319.86 | 966 / 966 | 100% | 19.46 | 525 / 527 |
| prostate | 100% | 7799.62 | 245 / 245 | 100% | 18.42 | 500 / 502 |
| thymus | 100% | 7941.30 | 653 / 653 | 100% | 21.37 | 602 / 605 |
| pancreas | 100% | 3420.36 | 328 / 328 | 99% | 21.88 | 177 / 178 |
| bladder | 100% | 5610.43 | 21 / 21 | 99% | 25.10 | 501 / 504 |
| lung | 100% | 6014.76 | 578 / 578 | 99% | 21.31 | 1143 / 1155 |
| ovary | 100% | 9509.26 | 180 / 180 | 99% | 18.77 | 425 / 430 |
| stomach | 100% | 4428.60 | 359 / 359 | 99% | 18.62 | 282 / 286 |
| breast | 100% | 6898.65 | 459 / 459 | 99% | 17.13 | 1102 / 1118 |
| kidney | 100% | 5431.13 | 89 / 89 | 98% | 21.83 | 886 / 901 |
| brain | 97% | 3340.68 | 2566 / 2642 | 100% | 40.05 | 705 / 705 |
| liver | 100% | 2584.35 | 226 / 226 | 93% | 11.08 | 378 / 406 |
| adipose | 100% | 6008.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 23.08 | 29 / 29 |
| spleen | 100% | 11838.41 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 19.15 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 25.92 | 1 / 1 |
| blood vessel | 100% | 3826.26 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 100% | 3191.37 | 857 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 19.69 | 79 / 80 |
| muscle | 97% | 2027.32 | 782 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 85% | 2007.40 | 791 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_0001188 | Biological process | RNA polymerase I preinitiation complex assembly |
| GO_0006361 | Biological process | transcription initiation at RNA polymerase I promoter |
| GO_0006360 | Biological process | transcription by RNA polymerase I |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005668 | Cellular component | RNA polymerase transcription factor SL1 complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0001181 | Molecular function | RNA polymerase I general transcription initiation factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0001164 | Molecular function | RNA polymerase I core promoter sequence-specific DNA binding |
| Gene name | TAF1C |
| Protein name | TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) TATA-box binding protein associated factor, RNA polymerase I subunit C |
| Synonyms | |
| Description | FUNCTION: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. . |
| Accessions | ENST00000566732.6 [Q15572-6] ENST00000341690.10 [Q15572-2] ENST00000566903.5 H3BUZ7 Q15572 H3BNH3 H3BTQ6 H3BMQ4 H3BR71 ENST00000567759.5 [Q15572-1] H3BQZ8 ENST00000563428.5 H3BQH8 ENST00000570117.5 [Q15572-4] ENST00000541676.5 [Q15572-4] ENST00000569609.5 ENST00000564345.5 ENST00000569505.5 H3BR91 ENST00000564454.1 ENST00000568265.1 ENST00000561955.1 |