TAF1C report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TAF1C at tissue level.

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0001188Biological processRNA polymerase I preinitiation complex assembly
GO_0006361Biological processtranscription initiation at RNA polymerase I promoter
GO_0006360Biological processtranscription by RNA polymerase I
GO_0005730Cellular componentnucleolus
GO_0005668Cellular componentRNA polymerase transcription factor SL1 complex
GO_0005654Cellular componentnucleoplasm
GO_0001650Cellular componentfibrillar center
GO_0001181Molecular functionRNA polymerase I general transcription initiation factor activity
GO_0005515Molecular functionprotein binding
GO_0001164Molecular functionRNA polymerase I core promoter sequence-specific DNA binding

IV. Literature review

[source]
Gene nameTAF1C
Protein nameTATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C)
TATA-box binding protein associated factor, RNA polymerase I subunit C
Synonyms
DescriptionFUNCTION: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. .

AccessionsENST00000566732.6 [Q15572-6]
ENST00000341690.10 [Q15572-2]
ENST00000566903.5
H3BUZ7
Q15572
H3BNH3
H3BTQ6
H3BMQ4
H3BR71
ENST00000567759.5 [Q15572-1]
H3BQZ8
ENST00000563428.5
H3BQH8
ENST00000570117.5 [Q15572-4]
ENST00000541676.5 [Q15572-4]
ENST00000569609.5
ENST00000564345.5
ENST00000569505.5
H3BR91
ENST00000564454.1
ENST00000568265.1
ENST00000561955.1