TAF1B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006351Biological processDNA-templated transcription
GO_0001188Biological processRNA polymerase I preinitiation complex assembly
GO_0042790Biological processnucleolar large rRNA transcription by RNA polymerase I
GO_0070860Cellular componentRNA polymerase I core factor complex
GO_0005730Cellular componentnucleolus
GO_0005668Cellular componentRNA polymerase transcription factor SL1 complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0017025Molecular functionTBP-class protein binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0001164Molecular functionRNA polymerase I core promoter sequence-specific DNA binding

IV. Literature review

[source]
Gene nameTAF1B
Protein nameTATA box-binding protein-associated factor RNA polymerase I subunit B (TATA box-binding protein-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B)
TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 63 kDa) (TAFI63) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B)
TATA-box binding protein associated factor, RNA polymerase I subunit B
Synonyms
DescriptionFUNCTION: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3. .

FUNCTION: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3. .

AccessionsU3KQ75
ENST00000263663.10 [Q53T94-1]
F8WE32
F8WDU0
ENST00000625239.2
ENST00000492648.2
ENST00000434858.5
Q53T94
ENST00000416181.1