VOPP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	34 studies	27% ± 8%	Explore
macrophage	25 studies	30% ± 13%	Explore
endothelial cell	24 studies	29% ± 10%	Explore
memory B cell	19 studies	27% ± 5%	Explore
conventional dendritic cell	18 studies	24% ± 7%	Explore
plasma cell	17 studies	46% ± 16%	Explore
dendritic cell	15 studies	44% ± 15%	Explore
regulatory T cell	14 studies	21% ± 4%	Explore
myeloid cell	12 studies	26% ± 6%	Explore
microglial cell	11 studies	41% ± 15%	Explore
natural killer cell	11 studies	22% ± 5%	Explore
plasmablast	10 studies	53% ± 23%	Explore
monocyte	9 studies	27% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	20% ± 3%	Explore
CD4-positive, alpha-beta T cell	9 studies	20% ± 5%	Explore
retinal rod cell	9 studies	47% ± 20%	Explore
CD8-positive, alpha-beta T cell	9 studies	21% ± 4%	Explore
T cell	9 studies	21% ± 4%	Explore
astrocyte	9 studies	33% ± 12%	Explore
plasmacytoid dendritic cell	9 studies	25% ± 8%	Explore
GABAergic neuron	8 studies	41% ± 20%	Explore
glutamatergic neuron	8 studies	43% ± 24%	Explore
retinal cone cell	8 studies	66% ± 21%	Explore
epithelial cell	8 studies	26% ± 8%	Explore
naive B cell	7 studies	20% ± 6%	Explore
IgG plasma cell	7 studies	27% ± 11%	Explore
ciliated cell	7 studies	21% ± 4%	Explore
T follicular helper cell	7 studies	23% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 5%	Explore
mononuclear phagocyte	6 studies	28% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	22% ± 4%	Explore
mature NK T cell	5 studies	20% ± 6%	Explore
IgA plasma cell	5 studies	33% ± 14%	Explore
neuron	5 studies	42% ± 17%	Explore
Mueller cell	5 studies	31% ± 13%	Explore
abnormal cell	5 studies	36% ± 15%	Explore
goblet cell	5 studies	25% ± 11%	Explore
interneuron	5 studies	44% ± 22%	Explore
gamma-delta T cell	5 studies	18% ± 2%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	18% ± 2%	Explore
oligodendrocyte precursor cell	4 studies	21% ± 4%	Explore
precursor B cell	4 studies	23% ± 6%	Explore
fibroblast	4 studies	17% ± 1%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	19% ± 4%	Explore
lymphocyte	4 studies	30% ± 11%	Explore
endothelial cell of lymphatic vessel	4 studies	23% ± 5%	Explore
basal cell	4 studies	24% ± 5%	Explore
pancreatic A cell	3 studies	40% ± 14%	Explore
type B pancreatic cell	3 studies	50% ± 17%	Explore
classical monocyte	3 studies	25% ± 6%	Explore
non-classical monocyte	3 studies	28% ± 10%	Explore
capillary endothelial cell	3 studies	18% ± 2%	Explore
endothelial cell of artery	3 studies	18% ± 2%	Explore
GABAergic interneuron	3 studies	29% ± 2%	Explore
retinal ganglion cell	3 studies	31% ± 5%	Explore
retina horizontal cell	3 studies	28% ± 8%	Explore
germinal center B cell	3 studies	25% ± 2%	Explore
endothelial cell of vascular tree	3 studies	28% ± 10%	Explore
IgM plasma cell	3 studies	36% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	23% ± 6%	Explore
ependymal cell	3 studies	32% ± 10%	Explore
enteroendocrine cell	3 studies	27% ± 6%	Explore
leukocyte	3 studies	30% ± 7%	Explore
alveolar macrophage	3 studies	34% ± 6%	Explore
transit amplifying cell	3 studies	23% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	18% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	13 studies	30% ± 15%	Explore
eye	8 studies	37% ± 15%	Explore
peripheral blood	6 studies	20% ± 5%	Explore
lung	5 studies	22% ± 4%	Explore
pancreas	3 studies	42% ± 12%	Explore
kidney	3 studies	17% ± 1%	Explore
intestine	3 studies	19% ± 2%	Explore
adipose	3 studies	18% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	1797.50	180 / 180	100%	29.74	430 / 430
stomach	100%	1446.56	359 / 359	100%	35.59	286 / 286
brain	100%	2449.02	2641 / 2642	100%	94.05	705 / 705
lung	100%	2055.59	578 / 578	100%	41.64	1153 / 1155
uterus	100%	2293.32	170 / 170	100%	35.43	458 / 459
thymus	100%	1757.44	652 / 653	100%	26.19	604 / 605
intestine	100%	2261.78	966 / 966	100%	36.39	525 / 527
kidney	100%	2283.90	89 / 89	100%	32.55	897 / 901
breast	100%	1887.83	459 / 459	99%	39.20	1112 / 1118
bladder	100%	1677.29	21 / 21	99%	33.55	501 / 504
esophagus	100%	1114.95	1441 / 1445	99%	40.52	182 / 183
prostate	100%	1932.39	245 / 245	98%	17.80	494 / 502
pancreas	97%	937.06	318 / 328	99%	39.85	177 / 178
adrenal gland	100%	1212.09	258 / 258	91%	15.70	209 / 230
liver	95%	930.04	215 / 226	93%	15.93	378 / 406
skin	99%	1778.82	1793 / 1809	76%	17.19	360 / 472
adipose	100%	2292.21	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	165.72	29 / 29
spleen	100%	5705.57	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	42.73	45 / 45
ureter	0%	0	0 / 0	100%	22.66	1 / 1
blood vessel	100%	2626.50	1330 / 1335	0%	0	0 / 0
muscle	99%	1250.83	795 / 803	0%	0	0 / 0
peripheral blood	98%	4333.99	912 / 929	0%	0	0 / 0
heart	98%	937.17	845 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	83%	12.28	66 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0005764	Cellular component	lysosome
GO_0031090	Cellular component	organelle membrane
GO_0005768	Cellular component	endosome
GO_0031902	Cellular component	late endosome membrane
GO_0030659	Cellular component	cytoplasmic vesicle membrane
GO_0005765	Cellular component	lysosomal membrane
GO_0005770	Cellular component	late endosome
GO_0019899	Molecular function	enzyme binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	VOPP1
Protein name	WW domain binding protein VOPP1 (EGFR-coamplified and overexpressed protein) (Vesicular, overexpressed in cancer, prosurvival protein 1) WW domain binding protein VOPP1 (EGFR-coamplified and overexpressed protein) (ECop) (Glioblastoma-amplified secreted protein) (Putative NF-kappa-B-activating protein 055N) (Vesicular, overexpressed in cancer, prosurvival protein 1) VOPP1 WW domain binding protein
Synonyms	ECOP GASP
Description	FUNCTION: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed . May sequester WWOX in lysosomal vesicles and thereby regulate WWOX role as tumor suppressor . .
Accessions	ENST00000625836.2 [Q96AW1-3] ENST00000428648.5 ENST00000454227.5 C9JVH1 C9JQ18 C9J827 ENST00000417399.5 ENST00000418904.5 [Q96AW1-4] ENST00000427700.1 C9JF99 ENST00000453256.5 ENST00000452832.5 C9JTY8 C9JIM1 ENST00000414113.5 ENST00000428097.5 ENST00000285279.10 [Q96AW1-1] ENST00000433959.5 [Q96AW1-2] ENST00000455023.5 C9J548 Q96AW1

VOPP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review