UHMK1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	24 studies	23% ± 7%	Explore
B cell	13 studies	22% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	30% ± 8%	Explore
CD8-positive, alpha-beta T cell	13 studies	22% ± 6%	Explore
naive B cell	12 studies	21% ± 5%	Explore
memory B cell	12 studies	22% ± 7%	Explore
non-classical monocyte	11 studies	25% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	21% ± 5%	Explore
mature NK T cell	11 studies	23% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	22% ± 6%	Explore
regulatory T cell	11 studies	20% ± 3%	Explore
gamma-delta T cell	11 studies	25% ± 7%	Explore
endothelial cell	9 studies	22% ± 5%	Explore
mucosal invariant T cell	9 studies	23% ± 5%	Explore
plasmacytoid dendritic cell	9 studies	21% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	25% ± 9%	Explore
ciliated cell	8 studies	25% ± 7%	Explore
epithelial cell	8 studies	29% ± 12%	Explore
CD4-positive, alpha-beta T cell	8 studies	20% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	22% ± 5%	Explore
T cell	6 studies	23% ± 6%	Explore
basal cell	6 studies	26% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	28% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	21% ± 4%	Explore
macrophage	6 studies	20% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
classical monocyte	5 studies	24% ± 8%	Explore
renal alpha-intercalated cell	5 studies	38% ± 11%	Explore
exhausted T cell	4 studies	24% ± 7%	Explore
neuron	4 studies	25% ± 4%	Explore
monocyte	4 studies	20% ± 3%	Explore
GABAergic neuron	4 studies	39% ± 9%	Explore
glutamatergic neuron	4 studies	48% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	23% ± 6%	Explore
ionocyte	3 studies	25% ± 3%	Explore
secretory cell	3 studies	27% ± 5%	Explore
conventional dendritic cell	3 studies	32% ± 12%	Explore
lymphocyte	3 studies	20% ± 6%	Explore
abnormal cell	3 studies	31% ± 7%	Explore
dendritic cell	3 studies	35% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	21% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	23% ± 5%	Explore
innate lymphoid cell	3 studies	19% ± 2%	Explore
double negative thymocyte	3 studies	31% ± 4%	Explore
astrocyte	3 studies	23% ± 4%	Explore
oligodendrocyte	3 studies	22% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	22% ± 5%	Explore
brain	4 studies	37% ± 8%	Explore
lung	3 studies	29% ± 3%	Explore
kidney	3 studies	18% ± 1%	Explore
liver	3 studies	26% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3919.20	1445 / 1445	100%	64.53	183 / 183
lung	100%	5914.54	578 / 578	100%	60.86	1155 / 1155
breast	100%	5336.13	459 / 459	100%	94.07	1116 / 1118
uterus	100%	3719.53	170 / 170	100%	49.67	458 / 459
liver	100%	4580.19	226 / 226	100%	39.65	404 / 406
thymus	100%	4291.10	653 / 653	100%	38.92	602 / 605
brain	100%	5242.54	2640 / 2642	100%	30.23	702 / 705
prostate	100%	4252.38	245 / 245	99%	40.84	498 / 502
ovary	100%	3456.32	180 / 180	99%	26.74	426 / 430
kidney	100%	5225.97	89 / 89	99%	44.90	888 / 901
bladder	100%	3917.43	21 / 21	98%	48.40	496 / 504
pancreas	99%	2099.60	325 / 328	99%	40.64	176 / 178
stomach	100%	3249.44	359 / 359	97%	42.69	278 / 286
intestine	100%	4380.46	966 / 966	97%	37.41	510 / 527
adrenal gland	100%	6699.38	258 / 258	97%	45.01	222 / 230
skin	100%	5267.99	1807 / 1809	96%	54.50	451 / 472
lymph node	0%	0	0 / 0	100%	44.46	29 / 29
muscle	100%	6266.13	803 / 803	0%	0	0 / 0
spleen	100%	5443.77	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	53.29	45 / 45
ureter	0%	0	0 / 0	100%	16.92	1 / 1
adipose	100%	5936.01	1203 / 1204	0%	0	0 / 0
blood vessel	99%	3105.61	1328 / 1335	0%	0	0 / 0
heart	97%	2471.60	831 / 861	0%	0	0 / 0
peripheral blood	90%	4818.86	840 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	71%	16.84	57 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0018105	Biological process	peptidyl-serine phosphorylation
GO_0045948	Biological process	positive regulation of translational initiation
GO_0031175	Biological process	neuron projection development
GO_0046777	Biological process	protein autophosphorylation
GO_0046825	Biological process	regulation of protein export from nucleus
GO_0051726	Biological process	regulation of cell cycle
GO_0016607	Cellular component	nuclear speck
GO_0005654	Cellular component	nucleoplasm
GO_0071598	Cellular component	neuronal ribonucleoprotein granule
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0030424	Cellular component	axon
GO_0032839	Cellular component	dendrite cytoplasm
GO_0005634	Cellular component	nucleus
GO_0019899	Molecular function	enzyme binding
GO_0106310	Molecular function	protein serine kinase activity
GO_0016740	Molecular function	transferase activity
GO_0043021	Molecular function	ribonucleoprotein complex binding
GO_0004674	Molecular function	protein serine/threonine kinase activity
GO_1990935	Molecular function	splicing factor binding
GO_0005524	Molecular function	ATP binding
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	UHMK1
Protein name	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1)
Synonyms	KIST KIS
Description	FUNCTION: Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity). .
Accessions	ENST00000489294.2 [Q8TAS1-1] Q8TAS1 ENST00000545294.5 [Q8TAS1-3] ENST00000538489.5 [Q8TAS1-2]

UHMK1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review