TSPYL1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	14 studies	23% ± 7%	Explore
B cell	13 studies	22% ± 7%	Explore
smooth muscle cell	12 studies	21% ± 6%	Explore
fibroblast	12 studies	25% ± 9%	Explore
T cell	11 studies	22% ± 4%	Explore
regulatory T cell	11 studies	20% ± 6%	Explore
ciliated cell	10 studies	29% ± 12%	Explore
memory B cell	10 studies	22% ± 5%	Explore
naive B cell	10 studies	22% ± 5%	Explore
mast cell	9 studies	24% ± 7%	Explore
glutamatergic neuron	9 studies	50% ± 18%	Explore
pericyte	9 studies	22% ± 4%	Explore
basal cell	8 studies	28% ± 15%	Explore
connective tissue cell	7 studies	25% ± 7%	Explore
CD8-positive, alpha-beta T cell	7 studies	22% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	23% ± 5%	Explore
endothelial cell	6 studies	30% ± 12%	Explore
gamma-delta T cell	6 studies	25% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	21% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	23% ± 7%	Explore
kidney loop of Henle epithelial cell	5 studies	21% ± 4%	Explore
myofibroblast cell	5 studies	25% ± 8%	Explore
macrophage	5 studies	18% ± 4%	Explore
neuron	5 studies	42% ± 19%	Explore
GABAergic neuron	5 studies	44% ± 15%	Explore
mucosal invariant T cell	5 studies	26% ± 2%	Explore
epithelial cell	5 studies	43% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	25% ± 5%	Explore
type B pancreatic cell	4 studies	39% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	18% ± 1%	Explore
retinal ganglion cell	4 studies	46% ± 23%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	24% ± 6%	Explore
natural killer cell	4 studies	18% ± 1%	Explore
goblet cell	4 studies	24% ± 10%	Explore
T follicular helper cell	4 studies	30% ± 11%	Explore
interneuron	4 studies	45% ± 21%	Explore
epithelial cell of proximal tubule	3 studies	22% ± 5%	Explore
retinal bipolar neuron	3 studies	34% ± 11%	Explore
amacrine cell	3 studies	39% ± 13%	Explore
Mueller cell	3 studies	23% ± 11%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	23% ± 7%	Explore
innate lymphoid cell	3 studies	25% ± 9%	Explore
granulocyte	3 studies	20% ± 5%	Explore
type I pneumocyte	3 studies	28% ± 9%	Explore
dendritic cell	3 studies	28% ± 11%	Explore
pancreatic ductal cell	3 studies	37% ± 14%	Explore
intestinal crypt stem cell	3 studies	23% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	21% ± 3%	Explore
T-helper 17 cell	3 studies	26% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	27% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	11 studies	31% ± 16%	Explore
peripheral blood	7 studies	22% ± 4%	Explore
lung	7 studies	26% ± 11%	Explore
eye	6 studies	22% ± 9%	Explore
intestine	5 studies	22% ± 10%	Explore
pancreas	3 studies	39% ± 12%	Explore
uterus	3 studies	24% ± 8%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	5454.78	180 / 180	100%	26.41	429 / 430
breast	100%	4044.96	459 / 459	100%	46.76	1115 / 1118
intestine	100%	4842.31	966 / 966	100%	23.45	525 / 527
prostate	100%	5340.16	244 / 245	100%	58.65	502 / 502
thymus	100%	5024.50	652 / 653	100%	61.60	603 / 605
esophagus	100%	4955.65	1443 / 1445	99%	20.97	182 / 183
brain	99%	12935.69	2623 / 2642	100%	43.85	705 / 705
stomach	100%	4514.22	359 / 359	99%	21.99	283 / 286
adrenal gland	100%	11655.88	258 / 258	99%	55.90	227 / 230
uterus	99%	4020.24	169 / 170	99%	26.12	455 / 459
lung	99%	3628.31	573 / 578	99%	25.24	1148 / 1155
bladder	100%	5039.29	21 / 21	98%	24.31	496 / 504
kidney	100%	5398.44	89 / 89	98%	38.93	886 / 901
pancreas	98%	2956.71	321 / 328	99%	24.85	177 / 178
liver	100%	3406.03	225 / 226	94%	15.89	382 / 406
skin	100%	4435.52	1807 / 1809	91%	17.53	430 / 472
blood vessel	100%	4888.92	1335 / 1335	0%	0	0 / 0
spleen	100%	4745.71	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	26.55	45 / 45
muscle	100%	8350.85	802 / 803	0%	0	0 / 0
adipose	100%	3750.92	1202 / 1204	0%	0	0 / 0
heart	93%	3887.43	798 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	18.11	26 / 29
eye	0%	0	0 / 0	78%	13.11	62 / 80
peripheral blood	57%	1479.68	529 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1