TRIP11 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0003413Biological processchondrocyte differentiation involved in endochondral bone morphogenesis
GO_0099041Biological processvesicle tethering to Golgi
GO_0060122Biological processinner ear receptor cell stereocilium organization
GO_0003281Biological processventricular septum development
GO_0007030Biological processGolgi organization
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0051216Biological processcartilage development
GO_0090161Biological processGolgi ribbon formation
GO_0006486Biological processprotein glycosylation
GO_0071806Biological processprotein transmembrane transport
GO_0005801Cellular componentcis-Golgi network
GO_0005856Cellular componentcytoskeleton
GO_0002081Cellular componentouter acrosomal membrane
GO_0005794Cellular componentGolgi apparatus
GO_0033116Cellular componentendoplasmic reticulum-Golgi intermediate compartment membrane
GO_0000139Cellular componentGolgi membrane
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0030133Cellular componenttransport vesicle
GO_0002079Cellular componentinner acrosomal membrane
GO_0031267Molecular functionsmall GTPase binding
GO_0003713Molecular functiontranscription coactivator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTRIP11
Protein nameThyroid hormone receptor interactor 11
Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230)
SynonymsCEV14
DescriptionFUNCTION: Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function . It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex . Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. .

AccessionsQ15643
ENST00000267622.8 [Q15643-1]
G3V4R7
ENST00000555516.6
H0YJ97
H0YJI2
ENST00000554357.5
ENST00000557017.1