TENT2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	22 studies	32% ± 14%	Explore
astrocyte	17 studies	37% ± 18%	Explore
macrophage	14 studies	43% ± 23%	Explore
B cell	12 studies	25% ± 8%	Explore
oligodendrocyte	12 studies	42% ± 15%	Explore
microglial cell	12 studies	48% ± 15%	Explore
natural killer cell	11 studies	24% ± 9%	Explore
glutamatergic neuron	10 studies	46% ± 26%	Explore
oligodendrocyte precursor cell	10 studies	42% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	22% ± 7%	Explore
GABAergic neuron	9 studies	43% ± 19%	Explore
adipocyte	9 studies	44% ± 13%	Explore
fibroblast	9 studies	37% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	21% ± 6%	Explore
myeloid cell	8 studies	41% ± 15%	Explore
epithelial cell	8 studies	37% ± 18%	Explore
dendritic cell	8 studies	36% ± 10%	Explore
mast cell	8 studies	26% ± 10%	Explore
smooth muscle cell	8 studies	29% ± 9%	Explore
CD4-positive, alpha-beta T cell	7 studies	21% ± 3%	Explore
pericyte	7 studies	31% ± 12%	Explore
CD8-positive, alpha-beta T cell	7 studies	20% ± 3%	Explore
T cell	7 studies	25% ± 8%	Explore
mucosal invariant T cell	6 studies	20% ± 3%	Explore
monocyte	6 studies	42% ± 11%	Explore
endothelial cell of lymphatic vessel	6 studies	36% ± 13%	Explore
naive B cell	5 studies	20% ± 3%	Explore
cardiac muscle cell	5 studies	40% ± 11%	Explore
ciliated cell	5 studies	27% ± 9%	Explore
interneuron	5 studies	48% ± 20%	Explore
classical monocyte	4 studies	24% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	23% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	21% ± 4%	Explore
non-classical monocyte	4 studies	28% ± 8%	Explore
neuron	4 studies	49% ± 16%	Explore
plasma cell	4 studies	29% ± 3%	Explore
lymphocyte	4 studies	33% ± 15%	Explore
amacrine cell	4 studies	29% ± 10%	Explore
retina horizontal cell	4 studies	35% ± 14%	Explore
retinal rod cell	4 studies	24% ± 6%	Explore
type I pneumocyte	4 studies	34% ± 12%	Explore
type II pneumocyte	4 studies	32% ± 10%	Explore
gamma-delta T cell	4 studies	21% ± 7%	Explore
basal cell	4 studies	41% ± 22%	Explore
plasmacytoid dendritic cell	4 studies	20% ± 4%	Explore
conventional dendritic cell	3 studies	24% ± 8%	Explore
mesothelial cell	3 studies	33% ± 12%	Explore
mononuclear phagocyte	3 studies	39% ± 8%	Explore
vein endothelial cell	3 studies	34% ± 19%	Explore
Mueller cell	3 studies	36% ± 9%	Explore
glycinergic amacrine cell	3 studies	26% ± 7%	Explore
retinal ganglion cell	3 studies	23% ± 10%	Explore
endothelial cell of vascular tree	3 studies	34% ± 17%	Explore
abnormal cell	3 studies	30% ± 19%	Explore
ependymal cell	3 studies	37% ± 15%	Explore
alveolar macrophage	3 studies	51% ± 11%	Explore
capillary endothelial cell	3 studies	25% ± 5%	Explore
club cell	3 studies	37% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	17% ± 1%	Explore
goblet cell	3 studies	39% ± 29%	Explore
leukocyte	3 studies	50% ± 7%	Explore
transit amplifying cell	3 studies	39% ± 32%	Explore
granule cell	3 studies	28% ± 6%	Explore
mural cell	3 studies	38% ± 13%	Explore
regulatory T cell	3 studies	20% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	14 studies	42% ± 22%	Explore
lung	6 studies	28% ± 11%	Explore
peripheral blood	5 studies	20% ± 4%	Explore
heart	4 studies	35% ± 5%	Explore
eye	4 studies	39% ± 19%	Explore
intestine	3 studies	18% ± 2%	Explore
adipose	3 studies	41% ± 11%	Explore
kidney	3 studies	24% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2411.46	1445 / 1445	100%	24.91	183 / 183
lung	100%	2991.11	578 / 578	100%	25.38	1155 / 1155
ovary	100%	3359.18	180 / 180	100%	17.22	430 / 430
breast	100%	3421.34	459 / 459	100%	34.47	1117 / 1118
bladder	100%	2854.29	21 / 21	100%	23.56	503 / 504
kidney	100%	2157.70	89 / 89	100%	27.33	899 / 901
thymus	100%	3247.42	653 / 653	100%	35.10	603 / 605
intestine	100%	2817.53	966 / 966	100%	24.44	525 / 527
prostate	100%	2647.73	245 / 245	100%	20.27	500 / 502
adrenal gland	100%	2501.32	258 / 258	100%	17.59	229 / 230
uterus	100%	3144.58	170 / 170	100%	24.15	457 / 459
brain	99%	1574.15	2621 / 2642	100%	24.78	705 / 705
pancreas	100%	1458.72	327 / 328	99%	23.24	177 / 178
liver	100%	1522.65	226 / 226	99%	15.33	402 / 406
stomach	100%	2125.56	359 / 359	99%	24.58	283 / 286
skin	100%	3228.74	1809 / 1809	95%	24.94	449 / 472
blood vessel	100%	2710.97	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	30.90	29 / 29
spleen	100%	4296.32	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	26.37	45 / 45
ureter	0%	0	0 / 0	100%	5.20	1 / 1
adipose	100%	3186.71	1203 / 1204	0%	0	0 / 0
muscle	100%	1681.15	802 / 803	0%	0	0 / 0
heart	98%	1386.09	848 / 861	0%	0	0 / 0
peripheral blood	96%	2641.34	896 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	84%	12.38	67 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0002244	Biological process	hematopoietic progenitor cell differentiation
GO_0071044	Biological process	histone mRNA catabolic process
GO_2000626	Biological process	negative regulation of miRNA catabolic process
GO_0031124	Biological process	mRNA 3'-end processing
GO_0031380	Cellular component	nuclear RNA-directed RNA polymerase complex
GO_0005737	Cellular component	cytoplasm
GO_1990817	Molecular function	poly(A) RNA polymerase activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding

IV. Literature review

[source]

Gene name	TENT2
Protein name	polynucleotide adenylyltransferase (EC 2.7.7.19) Poly(A) RNA polymerase GLD2 (hGLD-2) (EC 2.7.7.19) (PAP-associated domain-containing protein 4) (Terminal nucleotidyltransferase 2) (Terminal uridylyltransferase 2) (TUTase 2)
Synonyms	GLD2 PAPD4
Description	FUNCTION: Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail . In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs . Does not play a role in replication-dependent histone mRNA degradation . Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs . .
Accessions	ENST00000504233.5 ENST00000423041.6 [Q6PIY7-2] D6RAF2 ENST00000453514.6 [Q6PIY7-1] ENST00000296783.7 [Q6PIY7-1] Q6PIY7

TENT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review