TC2N report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	27 studies	29% ± 11%	Explore
T cell	24 studies	29% ± 11%	Explore
CD8-positive, alpha-beta T cell	24 studies	28% ± 9%	Explore
endothelial cell of lymphatic vessel	16 studies	35% ± 15%	Explore
mucosal invariant T cell	16 studies	43% ± 16%	Explore
mature NK T cell	15 studies	26% ± 9%	Explore
ciliated cell	14 studies	31% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	33% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	29% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	30% ± 8%	Explore
natural killer cell	12 studies	21% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	32% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	28% ± 6%	Explore
gamma-delta T cell	11 studies	29% ± 9%	Explore
epithelial cell	10 studies	29% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	36% ± 15%	Explore
type II pneumocyte	7 studies	30% ± 9%	Explore
club cell	7 studies	27% ± 10%	Explore
respiratory goblet cell	7 studies	35% ± 13%	Explore
secretory cell	6 studies	22% ± 6%	Explore
regulatory T cell	6 studies	19% ± 3%	Explore
T follicular helper cell	6 studies	31% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	26% ± 7%	Explore
exhausted T cell	5 studies	31% ± 6%	Explore
fibroblast	5 studies	20% ± 4%	Explore
lymphocyte	5 studies	45% ± 18%	Explore
goblet cell	5 studies	37% ± 28%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	31% ± 12%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	31% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	28% ± 7%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	21% ± 4%	Explore
type I pneumocyte	4 studies	23% ± 6%	Explore
squamous epithelial cell	3 studies	38% ± 23%	Explore
leukocyte	3 studies	33% ± 24%	Explore
serous secreting cell	3 studies	19% ± 2%	Explore
innate lymphoid cell	3 studies	25% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	16% ± 1%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	26% ± 7%	Explore
mucus secreting cell	3 studies	26% ± 5%	Explore
basal cell	3 studies	28% ± 5%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	18% ± 2%	Explore
lung	5 studies	22% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	99%	3580.29	243 / 245	99%	61.29	499 / 502
breast	100%	4905.03	459 / 459	98%	88.06	1092 / 1118
pancreas	100%	11588.51	328 / 328	95%	40.81	169 / 178
lung	99%	2948.07	574 / 578	95%	45.93	1099 / 1155
stomach	99%	3076.84	357 / 359	94%	39.97	268 / 286
intestine	97%	2178.64	939 / 966	94%	37.45	495 / 527
esophagus	93%	1929.92	1350 / 1445	95%	48.90	173 / 183
uterus	99%	2586.72	168 / 170	79%	28.86	364 / 459
ovary	83%	1179.67	149 / 180	94%	27.42	405 / 430
bladder	81%	1679.33	17 / 21	89%	31.28	449 / 504
thymus	100%	2703.68	651 / 653	64%	9.96	386 / 605
kidney	82%	884.78	73 / 89	63%	10.03	565 / 901
spleen	100%	1622.00	241 / 241	0%	0	0 / 0
blood vessel	99%	5656.93	1328 / 1335	0%	0	0 / 0
adipose	98%	2272.70	1184 / 1204	0%	0	0 / 0
skin	72%	1801.24	1302 / 1809	18%	3.10	86 / 472
tonsil	0%	0	0 / 0	82%	22.74	37 / 45
peripheral blood	58%	1039.17	538 / 929	0%	0	0 / 0
heart	57%	719.48	493 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	45%	8.03	13 / 29
liver	12%	93.93	27 / 226	24%	5.60	98 / 406
adrenal gland	33%	261.83	85 / 258	1%	0.34	3 / 230
muscle	19%	141.73	152 / 803	0%	0	0 / 0
brain	3%	21.20	78 / 2642	9%	1.23	64 / 705
eye	0%	0	0 / 0	10%	1.32	8 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1