Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 2300.84 | 578 / 578 | 92% | 9.31 | 1060 / 1155 |
breast | 85% | 368.20 | 388 / 459 | 89% | 6.43 | 993 / 1118 |
stomach | 79% | 344.67 | 283 / 359 | 74% | 6.37 | 211 / 286 |
intestine | 81% | 591.51 | 785 / 966 | 67% | 4.49 | 351 / 527 |
bladder | 81% | 404.24 | 17 / 21 | 62% | 4.85 | 312 / 504 |
esophagus | 56% | 204.20 | 806 / 1445 | 80% | 5.22 | 146 / 183 |
uterus | 49% | 163.49 | 84 / 170 | 73% | 4.69 | 337 / 459 |
brain | 30% | 123.74 | 804 / 2642 | 89% | 9.65 | 626 / 705 |
kidney | 45% | 195.61 | 40 / 89 | 74% | 5.69 | 669 / 901 |
adrenal gland | 76% | 289.47 | 195 / 258 | 34% | 1.86 | 79 / 230 |
prostate | 69% | 291.84 | 168 / 245 | 41% | 1.62 | 205 / 502 |
lymph node | 0% | 0 | 0 / 0 | 100% | 38.52 | 29 / 29 |
peripheral blood | 100% | 7952.73 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 2822.76 | 241 / 241 | 0% | 0 | 0 / 0 |
pancreas | 15% | 42.32 | 50 / 328 | 83% | 6.95 | 148 / 178 |
adipose | 98% | 989.88 | 1175 / 1204 | 0% | 0 | 0 / 0 |
thymus | 48% | 181.26 | 311 / 653 | 45% | 2.76 | 274 / 605 |
ovary | 25% | 73.84 | 45 / 180 | 66% | 3.25 | 283 / 430 |
tonsil | 0% | 0 | 0 / 0 | 87% | 7.36 | 39 / 45 |
skin | 18% | 51.36 | 330 / 1809 | 60% | 5.20 | 281 / 472 |
liver | 38% | 142.73 | 85 / 226 | 31% | 1.56 | 127 / 406 |
blood vessel | 62% | 360.69 | 826 / 1335 | 0% | 0 | 0 / 0 |
heart | 39% | 170.45 | 333 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 13% | 0.51 | 10 / 80 |
muscle | 2% | 4.72 | 18 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002820 | Biological process | negative regulation of adaptive immune response |
GO_0050732 | Biological process | negative regulation of peptidyl-tyrosine phosphorylation |
GO_0050869 | Biological process | negative regulation of B cell activation |
GO_0001726 | Cellular component | ruffle |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0001784 | Molecular function | phosphotyrosine residue binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | SAMSN1 |
Protein name | SAM domain-containing protein SAMSN-1 (Hematopoietic adaptor containing SH3 and SAM domains 1) (Nash1) (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) SAM domain, SH3 domain and nuclear localization signals 1 |
Synonyms | HACS1 |
Description | FUNCTION: Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation (By similarity). . |
Accessions | Q9NSI8 S6FRS6 ENST00000285670.7 [Q9NSI8-3] ENST00000400564.5 [Q9NSI8-2] ENST00000619120.4 S6G369 ENST00000647101.1 S6G0C9 A0A2R8Y4K8 ENST00000400566.6 [Q9NSI8-1] |