PITPNB | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	34 studies	28% ± 10%	Explore
smooth muscle cell	22 studies	23% ± 5%	Explore
fibroblast	22 studies	25% ± 8%	Explore
pericyte	20 studies	24% ± 10%	Explore
endothelial cell of lymphatic vessel	13 studies	27% ± 8%	Explore
endothelial cell of vascular tree	11 studies	24% ± 10%	Explore
natural killer cell	10 studies	17% ± 2%	Explore
basal cell	10 studies	30% ± 14%	Explore
adipocyte	10 studies	24% ± 7%	Explore
astrocyte	10 studies	27% ± 10%	Explore
macrophage	9 studies	24% ± 9%	Explore
oligodendrocyte precursor cell	9 studies	26% ± 11%	Explore
capillary endothelial cell	8 studies	21% ± 6%	Explore
microglial cell	8 studies	25% ± 7%	Explore
endothelial cell of artery	8 studies	22% ± 4%	Explore
vein endothelial cell	8 studies	28% ± 12%	Explore
naive B cell	7 studies	18% ± 2%	Explore
myeloid cell	7 studies	22% ± 4%	Explore
epithelial cell	7 studies	38% ± 21%	Explore
dendritic cell	7 studies	21% ± 7%	Explore
myofibroblast cell	6 studies	27% ± 8%	Explore
connective tissue cell	6 studies	21% ± 6%	Explore
GABAergic neuron	6 studies	33% ± 14%	Explore
oligodendrocyte	6 studies	25% ± 5%	Explore
B cell	5 studies	21% ± 4%	Explore
neuron	5 studies	37% ± 12%	Explore
glutamatergic neuron	5 studies	46% ± 20%	Explore
cardiac muscle cell	5 studies	23% ± 3%	Explore
lymphocyte	5 studies	23% ± 5%	Explore
type I pneumocyte	5 studies	22% ± 6%	Explore
leukocyte	4 studies	20% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	16% ± 0%	Explore
plasma cell	4 studies	31% ± 10%	Explore
retinal pigment epithelial cell	4 studies	25% ± 8%	Explore
ciliated cell	4 studies	32% ± 9%	Explore
CD8-positive, alpha-beta T cell	4 studies	17% ± 1%	Explore
club cell	4 studies	24% ± 6%	Explore
T cell	4 studies	20% ± 3%	Explore
goblet cell	4 studies	27% ± 15%	Explore
interneuron	4 studies	36% ± 18%	Explore
classical monocyte	3 studies	18% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
CD4-positive, alpha-beta T cell	3 studies	20% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	16% ± 1%	Explore
precursor B cell	3 studies	19% ± 1%	Explore
mesothelial cell	3 studies	24% ± 2%	Explore
mononuclear phagocyte	3 studies	21% ± 4%	Explore
secretory cell	3 studies	24% ± 9%	Explore
memory B cell	3 studies	18% ± 3%	Explore
regulatory T cell	3 studies	18% ± 2%	Explore
cholangiocyte	3 studies	44% ± 23%	Explore
hepatocyte	3 studies	54% ± 27%	Explore
muscle cell	3 studies	31% ± 6%	Explore
type II pneumocyte	3 studies	22% ± 3%	Explore
abnormal cell	3 studies	28% ± 14%	Explore
adventitial cell	3 studies	20% ± 2%	Explore
alveolar macrophage	3 studies	26% ± 8%	Explore
monocyte	3 studies	25% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	16% ± 0%	Explore
transit amplifying cell	3 studies	40% ± 26%	Explore
mast cell	3 studies	18% ± 2%	Explore
plasmacytoid dendritic cell	3 studies	22% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	10 studies	30% ± 15%	Explore
lung	7 studies	24% ± 7%	Explore
heart	5 studies	21% ± 3%	Explore
peripheral blood	4 studies	20% ± 4%	Explore
liver	4 studies	30% ± 14%	Explore
intestine	4 studies	20% ± 5%	Explore
adipose	3 studies	25% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	6766.14	21 / 21	100%	51.49	504 / 504
esophagus	100%	6458.08	1445 / 1445	100%	60.88	183 / 183
pancreas	100%	2190.16	328 / 328	100%	48.07	178 / 178
prostate	100%	4084.48	245 / 245	100%	35.80	502 / 502
stomach	100%	4151.71	359 / 359	100%	47.45	286 / 286
uterus	100%	4425.99	170 / 170	100%	61.08	459 / 459
breast	100%	4832.42	459 / 459	100%	49.60	1116 / 1118
intestine	100%	5739.73	966 / 966	100%	48.88	526 / 527
ovary	100%	3988.01	180 / 180	100%	34.21	429 / 430
lung	100%	4532.04	577 / 578	100%	54.85	1154 / 1155
brain	99%	3184.86	2623 / 2642	100%	48.39	705 / 705
liver	100%	3602.90	226 / 226	99%	33.32	403 / 406
thymus	100%	3676.10	652 / 653	99%	32.57	601 / 605
kidney	100%	2969.75	89 / 89	99%	33.66	892 / 901
skin	100%	4493.80	1808 / 1809	99%	54.48	466 / 472
adrenal gland	100%	3139.73	258 / 258	95%	34.96	219 / 230
adipose	100%	5545.30	1204 / 1204	0%	0	0 / 0
blood vessel	100%	8997.02	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	47.21	29 / 29
spleen	100%	3451.59	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	62.35	45 / 45
ureter	0%	0	0 / 0	100%	25.49	1 / 1
heart	97%	2790.96	836 / 861	0%	0	0 / 0
muscle	91%	1691.32	733 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	91%	23.63	73 / 80
peripheral blood	69%	2238.70	639 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006997	Biological process	nucleus organization
GO_0120009	Biological process	intermembrane lipid transfer
GO_0006890	Biological process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0006629	Biological process	lipid metabolic process
GO_0015914	Biological process	phospholipid transport
GO_0000139	Cellular component	Golgi membrane
GO_0005737	Cellular component	cytoplasm
GO_0005794	Cellular component	Golgi apparatus
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0008526	Molecular function	phosphatidylinositol transfer activity
GO_0120019	Molecular function	phosphatidylcholine transfer activity
GO_0140338	Molecular function	sphingomyelin transfer activity
GO_0031210	Molecular function	phosphatidylcholine binding
GO_0005515	Molecular function	protein binding
GO_0008525	Molecular function	phosphatidylcholine transporter activity
GO_0035091	Molecular function	phosphatidylinositol binding

IV. Literature review

[source]

Gene name	PITPNB
Protein name	Phosphatidylinositol transfer protein beta isoform Phosphatidylinositol transfer protein beta isoform (PI-TP-beta) (PtdIns transfer protein beta) (PtdInsTP beta)
Synonyms
Description	FUNCTION: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes . Also catalyzes the transfer of sphingomyelin (By similarity). Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function . .
Accessions	ENST00000436663.1 ENST00000335272.10 [P48739-1] ENST00000415296.5 ENST00000320996.14 [P48739-2] ENST00000634017.1 [P48739-3] P48739 B3KYB6 B3KYB7

PITPNB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review