PARP8 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	36 studies	35% ± 15%	Explore
CD8-positive, alpha-beta T cell	31 studies	34% ± 15%	Explore
T cell	24 studies	36% ± 18%	Explore
CD4-positive, alpha-beta T cell	24 studies	32% ± 20%	Explore
mature NK T cell	19 studies	35% ± 12%	Explore
mucosal invariant T cell	16 studies	49% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	44% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	37% ± 12%	Explore
gamma-delta T cell	15 studies	38% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	47% ± 20%	Explore
oligodendrocyte precursor cell	12 studies	36% ± 16%	Explore
macrophage	12 studies	40% ± 20%	Explore
regulatory T cell	12 studies	26% ± 11%	Explore
GABAergic neuron	11 studies	37% ± 24%	Explore
microglial cell	11 studies	40% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	45% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	25% ± 7%	Explore
glutamatergic neuron	10 studies	53% ± 23%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	30% ± 18%	Explore
innate lymphoid cell	8 studies	40% ± 17%	Explore
B cell	7 studies	28% ± 10%	Explore
astrocyte	7 studies	31% ± 18%	Explore
endothelial cell	7 studies	31% ± 15%	Explore
myeloid cell	7 studies	31% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	29% ± 5%	Explore
leukocyte	6 studies	49% ± 29%	Explore
interneuron	6 studies	52% ± 22%	Explore
naive B cell	6 studies	19% ± 2%	Explore
dendritic cell	6 studies	29% ± 7%	Explore
ciliated cell	6 studies	22% ± 8%	Explore
fibroblast	6 studies	22% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	24% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	29% ± 7%	Explore
monocyte	5 studies	31% ± 6%	Explore
type I pneumocyte	5 studies	26% ± 5%	Explore
type II pneumocyte	5 studies	26% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	43% ± 22%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	21% ± 8%	Explore
classical monocyte	4 studies	25% ± 7%	Explore
neuron	4 studies	32% ± 5%	Explore
epithelial cell	4 studies	35% ± 11%	Explore
lymphocyte	4 studies	65% ± 23%	Explore
club cell	4 studies	26% ± 7%	Explore
basal cell	4 studies	31% ± 20%	Explore
pericyte	4 studies	23% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	28% ± 10%	Explore
exhausted T cell	3 studies	27% ± 6%	Explore
GABAergic interneuron	3 studies	36% ± 1%	Explore
glycinergic amacrine cell	3 studies	21% ± 4%	Explore
CD4-positive helper T cell	3 studies	42% ± 7%	Explore
alveolar macrophage	3 studies	36% ± 6%	Explore
respiratory goblet cell	3 studies	36% ± 10%	Explore
T follicular helper cell	3 studies	29% ± 8%	Explore
group 3 innate lymphoid cell	3 studies	23% ± 5%	Explore
smooth muscle cell	3 studies	17% ± 2%	Explore
double negative thymocyte	3 studies	32% ± 15%	Explore
mural cell	3 studies	40% ± 31%	Explore
mucus secreting cell	3 studies	28% ± 3%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	25% ± 10%	Explore
brain	12 studies	37% ± 21%	Explore
lung	8 studies	23% ± 7%	Explore
liver	3 studies	22% ± 4%	Explore
adipose	3 studies	22% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	5624.37	653 / 653	100%	20.84	605 / 605
prostate	100%	2003.96	244 / 245	100%	14.65	502 / 502
ovary	99%	1287.97	179 / 180	98%	10.03	422 / 430
lung	100%	3443.69	578 / 578	97%	10.67	1120 / 1155
esophagus	99%	1163.47	1424 / 1445	98%	8.68	180 / 183
adrenal gland	100%	1915.67	258 / 258	96%	8.67	221 / 230
intestine	99%	1813.17	959 / 966	95%	7.95	503 / 527
kidney	97%	1223.85	86 / 89	98%	12.07	881 / 901
stomach	100%	2287.79	359 / 359	94%	8.66	270 / 286
pancreas	95%	1010.83	311 / 328	98%	13.16	174 / 178
uterus	100%	1015.37	170 / 170	92%	7.70	421 / 459
breast	100%	1421.27	457 / 459	90%	8.75	1004 / 1118
bladder	95%	1558.71	20 / 21	94%	7.96	474 / 504
brain	84%	887.27	2208 / 2642	100%	10.60	703 / 705
skin	97%	986.41	1761 / 1809	76%	7.12	358 / 472
liver	88%	653.23	199 / 226	70%	4.10	283 / 406
lymph node	0%	0	0 / 0	100%	12.87	29 / 29
spleen	100%	6612.85	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	4.01	1 / 1
peripheral blood	100%	6038.95	928 / 929	0%	0	0 / 0
adipose	100%	1823.15	1200 / 1204	0%	0	0 / 0
blood vessel	99%	1979.71	1327 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	8.07	42 / 45
heart	68%	472.61	588 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	46%	2.80	37 / 80
muscle	3%	18.15	25 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0