NCOA7 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	41 studies	39% ± 13%	Explore
fibroblast	23 studies	30% ± 15%	Explore
basal cell	19 studies	34% ± 13%	Explore
natural killer cell	16 studies	19% ± 3%	Explore
oligodendrocyte	15 studies	58% ± 15%	Explore
epithelial cell	15 studies	31% ± 16%	Explore
endothelial cell of vascular tree	14 studies	40% ± 14%	Explore
vein endothelial cell	13 studies	40% ± 19%	Explore
ciliated cell	13 studies	37% ± 17%	Explore
endothelial cell of lymphatic vessel	11 studies	22% ± 7%	Explore
type I pneumocyte	11 studies	45% ± 15%	Explore
type II pneumocyte	11 studies	42% ± 15%	Explore
glutamatergic neuron	11 studies	49% ± 24%	Explore
mucosal invariant T cell	11 studies	20% ± 4%	Explore
gamma-delta T cell	11 studies	20% ± 4%	Explore
club cell	10 studies	36% ± 16%	Explore
microglial cell	10 studies	29% ± 10%	Explore
macrophage	10 studies	29% ± 13%	Explore
secretory cell	10 studies	42% ± 14%	Explore
adipocyte	9 studies	34% ± 11%	Explore
CD4-positive, alpha-beta T cell	8 studies	22% ± 7%	Explore
neuron	8 studies	48% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	19% ± 4%	Explore
pericyte	7 studies	26% ± 6%	Explore
GABAergic neuron	7 studies	46% ± 18%	Explore
B cell	6 studies	18% ± 3%	Explore
T cell	6 studies	25% ± 9%	Explore
ionocyte	6 studies	50% ± 15%	Explore
leukocyte	6 studies	21% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	18% ± 2%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	19% ± 3%	Explore
astrocyte	6 studies	30% ± 13%	Explore
oligodendrocyte precursor cell	6 studies	26% ± 9%	Explore
interneuron	6 studies	53% ± 28%	Explore
mature NK T cell	5 studies	20% ± 4%	Explore
capillary endothelial cell	5 studies	43% ± 14%	Explore
endothelial cell of artery	5 studies	21% ± 5%	Explore
retinal ganglion cell	5 studies	60% ± 23%	Explore
kidney loop of Henle epithelial cell	5 studies	27% ± 9%	Explore
renal alpha-intercalated cell	5 studies	40% ± 10%	Explore
lymphocyte	5 studies	25% ± 8%	Explore
Mueller cell	5 studies	38% ± 5%	Explore
dendritic cell	5 studies	30% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 3%	Explore
duct epithelial cell	4 studies	29% ± 12%	Explore
CD8-positive, alpha-beta T cell	4 studies	21% ± 6%	Explore
conventional dendritic cell	4 studies	21% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	22% ± 4%	Explore
glomerular endothelial cell	4 studies	43% ± 5%	Explore
plasma cell	4 studies	26% ± 9%	Explore
myeloid cell	4 studies	26% ± 6%	Explore
respiratory goblet cell	4 studies	38% ± 17%	Explore
T follicular helper cell	4 studies	16% ± 1%	Explore
innate lymphoid cell	4 studies	31% ± 12%	Explore
hematopoietic stem cell	4 studies	26% ± 5%	Explore
plasmacytoid dendritic cell	4 studies	25% ± 10%	Explore
GABAergic interneuron	3 studies	23% ± 5%	Explore
brush cell	3 studies	38% ± 24%	Explore
progenitor cell	3 studies	26% ± 7%	Explore
mesothelial cell	3 studies	29% ± 10%	Explore
ON-bipolar cell	3 studies	32% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	19% ± 2%	Explore
mast cell	3 studies	21% ± 4%	Explore
luminal cell of prostate epithelium	3 studies	23% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	22% ± 7%	Explore
pancreatic ductal cell	3 studies	50% ± 21%	Explore
intestinal crypt stem cell	3 studies	20% ± 2%	Explore
adventitial cell	3 studies	25% ± 4%	Explore
mucus secreting cell	3 studies	36% ± 21%	Explore
alveolar macrophage	3 studies	20% ± 4%	Explore
monocyte	3 studies	24% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	38% ± 4%	Explore
transit amplifying cell	3 studies	24% ± 11%	Explore
smooth muscle cell	3 studies	19% ± 4%	Explore
granule cell	3 studies	37% ± 3%	Explore
myoepithelial cell	3 studies	26% ± 6%	Explore
progenitor cell of mammary luminal epithelium	3 studies	26% ± 8%	Explore
epithelial cell of proximal tubule	3 studies	23% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	15 studies	43% ± 21%	Explore
lung	13 studies	28% ± 15%	Explore
eye	7 studies	24% ± 9%	Explore
peripheral blood	5 studies	18% ± 2%	Explore
kidney	5 studies	20% ± 4%	Explore
adipose	4 studies	32% ± 9%	Explore
uterus	3 studies	30% ± 9%	Explore
breast	3 studies	22% ± 5%	Explore
prostate	3 studies	18% ± 3%	Explore
intestine	3 studies	19% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2821.14	1439 / 1445	100%	59.60	183 / 183
lung	100%	4709.55	576 / 578	100%	55.70	1152 / 1155
intestine	100%	2663.58	966 / 966	98%	53.59	518 / 527
stomach	98%	2021.71	353 / 359	99%	55.69	283 / 286
adrenal gland	100%	5698.59	258 / 258	94%	42.34	216 / 230
uterus	99%	2313.34	168 / 170	95%	43.86	434 / 459
kidney	100%	4659.08	89 / 89	92%	28.51	825 / 901
ovary	99%	1725.74	179 / 180	92%	20.97	396 / 430
bladder	100%	2580.52	21 / 21	87%	31.83	440 / 504
breast	100%	4938.29	459 / 459	87%	23.90	974 / 1118
brain	98%	3942.08	2586 / 2642	87%	14.43	615 / 705
thymus	100%	2754.27	652 / 653	84%	23.15	510 / 605
pancreas	82%	1186.75	270 / 328	99%	33.23	176 / 178
skin	97%	1953.65	1752 / 1809	75%	12.90	355 / 472
prostate	96%	2503.76	234 / 245	71%	15.68	354 / 502
liver	89%	2245.39	202 / 226	66%	14.76	269 / 406
adipose	100%	6271.42	1204 / 1204	0%	0	0 / 0
spleen	100%	2319.62	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	7.53	1 / 1
blood vessel	100%	2650.86	1331 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	37.81	42 / 45
lymph node	0%	0	0 / 0	83%	13.71	24 / 29
heart	71%	1253.56	613 / 861	0%	0	0 / 0
peripheral blood	59%	1329.00	544 / 929	0%	0	0 / 0
muscle	50%	552.19	403 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	19%	1.88	15 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1902083	Biological process	negative regulation of peptidyl-cysteine S-nitrosylation
GO_0006979	Biological process	response to oxidative stress
GO_1900408	Biological process	negative regulation of cellular response to oxidative stress
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005634	Cellular component	nucleus
GO_0016922	Molecular function	nuclear receptor binding
GO_0030374	Molecular function	nuclear receptor coactivator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	NCOA7
Protein name	NCOA7-AS Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1) NCOA7 protein Nuclear receptor coactivator 7
Synonyms	ERAP140 ESNA1 Nbla10993 Nbla00052
Description	FUNCTION: Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA. .
Accessions	ENST00000453302.5 Q5TF98 Q8N4U9 ENST00000428318.1 Q5TF96 ENST00000444128.2 H0Y5F6 ENST00000392477.7 [Q8NI08-1] H0Y6T0 ENST00000417494.5 Q5TF97 Q6PK00 ENST00000419660.1 ENST00000438495.6 [Q8NI08-5] Q8NI08 ENST00000229634.13 [Q8NI08-7] ENST00000368357.7 [Q8NI08-1]

NCOA7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review