MPC1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
non-classical monocyte	17 studies	29% ± 13%	Explore
macrophage	13 studies	24% ± 9%	Explore
pericyte	13 studies	22% ± 5%	Explore
endothelial cell	12 studies	23% ± 6%	Explore
oligodendrocyte	12 studies	28% ± 11%	Explore
astrocyte	11 studies	31% ± 14%	Explore
smooth muscle cell	11 studies	23% ± 7%	Explore
fibroblast	11 studies	26% ± 13%	Explore
epithelial cell	10 studies	36% ± 14%	Explore
plasma cell	8 studies	31% ± 12%	Explore
classical monocyte	8 studies	25% ± 10%	Explore
conventional dendritic cell	8 studies	29% ± 17%	Explore
kidney loop of Henle epithelial cell	8 studies	56% ± 21%	Explore
ciliated cell	7 studies	30% ± 11%	Explore
renal alpha-intercalated cell	7 studies	61% ± 23%	Explore
natural killer cell	7 studies	21% ± 3%	Explore
connective tissue cell	7 studies	20% ± 6%	Explore
CD4-positive, alpha-beta T cell	6 studies	16% ± 2%	Explore
epithelial cell of proximal tubule	6 studies	30% ± 9%	Explore
myeloid cell	6 studies	21% ± 9%	Explore
monocyte	6 studies	20% ± 4%	Explore
cardiac muscle cell	6 studies	38% ± 8%	Explore
goblet cell	6 studies	25% ± 10%	Explore
plasmablast	5 studies	38% ± 21%	Explore
ionocyte	5 studies	31% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	50% ± 21%	Explore
myofibroblast cell	5 studies	20% ± 3%	Explore
endothelial cell of lymphatic vessel	5 studies	21% ± 6%	Explore
type I pneumocyte	5 studies	25% ± 9%	Explore
adipocyte	5 studies	25% ± 5%	Explore
regulatory T cell	5 studies	18% ± 1%	Explore
hepatocyte	5 studies	53% ± 20%	Explore
glutamatergic neuron	5 studies	42% ± 20%	Explore
oligodendrocyte precursor cell	5 studies	30% ± 10%	Explore
basal cell	5 studies	26% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	20% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	18% ± 1%	Explore
mature NK T cell	4 studies	17% ± 1%	Explore
retinal ganglion cell	4 studies	51% ± 27%	Explore
renal principal cell	4 studies	44% ± 19%	Explore
enterocyte	4 studies	24% ± 5%	Explore
retina horizontal cell	4 studies	38% ± 13%	Explore
type II pneumocyte	4 studies	28% ± 17%	Explore
Mueller cell	4 studies	32% ± 12%	Explore
CD8-positive, alpha-beta T cell	4 studies	19% ± 4%	Explore
GABAergic neuron	4 studies	43% ± 16%	Explore
dendritic cell	4 studies	38% ± 18%	Explore
gamma-delta T cell	4 studies	24% ± 12%	Explore
mast cell	4 studies	17% ± 1%	Explore
interneuron	4 studies	31% ± 18%	Explore
plasmacytoid dendritic cell	4 studies	27% ± 7%	Explore
secretory cell	3 studies	21% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
mononuclear phagocyte	3 studies	28% ± 10%	Explore
hematopoietic precursor cell	3 studies	24% ± 3%	Explore
neuron	3 studies	32% ± 12%	Explore
abnormal cell	3 studies	32% ± 9%	Explore
progenitor cell	3 studies	26% ± 4%	Explore
amacrine cell	3 studies	37% ± 14%	Explore
retinal cone cell	3 studies	44% ± 15%	Explore
retinal pigment epithelial cell	3 studies	35% ± 10%	Explore
retinal rod cell	3 studies	26% ± 7%	Explore
alveolar macrophage	3 studies	22% ± 1%	Explore
OFF-bipolar cell	3 studies	25% ± 10%	Explore
ON-bipolar cell	3 studies	28% ± 8%	Explore
rod bipolar cell	3 studies	30% ± 8%	Explore
transit amplifying cell	3 studies	18% ± 1%	Explore
microglial cell	3 studies	17% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
kidney	9 studies	24% ± 8%	Explore
brain	9 studies	32% ± 16%	Explore
eye	7 studies	26% ± 10%	Explore
peripheral blood	6 studies	22% ± 5%	Explore
lung	6 studies	24% ± 4%	Explore
liver	6 studies	30% ± 13%	Explore
intestine	5 studies	23% ± 7%	Explore
heart	4 studies	20% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	6878.66	226 / 226	100%	123.54	406 / 406
stomach	100%	2622.27	359 / 359	100%	65.99	286 / 286
brain	100%	3593.70	2641 / 2642	100%	176.98	705 / 705
kidney	100%	5123.44	89 / 89	100%	110.64	900 / 901
intestine	100%	2408.71	966 / 966	100%	68.26	526 / 527
ovary	100%	1674.35	180 / 180	100%	51.53	429 / 430
pancreas	100%	1376.93	327 / 328	100%	49.40	178 / 178
thymus	100%	2606.04	653 / 653	100%	76.54	603 / 605
breast	100%	2245.16	459 / 459	99%	58.57	1112 / 1118
prostate	100%	1666.09	244 / 245	100%	66.30	500 / 502
uterus	100%	1635.13	170 / 170	99%	56.77	454 / 459
esophagus	100%	1897.60	1445 / 1445	99%	50.79	181 / 183
adrenal gland	99%	1352.82	256 / 258	100%	63.71	229 / 230
lung	99%	1999.09	573 / 578	99%	56.90	1147 / 1155
bladder	100%	1707.81	21 / 21	98%	51.30	495 / 504
skin	100%	1537.69	1803 / 1809	96%	49.55	455 / 472
adipose	100%	2338.61	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	72.54	29 / 29
spleen	100%	1549.41	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	54.60	45 / 45
muscle	100%	3798.48	802 / 803	0%	0	0 / 0
blood vessel	100%	2411.75	1331 / 1335	0%	0	0 / 0
heart	99%	8610.02	851 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	77.16	79 / 80
peripheral blood	64%	805.41	594 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0006850	Biological process	mitochondrial pyruvate transmembrane transport
GO_0008150	Biological process	biological_process
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0098800	Cellular component	inner mitochondrial membrane protein complex
GO_0005739	Cellular component	mitochondrion
GO_0050833	Molecular function	pyruvate transmembrane transporter activity
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function

IV. Literature review

[source]

Gene name	MPC1
Protein name	Mitochondrial pyruvate carrier 1 (Brain protein 44-like protein) Mitochondrial pyruvate carrier
Synonyms	BRP44L HSPC040 PNAS-115 CGI-129
Description	FUNCTION: Mediates the uptake of pyruvate into mitochondria. . FUNCTION: Mediates the uptake of pyruvate into mitochondria. .
Accessions	A0A087WVZ0 ENST00000621630.1 ENST00000360961.11 Q9Y5U8

MPC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review