MARCKSL1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	35 studies	52% ± 23%	Explore
B cell	31 studies	34% ± 15%	Explore
fibroblast	23 studies	41% ± 21%	Explore
endothelial cell of lymphatic vessel	22 studies	63% ± 21%	Explore
conventional dendritic cell	19 studies	30% ± 12%	Explore
dendritic cell	17 studies	54% ± 28%	Explore
memory B cell	17 studies	29% ± 7%	Explore
naive B cell	16 studies	32% ± 9%	Explore
pericyte	16 studies	49% ± 26%	Explore
non-classical monocyte	15 studies	35% ± 12%	Explore
epithelial cell	15 studies	52% ± 25%	Explore
oligodendrocyte	14 studies	46% ± 17%	Explore
connective tissue cell	14 studies	55% ± 25%	Explore
smooth muscle cell	14 studies	47% ± 25%	Explore
CD4-positive, alpha-beta T cell	13 studies	28% ± 15%	Explore
capillary endothelial cell	13 studies	40% ± 22%	Explore
basal cell	13 studies	38% ± 17%	Explore
T cell	12 studies	28% ± 25%	Explore
plasmacytoid dendritic cell	12 studies	34% ± 13%	Explore
vein endothelial cell	12 studies	51% ± 23%	Explore
oligodendrocyte precursor cell	11 studies	50% ± 22%	Explore
endothelial cell of vascular tree	11 studies	44% ± 13%	Explore
secretory cell	10 studies	40% ± 15%	Explore
myofibroblast cell	10 studies	61% ± 26%	Explore
endothelial cell of artery	10 studies	40% ± 26%	Explore
classical monocyte	9 studies	29% ± 11%	Explore
astrocyte	9 studies	31% ± 15%	Explore
goblet cell	9 studies	51% ± 22%	Explore
monocyte	8 studies	25% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	22% ± 8%	Explore
abnormal cell	8 studies	48% ± 20%	Explore
CD8-positive, alpha-beta T cell	8 studies	27% ± 13%	Explore
brush cell	8 studies	81% ± 9%	Explore
progenitor cell	7 studies	69% ± 26%	Explore
neuron	7 studies	68% ± 29%	Explore
enteroendocrine cell	6 studies	72% ± 19%	Explore
intestinal crypt stem cell	6 studies	57% ± 23%	Explore
mesothelial cell	6 studies	64% ± 17%	Explore
precursor B cell	6 studies	50% ± 8%	Explore
natural killer cell	6 studies	20% ± 5%	Explore
hematopoietic precursor cell	5 studies	40% ± 20%	Explore
leukocyte	5 studies	27% ± 3%	Explore
transit amplifying cell	5 studies	44% ± 19%	Explore
macrophage	5 studies	26% ± 13%	Explore
hematopoietic stem cell	5 studies	26% ± 6%	Explore
pro-B cell	5 studies	46% ± 13%	Explore
myeloid cell	5 studies	38% ± 7%	Explore
immature B cell	5 studies	48% ± 16%	Explore
amacrine cell	5 studies	45% ± 29%	Explore
GABAergic neuron	5 studies	38% ± 19%	Explore
interneuron	5 studies	50% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	23% ± 11%	Explore
club cell	4 studies	44% ± 18%	Explore
ionocyte	4 studies	51% ± 18%	Explore
mononuclear phagocyte	4 studies	29% ± 7%	Explore
glomerular endothelial cell	4 studies	32% ± 10%	Explore
renal alpha-intercalated cell	4 studies	47% ± 26%	Explore
GABAergic amacrine cell	4 studies	34% ± 12%	Explore
glycinergic amacrine cell	4 studies	28% ± 13%	Explore
erythroblast	4 studies	35% ± 20%	Explore
ciliated cell	4 studies	32% ± 10%	Explore
germinal center B cell	4 studies	69% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	22% ± 11%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	76% ± 11%	Explore
mature NK T cell	4 studies	17% ± 1%	Explore
monocyte-derived dendritic cell	4 studies	48% ± 20%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	50% ± 23%	Explore
deuterosomal cell	3 studies	32% ± 7%	Explore
duct epithelial cell	3 studies	34% ± 1%	Explore
respiratory goblet cell	3 studies	36% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	20% ± 6%	Explore
plasmablast	3 studies	39% ± 23%	Explore
enterocyte	3 studies	29% ± 17%	Explore
neural crest cell	3 studies	82% ± 21%	Explore
retinal ganglion cell	3 studies	45% ± 17%	Explore
neuroendocrine cell	3 studies	65% ± 27%	Explore
mucus secreting cell	3 studies	42% ± 16%	Explore
lymphocyte	3 studies	58% ± 23%	Explore
Mueller cell	3 studies	57% ± 12%	Explore
T follicular helper cell	3 studies	23% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	28% ± 10%	Explore
gamma-delta T cell	3 studies	44% ± 34%	Explore
myoepithelial cell	3 studies	60% ± 5%	Explore
luminal cell of prostate epithelium	3 studies	45% ± 7%	Explore
pancreatic ductal cell	3 studies	51% ± 12%	Explore
erythrocyte	3 studies	32% ± 6%	Explore
melanocyte	3 studies	30% ± 10%	Explore
glutamatergic neuron	3 studies	42% ± 26%	Explore
plasma cell	3 studies	35% ± 5%	Explore
progenitor cell of mammary luminal epithelium	3 studies	67% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	11 studies	32% ± 8%	Explore
lung	10 studies	40% ± 21%	Explore
peripheral blood	9 studies	23% ± 13%	Explore
intestine	8 studies	44% ± 21%	Explore
eye	7 studies	24% ± 9%	Explore
kidney	4 studies	35% ± 21%	Explore
bone marrow	4 studies	24% ± 9%	Explore
uterus	4 studies	40% ± 16%	Explore
breast	4 studies	45% ± 11%	Explore
liver	4 studies	20% ± 4%	Explore
lymph node	4 studies	43% ± 21%	Explore
prostate	3 studies	29% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	17223.91	2641 / 2642	100%	1382.62	704 / 705
ovary	100%	26837.05	180 / 180	100%	829.79	428 / 430
thymus	100%	8467.23	652 / 653	97%	710.08	587 / 605
prostate	96%	4863.62	236 / 245	100%	1058.05	500 / 502
breast	91%	4608.01	419 / 459	99%	905.04	1104 / 1118
uterus	95%	4875.49	162 / 170	89%	585.09	409 / 459
lung	88%	2910.88	508 / 578	91%	434.20	1056 / 1155
stomach	81%	3765.81	289 / 359	99%	668.19	282 / 286
intestine	61%	3359.37	591 / 966	99%	725.25	523 / 527
bladder	67%	2096.24	14 / 21	92%	595.59	465 / 504
skin	50%	1265.54	910 / 1809	97%	947.43	459 / 472
adrenal gland	100%	4288.28	258 / 258	28%	91.49	65 / 230
kidney	76%	2097.80	68 / 89	45%	107.38	401 / 901
pancreas	24%	506.55	78 / 328	95%	565.78	169 / 178
esophagus	20%	460.98	293 / 1445	84%	386.61	154 / 183
ureter	0%	0	0 / 0	100%	427.16	1 / 1
spleen	100%	4857.41	240 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	785.27	27 / 29
tonsil	0%	0	0 / 0	87%	299.76	39 / 45
adipose	85%	3123.98	1020 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	74%	234.74	59 / 80
liver	38%	900.61	85 / 226	35%	117.23	143 / 406
heart	57%	1839.97	490 / 861	0%	0	0 / 0
peripheral blood	52%	4781.24	485 / 929	0%	0	0 / 0
blood vessel	22%	715.47	296 / 1335	0%	0	0 / 0
muscle	1%	25.07	10 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007015	Biological process	actin filament organization
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0008283	Biological process	cell population proliferation
GO_0007417	Biological process	central nervous system development
GO_0070062	Cellular component	extracellular exosome
GO_0005856	Cellular component	cytoskeleton
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005516	Molecular function	calmodulin binding
GO_0051015	Molecular function	actin filament binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	MARCKSL1
Protein name	MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS)
Synonyms	MLP MRP
Description	FUNCTION: Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation . When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity). .
Accessions	ENST00000329421.8 P49006

MARCKSL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review