IFI27L2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	25 studies	28% ± 11%	Explore
fibroblast	24 studies	35% ± 13%	Explore
natural killer cell	23 studies	24% ± 8%	Explore
classical monocyte	23 studies	29% ± 10%	Explore
macrophage	19 studies	27% ± 10%	Explore
pericyte	19 studies	28% ± 11%	Explore
regulatory T cell	16 studies	24% ± 9%	Explore
B cell	15 studies	20% ± 5%	Explore
T cell	15 studies	22% ± 6%	Explore
non-classical monocyte	14 studies	26% ± 11%	Explore
smooth muscle cell	14 studies	27% ± 8%	Explore
endothelial cell	13 studies	27% ± 10%	Explore
connective tissue cell	13 studies	34% ± 14%	Explore
plasma cell	12 studies	32% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	26% ± 6%	Explore
monocyte	12 studies	29% ± 11%	Explore
conventional dendritic cell	12 studies	30% ± 14%	Explore
mature NK T cell	12 studies	23% ± 4%	Explore
basal cell	11 studies	29% ± 10%	Explore
gamma-delta T cell	11 studies	25% ± 5%	Explore
myofibroblast cell	10 studies	26% ± 8%	Explore
ciliated cell	10 studies	34% ± 14%	Explore
CD4-positive, alpha-beta T cell	10 studies	22% ± 5%	Explore
platelet	9 studies	33% ± 11%	Explore
endothelial cell of artery	9 studies	23% ± 6%	Explore
epithelial cell	9 studies	29% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	29% ± 11%	Explore
capillary endothelial cell	8 studies	22% ± 3%	Explore
memory B cell	8 studies	21% ± 4%	Explore
plasmacytoid dendritic cell	7 studies	22% ± 7%	Explore
myeloid cell	7 studies	27% ± 12%	Explore
mast cell	7 studies	17% ± 1%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	32% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	26% ± 7%	Explore
astrocyte	6 studies	33% ± 19%	Explore
goblet cell	6 studies	29% ± 12%	Explore
abnormal cell	6 studies	29% ± 16%	Explore
dendritic cell	6 studies	30% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	24% ± 8%	Explore
plasmablast	5 studies	41% ± 17%	Explore
retinal rod cell	5 studies	41% ± 18%	Explore
neuron	5 studies	46% ± 23%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	25% ± 11%	Explore
alveolar macrophage	4 studies	21% ± 3%	Explore
pancreatic A cell	4 studies	50% ± 8%	Explore
exhausted T cell	4 studies	47% ± 9%	Explore
retinal ganglion cell	4 studies	62% ± 25%	Explore
retinal cone cell	4 studies	62% ± 23%	Explore
megakaryocyte	4 studies	35% ± 9%	Explore
amacrine cell	4 studies	30% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	32% ± 7%	Explore
intermediate monocyte	4 studies	38% ± 14%	Explore
mucosal invariant T cell	4 studies	19% ± 4%	Explore
mononuclear phagocyte	4 studies	25% ± 9%	Explore
type B pancreatic cell	3 studies	39% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	21% ± 4%	Explore
glomerular endothelial cell	3 studies	28% ± 2%	Explore
IgG plasma cell	3 studies	21% ± 3%	Explore
intraepithelial lymphocyte	3 studies	25% ± 7%	Explore
Mueller cell	3 studies	38% ± 11%	Explore
oligodendrocyte	3 studies	22% ± 6%	Explore
endothelial cell of vascular tree	3 studies	27% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	28% ± 9%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 8%	Explore
glial cell	3 studies	31% ± 15%	Explore
T-helper 17 cell	3 studies	26% ± 0%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	23% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	24% ± 7%	Explore
lung	12 studies	27% ± 9%	Explore
intestine	6 studies	24% ± 12%	Explore
eye	6 studies	32% ± 17%	Explore
pancreas	4 studies	35% ± 12%	Explore
kidney	4 studies	25% ± 5%	Explore
uterus	4 studies	27% ± 7%	Explore
brain	3 studies	24% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1796.78	2640 / 2642	100%	127.47	703 / 705
adrenal gland	100%	2068.81	258 / 258	98%	136.38	225 / 230
skin	99%	1209.62	1799 / 1809	98%	83.29	464 / 472
uterus	100%	1161.85	170 / 170	95%	71.78	437 / 459
kidney	99%	838.80	88 / 89	96%	53.26	861 / 901
thymus	98%	691.89	641 / 653	96%	57.39	579 / 605
ovary	100%	1478.34	180 / 180	93%	38.63	402 / 430
lung	100%	1112.43	576 / 578	93%	45.10	1076 / 1155
esophagus	100%	1031.34	1441 / 1445	92%	37.90	169 / 183
intestine	100%	972.09	962 / 966	89%	36.16	471 / 527
bladder	100%	795.90	21 / 21	83%	44.68	417 / 504
breast	100%	864.38	457 / 459	83%	27.83	929 / 1118
stomach	79%	505.11	283 / 359	88%	30.90	253 / 286
pancreas	43%	157.25	141 / 328	96%	70.87	171 / 178
prostate	96%	681.20	236 / 245	40%	8.84	202 / 502
eye	0%	0	0 / 0	100%	119.12	80 / 80
lymph node	0%	0	0 / 0	100%	146.95	29 / 29
spleen	100%	1263.53	241 / 241	0%	0	0 / 0
heart	99%	1133.72	853 / 861	0%	0	0 / 0
adipose	99%	863.19	1191 / 1204	0%	0	0 / 0
blood vessel	98%	1033.29	1311 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	91.16	44 / 45
peripheral blood	88%	753.54	820 / 929	0%	0	0 / 0
liver	8%	29.65	18 / 226	39%	12.51	157 / 406
muscle	9%	27.36	74 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0006915	Biological process	apoptotic process
GO_0097190	Biological process	apoptotic signaling pathway
GO_0031966	Cellular component	mitochondrial membrane
GO_0005739	Cellular component	mitochondrion

IV. Literature review

[source]

Gene name	IFI27L2
Protein name	Family with sequence similarity 14, member A, isoform CRA_b (Interferon alpha inducible protein 27 like 2) (Interferon alpha-inducible protein 27-like protein 2) Interferon alpha-inducible protein 27-like protein 2 (Interferon-stimulated gene 12b protein) (ISG12(b)) (ISG12B) (Protein TLH29) (pIFI27-like protein)
Synonyms	hCG_22340 TLH29 FAM14A
Description	FUNCTION: Plays a role in the apoptotic process and has a pro-apoptotic activity. .
Accessions	A0A0B4J270 ENST00000626155.1 ENST00000619362.2 ENST00000556727.1 Q9H2X8 ENST00000238609.4

IFI27L2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review