HDDC2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	23 studies	25% ± 6%	Explore
fibroblast	14 studies	28% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	28% ± 6%	Explore
CD4-positive, alpha-beta T cell	10 studies	23% ± 6%	Explore
epithelial cell	10 studies	31% ± 20%	Explore
pericyte	10 studies	21% ± 7%	Explore
CD8-positive, alpha-beta T cell	10 studies	24% ± 7%	Explore
basal cell	9 studies	26% ± 13%	Explore
mature NK T cell	9 studies	22% ± 6%	Explore
smooth muscle cell	9 studies	22% ± 6%	Explore
B cell	8 studies	21% ± 8%	Explore
connective tissue cell	8 studies	23% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	21% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	23% ± 5%	Explore
myofibroblast cell	7 studies	22% ± 5%	Explore
astrocyte	7 studies	35% ± 21%	Explore
regulatory T cell	6 studies	19% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	19% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
kidney loop of Henle epithelial cell	5 studies	26% ± 5%	Explore
epithelial cell of proximal tubule	5 studies	22% ± 4%	Explore
T cell	5 studies	22% ± 4%	Explore
mesothelial cell	5 studies	29% ± 17%	Explore
abnormal cell	5 studies	24% ± 9%	Explore
ciliated cell	5 studies	33% ± 8%	Explore
gamma-delta T cell	5 studies	27% ± 19%	Explore
exhausted T cell	4 studies	21% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	21% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	28% ± 7%	Explore
retinal ganglion cell	4 studies	52% ± 28%	Explore
precursor B cell	4 studies	25% ± 7%	Explore
T follicular helper cell	4 studies	17% ± 2%	Explore
oligodendrocyte precursor cell	4 studies	34% ± 9%	Explore
hematopoietic precursor cell	3 studies	29% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	19% ± 2%	Explore
pancreatic A cell	3 studies	32% ± 0%	Explore
non-classical monocyte	3 studies	20% ± 3%	Explore
progenitor cell	3 studies	22% ± 4%	Explore
neural crest cell	3 studies	38% ± 12%	Explore
pro-B cell	3 studies	27% ± 4%	Explore
type II pneumocyte	3 studies	33% ± 18%	Explore
amacrine cell	3 studies	40% ± 11%	Explore
retina horizontal cell	3 studies	34% ± 10%	Explore
retinal pigment epithelial cell	3 studies	43% ± 21%	Explore
endothelial cell	3 studies	26% ± 7%	Explore
alveolar macrophage	3 studies	21% ± 1%	Explore
erythroblast	3 studies	29% ± 15%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
neuron	3 studies	34% ± 20%	Explore
macrophage	3 studies	32% ± 8%	Explore
GABAergic neuron	3 studies	31% ± 2%	Explore
glutamatergic neuron	3 studies	35% ± 6%	Explore
dendritic cell	3 studies	29% ± 10%	Explore
goblet cell	3 studies	26% ± 10%	Explore
intestinal crypt stem cell	3 studies	24% ± 3%	Explore
interneuron	3 studies	28% ± 9%	Explore
plasmacytoid dendritic cell	3 studies	20% ± 0%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	25% ± 8%	Explore
double negative thymocyte	3 studies	31% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	21% ± 7%	Explore
kidney	5 studies	16% ± 1%	Explore
eye	5 studies	23% ± 5%	Explore
lung	5 studies	29% ± 9%	Explore
brain	5 studies	25% ± 5%	Explore
intestine	4 studies	24% ± 12%	Explore
pancreas	3 studies	31% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	4823.68	2642 / 2642	100%	38.79	705 / 705
kidney	100%	2695.75	89 / 89	100%	26.57	901 / 901
ovary	100%	1968.63	180 / 180	100%	21.28	430 / 430
stomach	100%	1639.28	359 / 359	100%	18.19	286 / 286
thymus	100%	2237.85	653 / 653	100%	37.20	605 / 605
uterus	100%	1754.96	170 / 170	100%	27.93	459 / 459
breast	100%	2152.32	459 / 459	100%	25.74	1117 / 1118
skin	100%	2072.91	1807 / 1809	100%	34.49	472 / 472
esophagus	100%	1722.48	1443 / 1445	100%	20.08	183 / 183
intestine	100%	1763.58	966 / 966	100%	22.08	525 / 527
bladder	100%	1989.71	21 / 21	99%	21.22	501 / 504
prostate	100%	2011.33	244 / 245	100%	23.23	501 / 502
lung	99%	1630.52	574 / 578	100%	24.49	1154 / 1155
adrenal gland	100%	3975.90	258 / 258	99%	24.51	228 / 230
pancreas	98%	1162.34	323 / 328	100%	19.00	178 / 178
liver	62%	419.93	141 / 226	66%	7.19	269 / 406
adipose	100%	2185.58	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	29.95	29 / 29
muscle	100%	3573.75	803 / 803	0%	0	0 / 0
spleen	100%	1286.88	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	20.80	45 / 45
ureter	0%	0	0 / 0	100%	7.05	1 / 1
blood vessel	100%	2270.01	1332 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	27.37	79 / 80
heart	97%	2404.16	836 / 861	0%	0	0 / 0
peripheral blood	42%	748.20	394 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0002953	Molecular function	5'-deoxynucleotidase activity
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	HDDC2
Protein name	5'-deoxynucleotidase HDDC2 (EC 3.1.3.89) (HD domain-containing protein 2) (Hepatitis C virus NS5A-transactivated protein 2) (HCV NS5A-transactivated protein 2) HD domain containing 2
Synonyms	C6orf74 NS5ATP2 CGI-130
Description	FUNCTION: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP). .
Accessions	V9GZ04 ENST00000608295.5 ENST00000608284.1 Q7Z4H3 ENST00000609477.5 [Q7Z4H3-3] ENST00000318787.13 [Q7Z4H3-3] ENST00000398153.7 [Q7Z4H3-1] V9GYS5

HDDC2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review