Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 49 studies | 46% ± 19% | |
macrophage | 31 studies | 42% ± 24% | |
classical monocyte | 21 studies | 28% ± 11% | |
astrocyte | 20 studies | 61% ± 23% | |
fibroblast | 17 studies | 36% ± 16% | |
oligodendrocyte | 16 studies | 59% ± 18% | |
microglial cell | 16 studies | 71% ± 14% | |
oligodendrocyte precursor cell | 15 studies | 54% ± 20% | |
monocyte | 14 studies | 42% ± 27% | |
ciliated cell | 14 studies | 38% ± 19% | |
dendritic cell | 13 studies | 45% ± 23% | |
glutamatergic neuron | 13 studies | 68% ± 24% | |
conventional dendritic cell | 13 studies | 27% ± 12% | |
endothelial cell of artery | 13 studies | 36% ± 16% | |
mast cell | 13 studies | 44% ± 13% | |
vein endothelial cell | 13 studies | 38% ± 23% | |
type I pneumocyte | 12 studies | 50% ± 23% | |
smooth muscle cell | 12 studies | 32% ± 11% | |
capillary endothelial cell | 12 studies | 35% ± 18% | |
myeloid cell | 12 studies | 48% ± 21% | |
GABAergic neuron | 11 studies | 65% ± 17% | |
type II pneumocyte | 10 studies | 47% ± 22% | |
pericyte | 10 studies | 35% ± 13% | |
endothelial cell of vascular tree | 10 studies | 36% ± 21% | |
epithelial cell | 10 studies | 44% ± 19% | |
basal cell | 10 studies | 38% ± 21% | |
neuron | 9 studies | 54% ± 24% | |
adipocyte | 9 studies | 35% ± 11% | |
goblet cell | 8 studies | 29% ± 15% | |
endothelial cell of lymphatic vessel | 8 studies | 44% ± 15% | |
non-classical monocyte | 7 studies | 29% ± 11% | |
mononuclear phagocyte | 7 studies | 38% ± 22% | |
interneuron | 7 studies | 62% ± 24% | |
club cell | 7 studies | 46% ± 16% | |
alveolar macrophage | 7 studies | 46% ± 29% | |
retinal ganglion cell | 6 studies | 45% ± 21% | |
retina horizontal cell | 6 studies | 39% ± 21% | |
plasmacytoid dendritic cell | 6 studies | 22% ± 4% | |
amacrine cell | 5 studies | 51% ± 14% | |
mucus secreting cell | 5 studies | 41% ± 19% | |
respiratory goblet cell | 5 studies | 46% ± 23% | |
T cell | 5 studies | 35% ± 18% | |
connective tissue cell | 5 studies | 30% ± 10% | |
neutrophil | 5 studies | 38% ± 21% | |
CD4-positive, alpha-beta T cell | 4 studies | 22% ± 5% | |
hematopoietic precursor cell | 4 studies | 50% ± 26% | |
glial cell | 4 studies | 29% ± 7% | |
granule cell | 4 studies | 50% ± 21% | |
progenitor cell | 4 studies | 36% ± 16% | |
retinal pigment epithelial cell | 4 studies | 48% ± 21% | |
mesothelial cell | 4 studies | 35% ± 11% | |
lymphocyte | 4 studies | 27% ± 5% | |
Mueller cell | 4 studies | 38% ± 16% | |
hepatocyte | 4 studies | 60% ± 18% | |
hematopoietic stem cell | 4 studies | 32% ± 17% | |
megakaryocyte-erythroid progenitor cell | 4 studies | 55% ± 20% | |
enteroendocrine cell | 4 studies | 26% ± 9% | |
endothelial cell of sinusoid | 3 studies | 32% ± 13% | |
glomerular endothelial cell | 3 studies | 30% ± 6% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 53% ± 12% | |
GABAergic interneuron | 3 studies | 55% ± 8% | |
megakaryocyte | 3 studies | 51% ± 20% | |
platelet | 3 studies | 23% ± 4% | |
serous secreting cell | 3 studies | 27% ± 2% | |
tissue-resident macrophage | 3 studies | 34% ± 24% | |
GABAergic amacrine cell | 3 studies | 69% ± 11% | |
glycinergic amacrine cell | 3 studies | 47% ± 14% | |
secretory cell | 3 studies | 18% ± 1% | |
cholangiocyte | 3 studies | 61% ± 9% | |
neural progenitor cell | 3 studies | 45% ± 20% | |
ependymal cell | 3 studies | 63% ± 17% | |
leukocyte | 3 studies | 38% ± 25% | |
myofibroblast cell | 3 studies | 42% ± 18% | |
muscle cell | 3 studies | 23% ± 8% | |
erythroblast | 3 studies | 33% ± 14% | |
renal alpha-intercalated cell | 3 studies | 45% ± 16% | |
renal principal cell | 3 studies | 32% ± 14% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 18 studies | 63% ± 20% | |
lung | 12 studies | 34% ± 19% | |
liver | 5 studies | 34% ± 17% | |
heart | 4 studies | 27% ± 8% | |
eye | 4 studies | 40% ± 24% | |
kidney | 4 studies | 33% ± 12% | |
peripheral blood | 3 studies | 28% ± 2% | |
intestine | 3 studies | 21% ± 4% | |
adipose | 3 studies | 40% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5810.02 | 1445 / 1445 | 100% | 51.44 | 183 / 183 |
thymus | 100% | 5297.49 | 653 / 653 | 100% | 55.51 | 605 / 605 |
brain | 100% | 8342.72 | 2642 / 2642 | 100% | 72.62 | 703 / 705 |
prostate | 100% | 5159.19 | 244 / 245 | 100% | 52.83 | 502 / 502 |
kidney | 100% | 3744.91 | 89 / 89 | 100% | 52.81 | 897 / 901 |
lung | 100% | 7849.14 | 578 / 578 | 99% | 38.88 | 1148 / 1155 |
ovary | 100% | 5007.84 | 180 / 180 | 99% | 33.81 | 427 / 430 |
adrenal gland | 100% | 4781.31 | 258 / 258 | 99% | 41.74 | 228 / 230 |
breast | 100% | 6008.01 | 459 / 459 | 99% | 55.99 | 1103 / 1118 |
bladder | 100% | 7484.43 | 21 / 21 | 98% | 32.90 | 494 / 504 |
intestine | 100% | 6319.49 | 966 / 966 | 98% | 36.41 | 514 / 527 |
stomach | 100% | 4470.18 | 359 / 359 | 97% | 39.94 | 277 / 286 |
uterus | 100% | 6089.77 | 170 / 170 | 97% | 33.57 | 444 / 459 |
skin | 99% | 3210.29 | 1789 / 1809 | 97% | 39.23 | 456 / 472 |
pancreas | 93% | 1862.71 | 306 / 328 | 99% | 43.42 | 177 / 178 |
liver | 97% | 1808.91 | 220 / 226 | 93% | 18.78 | 377 / 406 |
adipose | 100% | 6511.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 7130.29 | 1335 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 30.45 | 45 / 45 |
spleen | 100% | 2737.93 | 240 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 30.38 | 77 / 80 |
muscle | 92% | 1833.80 | 736 / 803 | 0% | 0 | 0 / 0 |
heart | 84% | 1473.69 | 723 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 75% | 3602.94 | 699 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 55% | 6.98 | 16 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0009649 | Biological process | entrainment of circadian clock |
GO_0006469 | Biological process | negative regulation of protein kinase activity |
GO_0007213 | Biological process | G protein-coupled acetylcholine receptor signaling pathway |
GO_0010543 | Biological process | regulation of platelet activation |
GO_0060158 | Biological process | phospholipase C-activating dopamine receptor signaling pathway |
GO_0007596 | Biological process | blood coagulation |
GO_0007603 | Biological process | phototransduction, visible light |
GO_0050821 | Biological process | protein stabilization |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0001508 | Biological process | action potential |
GO_0007215 | Biological process | glutamate receptor signaling pathway |
GO_0060828 | Biological process | regulation of canonical Wnt signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0001750 | Cellular component | photoreceptor outer segment |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0045202 | Cellular component | synapse |
GO_0005737 | Cellular component | cytoplasm |
GO_0005834 | Cellular component | heterotrimeric G-protein complex |
GO_0031965 | Cellular component | nuclear membrane |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0031683 | Molecular function | G-protein beta/gamma-subunit complex binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0001664 | Molecular function | G protein-coupled receptor binding |
GO_0005525 | Molecular function | GTP binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | GNAQ |
Protein name | Guanine nucleotide binding protein Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q) G protein subunit alpha q |
Synonyms | GAQ |
Description | FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Required for platelet activation. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs) . Together with GNA11, required for heart development (By similarity). . |
Accessions | P50148 B1AM21 ENST00000286548.9 ENST00000411677.1 G9FP35 G9FP37 G9FP38 |