GIMAP4 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	37 studies	38% ± 15%	Explore
CD8-positive, alpha-beta T cell	33 studies	40% ± 15%	Explore
CD4-positive, alpha-beta T cell	31 studies	40% ± 14%	Explore
endothelial cell	29 studies	44% ± 16%	Explore
T cell	22 studies	37% ± 13%	Explore
non-classical monocyte	22 studies	36% ± 14%	Explore
regulatory T cell	22 studies	34% ± 12%	Explore
macrophage	19 studies	32% ± 12%	Explore
mature NK T cell	18 studies	40% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	42% ± 16%	Explore
endothelial cell of lymphatic vessel	16 studies	43% ± 15%	Explore
classical monocyte	16 studies	37% ± 13%	Explore
mucosal invariant T cell	15 studies	34% ± 14%	Explore
capillary endothelial cell	15 studies	39% ± 15%	Explore
gamma-delta T cell	15 studies	32% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	38% ± 17%	Explore
monocyte	14 studies	32% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	35% ± 19%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	44% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	37% ± 18%	Explore
endothelial cell of artery	12 studies	51% ± 17%	Explore
vein endothelial cell	12 studies	41% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	38% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	40% ± 17%	Explore
endothelial cell of vascular tree	9 studies	38% ± 11%	Explore
conventional dendritic cell	8 studies	19% ± 5%	Explore
T follicular helper cell	8 studies	39% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	49% ± 18%	Explore
myeloid cell	6 studies	25% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	45% ± 15%	Explore
CD4-positive helper T cell	5 studies	26% ± 6%	Explore
exhausted T cell	5 studies	61% ± 5%	Explore
leukocyte	5 studies	28% ± 5%	Explore
dendritic cell	5 studies	21% ± 2%	Explore
microglial cell	5 studies	27% ± 6%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	41% ± 19%	Explore
glomerular endothelial cell	4 studies	50% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	67% ± 8%	Explore
T-helper 17 cell	4 studies	27% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	41% ± 14%	Explore
lymphocyte	3 studies	26% ± 1%	Explore
innate lymphoid cell	3 studies	36% ± 11%	Explore
T-helper 1 cell	3 studies	36% ± 10%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	54% ± 7%	Explore
double negative thymocyte	3 studies	47% ± 19%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	33% ± 11%	Explore
lung	5 studies	21% ± 3%	Explore
lymph node	4 studies	28% ± 7%	Explore
liver	3 studies	27% ± 12%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	2427.36	652 / 653	99%	47.96	601 / 605
breast	100%	3392.74	459 / 459	99%	51.66	1102 / 1118
lung	100%	4313.49	578 / 578	93%	40.28	1074 / 1155
kidney	100%	1469.37	89 / 89	92%	92.50	832 / 901
adrenal gland	97%	1112.74	249 / 258	90%	32.20	208 / 230
prostate	95%	1129.46	233 / 245	89%	22.23	447 / 502
uterus	99%	2115.34	169 / 170	79%	24.84	364 / 459
intestine	99%	1702.22	952 / 966	78%	22.01	412 / 527
bladder	100%	1385.24	21 / 21	77%	23.16	386 / 504
stomach	88%	905.55	315 / 359	82%	27.60	235 / 286
esophagus	89%	1167.47	1279 / 1445	77%	19.41	141 / 183
brain	63%	560.14	1663 / 2642	98%	41.71	692 / 705
skin	55%	485.87	997 / 1809	83%	46.47	393 / 472
liver	48%	385.21	109 / 226	88%	24.60	356 / 406
ovary	51%	466.28	91 / 180	80%	21.45	345 / 430
pancreas	35%	214.72	114 / 328	94%	40.08	168 / 178
adipose	100%	3855.84	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	163.19	29 / 29
spleen	100%	6608.26	241 / 241	0%	0	0 / 0
heart	98%	1396.98	840 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	41.14	40 / 45
peripheral blood	86%	4923.80	800 / 929	0%	0	0 / 0
blood vessel	82%	1123.64	1100 / 1335	0%	0	0 / 0
muscle	81%	631.96	653 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	34%	9.12	27 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1