FKBP3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	17 studies	26% ± 9%	Explore
fibroblast	14 studies	26% ± 10%	Explore
smooth muscle cell	13 studies	24% ± 7%	Explore
epithelial cell	10 studies	37% ± 21%	Explore
plasmacytoid dendritic cell	10 studies	26% ± 9%	Explore
CD4-positive, alpha-beta T cell	9 studies	21% ± 4%	Explore
connective tissue cell	9 studies	30% ± 10%	Explore
natural killer cell	9 studies	20% ± 6%	Explore
pericyte	9 studies	23% ± 7%	Explore
regulatory T cell	9 studies	18% ± 2%	Explore
neuron	8 studies	39% ± 14%	Explore
glutamatergic neuron	8 studies	38% ± 22%	Explore
basal cell	8 studies	32% ± 15%	Explore
CD8-positive, alpha-beta T cell	8 studies	20% ± 2%	Explore
B cell	7 studies	23% ± 8%	Explore
conventional dendritic cell	7 studies	29% ± 18%	Explore
progenitor cell	7 studies	28% ± 5%	Explore
macrophage	7 studies	23% ± 10%	Explore
T cell	7 studies	21% ± 10%	Explore
endothelial cell of lymphatic vessel	7 studies	27% ± 7%	Explore
myofibroblast cell	6 studies	26% ± 5%	Explore
astrocyte	6 studies	24% ± 8%	Explore
hematopoietic precursor cell	5 studies	33% ± 22%	Explore
kidney loop of Henle epithelial cell	5 studies	22% ± 6%	Explore
epithelial cell of proximal tubule	5 studies	21% ± 6%	Explore
abnormal cell	5 studies	29% ± 13%	Explore
mesothelial cell	5 studies	29% ± 15%	Explore
erythroblast	5 studies	31% ± 16%	Explore
ciliated cell	5 studies	34% ± 12%	Explore
GABAergic neuron	5 studies	37% ± 16%	Explore
oligodendrocyte precursor cell	5 studies	31% ± 5%	Explore
interneuron	5 studies	33% ± 16%	Explore
oligodendrocyte	5 studies	25% ± 2%	Explore
plasmablast	4 studies	44% ± 18%	Explore
non-classical monocyte	4 studies	24% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	18% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	19% ± 4%	Explore
enterocyte	4 studies	19% ± 1%	Explore
enteroendocrine cell	4 studies	34% ± 15%	Explore
retinal ganglion cell	4 studies	67% ± 25%	Explore
pro-B cell	4 studies	26% ± 4%	Explore
amacrine cell	4 studies	35% ± 17%	Explore
retina horizontal cell	4 studies	35% ± 17%	Explore
hematopoietic stem cell	4 studies	25% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 2%	Explore
pancreatic A cell	3 studies	49% ± 6%	Explore
type B pancreatic cell	3 studies	42% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	17% ± 1%	Explore
classical monocyte	3 studies	29% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	19% ± 1%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	36% ± 13%	Explore
endothelial cell of artery	3 studies	20% ± 5%	Explore
neural crest cell	3 studies	37% ± 8%	Explore
retinal bipolar neuron	3 studies	42% ± 19%	Explore
placental villous trophoblast	3 studies	48% ± 24%	Explore
club cell	3 studies	26% ± 5%	Explore
neuroendocrine cell	3 studies	35% ± 10%	Explore
precursor B cell	3 studies	28% ± 10%	Explore
type I pneumocyte	3 studies	28% ± 9%	Explore
type II pneumocyte	3 studies	27% ± 11%	Explore
retinal cone cell	3 studies	52% ± 14%	Explore
retinal rod cell	3 studies	36% ± 13%	Explore
myeloid cell	3 studies	27% ± 11%	Explore
rod bipolar cell	3 studies	38% ± 11%	Explore
germinal center B cell	3 studies	20% ± 2%	Explore
dendritic cell	3 studies	45% ± 10%	Explore
pancreatic ductal cell	3 studies	43% ± 19%	Explore
granulocyte monocyte progenitor cell	3 studies	34% ± 20%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	42% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	23% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	27% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	12 studies	28% ± 14%	Explore
peripheral blood	7 studies	20% ± 8%	Explore
lung	7 studies	29% ± 12%	Explore
intestine	6 studies	25% ± 11%	Explore
eye	6 studies	30% ± 13%	Explore
kidney	4 studies	22% ± 6%	Explore
liver	4 studies	30% ± 19%	Explore
pancreas	3 studies	44% ± 7%	Explore
bone marrow	3 studies	19% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	1929.50	245 / 245	100%	65.91	502 / 502
brain	100%	3222.19	2641 / 2642	100%	55.89	705 / 705
esophagus	100%	1615.81	1444 / 1445	100%	41.72	183 / 183
bladder	100%	1507.71	21 / 21	100%	49.27	503 / 504
ovary	100%	1428.89	180 / 180	100%	44.40	429 / 430
uterus	100%	1432.03	170 / 170	100%	62.52	457 / 459
kidney	100%	1932.21	89 / 89	100%	34.07	897 / 901
thymus	100%	1669.79	653 / 653	100%	47.08	602 / 605
breast	100%	1499.43	459 / 459	99%	61.10	1111 / 1118
stomach	100%	1247.01	359 / 359	99%	40.38	284 / 286
skin	100%	1849.39	1804 / 1809	99%	43.02	468 / 472
intestine	100%	1702.38	966 / 966	99%	43.09	521 / 527
liver	100%	1215.84	226 / 226	99%	34.44	401 / 406
lung	99%	1215.62	570 / 578	100%	48.74	1155 / 1155
adrenal gland	100%	1878.95	258 / 258	98%	48.11	226 / 230
pancreas	95%	756.25	313 / 328	99%	39.28	177 / 178
lymph node	0%	0	0 / 0	100%	63.09	29 / 29
muscle	100%	7187.91	803 / 803	0%	0	0 / 0
spleen	100%	1637.28	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	49.99	45 / 45
ureter	0%	0	0 / 0	100%	27.50	1 / 1
adipose	100%	1431.73	1202 / 1204	0%	0	0 / 0
blood vessel	99%	1381.77	1326 / 1335	0%	0	0 / 0
heart	96%	2472.00	829 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	34.04	77 / 80
peripheral blood	43%	965.45	402 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0005634	Cellular component	nucleus
GO_0005528	Molecular function	FK506 binding
GO_0038023	Molecular function	signaling receptor activity
GO_0005515	Molecular function	protein binding
GO_0003755	Molecular function	peptidyl-prolyl cis-trans isomerase activity
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	FKBP3
Protein name	FKBP prolyl isomerase 3 Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)
Synonyms	FKBP25
Description	FUNCTION: FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
Accessions	ENST00000216330.7 ENST00000557324.5 Q00688 ENST00000396062.4 G3V5F2

FKBP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review