Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 31 studies | 45% ± 18% | |
astrocyte | 19 studies | 48% ± 19% | |
fibroblast | 16 studies | 40% ± 15% | |
pericyte | 15 studies | 41% ± 17% | |
microglial cell | 15 studies | 48% ± 17% | |
oligodendrocyte precursor cell | 14 studies | 45% ± 18% | |
glutamatergic neuron | 13 studies | 67% ± 21% | |
macrophage | 13 studies | 42% ± 18% | |
oligodendrocyte | 13 studies | 35% ± 17% | |
smooth muscle cell | 12 studies | 42% ± 15% | |
GABAergic neuron | 11 studies | 68% ± 21% | |
endothelial cell of lymphatic vessel | 10 studies | 36% ± 15% | |
epithelial cell | 9 studies | 39% ± 19% | |
adipocyte | 9 studies | 54% ± 14% | |
endothelial cell of artery | 9 studies | 29% ± 16% | |
mast cell | 9 studies | 33% ± 11% | |
dendritic cell | 8 studies | 35% ± 13% | |
basal cell | 8 studies | 40% ± 25% | |
neuron | 7 studies | 53% ± 24% | |
interneuron | 7 studies | 70% ± 25% | |
myeloid cell | 7 studies | 38% ± 14% | |
mesothelial cell | 7 studies | 39% ± 13% | |
ciliated cell | 7 studies | 31% ± 15% | |
B cell | 6 studies | 33% ± 11% | |
amacrine cell | 6 studies | 48% ± 24% | |
retina horizontal cell | 6 studies | 70% ± 28% | |
plasma cell | 5 studies | 44% ± 12% | |
cardiac muscle cell | 5 studies | 64% ± 14% | |
T cell | 5 studies | 29% ± 10% | |
monocyte | 5 studies | 46% ± 7% | |
type I pneumocyte | 5 studies | 50% ± 8% | |
type II pneumocyte | 5 studies | 46% ± 7% | |
granule cell | 4 studies | 79% ± 7% | |
vein endothelial cell | 4 studies | 49% ± 16% | |
lymphocyte | 4 studies | 28% ± 11% | |
Mueller cell | 4 studies | 65% ± 10% | |
retinal cone cell | 4 studies | 48% ± 13% | |
retinal ganglion cell | 4 studies | 79% ± 14% | |
retinal rod cell | 4 studies | 40% ± 6% | |
endothelial cell of vascular tree | 4 studies | 47% ± 18% | |
respiratory goblet cell | 4 studies | 41% ± 20% | |
club cell | 4 studies | 49% ± 13% | |
natural killer cell | 4 studies | 23% ± 5% | |
classical monocyte | 3 studies | 17% ± 1% | |
plasmablast | 3 studies | 22% ± 7% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 45% ± 8% | |
GABAergic interneuron | 3 studies | 78% ± 2% | |
glial cell | 3 studies | 34% ± 15% | |
progenitor cell | 3 studies | 45% ± 6% | |
CD4-positive, alpha-beta T cell | 3 studies | 24% ± 2% | |
GABAergic amacrine cell | 3 studies | 72% ± 10% | |
OFF-bipolar cell | 3 studies | 44% ± 6% | |
ON-bipolar cell | 3 studies | 48% ± 3% | |
glycinergic amacrine cell | 3 studies | 62% ± 7% | |
chondrocyte | 3 studies | 34% ± 14% | |
melanocyte | 3 studies | 50% ± 28% | |
hepatocyte | 3 studies | 69% ± 19% | |
retinal pigment epithelial cell | 3 studies | 49% ± 27% | |
neural progenitor cell | 3 studies | 45% ± 20% | |
connective tissue cell | 3 studies | 37% ± 8% | |
ependymal cell | 3 studies | 60% ± 14% | |
myofibroblast cell | 3 studies | 45% ± 16% | |
alveolar macrophage | 3 studies | 53% ± 9% | |
capillary endothelial cell | 3 studies | 45% ± 6% | |
muscle cell | 3 studies | 49% ± 30% | |
goblet cell | 3 studies | 46% ± 35% | |
renal principal cell | 3 studies | 55% ± 27% | |
mucus secreting cell | 3 studies | 40% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5136.77 | 1445 / 1445 | 99% | 24.48 | 182 / 183 |
skin | 100% | 4461.79 | 1808 / 1809 | 99% | 27.59 | 469 / 472 |
brain | 100% | 4102.14 | 2641 / 2642 | 99% | 21.48 | 696 / 705 |
breast | 100% | 3850.36 | 459 / 459 | 99% | 20.77 | 1103 / 1118 |
ovary | 100% | 3141.92 | 180 / 180 | 98% | 17.13 | 420 / 430 |
prostate | 100% | 4013.62 | 245 / 245 | 97% | 13.92 | 489 / 502 |
thymus | 100% | 3800.30 | 653 / 653 | 97% | 16.47 | 587 / 605 |
stomach | 99% | 2782.55 | 357 / 359 | 98% | 13.56 | 279 / 286 |
adrenal gland | 100% | 4089.79 | 258 / 258 | 97% | 16.98 | 222 / 230 |
lung | 100% | 3291.65 | 577 / 578 | 97% | 14.83 | 1115 / 1155 |
kidney | 100% | 2396.65 | 89 / 89 | 96% | 16.71 | 865 / 901 |
intestine | 100% | 4148.63 | 966 / 966 | 95% | 11.87 | 503 / 527 |
uterus | 100% | 4209.63 | 170 / 170 | 95% | 14.91 | 436 / 459 |
bladder | 100% | 6149.90 | 21 / 21 | 92% | 11.25 | 463 / 504 |
pancreas | 90% | 1158.08 | 295 / 328 | 96% | 13.30 | 171 / 178 |
liver | 98% | 1362.48 | 222 / 226 | 67% | 5.58 | 271 / 406 |
adipose | 100% | 4175.32 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5841.40 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1911.06 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 17.83 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.72 | 1 / 1 |
muscle | 99% | 2243.95 | 798 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 3178.21 | 851 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 17.36 | 79 / 80 |
lymph node | 0% | 0 | 0 / 0 | 90% | 9.10 | 26 / 29 |
peripheral blood | 19% | 213.00 | 181 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007274 | Biological process | neuromuscular synaptic transmission |
GO_0048790 | Biological process | maintenance of presynaptic active zone structure |
GO_0042147 | Biological process | retrograde transport, endosome to Golgi |
GO_0051092 | Biological process | positive regulation of NF-kappaB transcription factor activity |
GO_0048167 | Biological process | regulation of synaptic plasticity |
GO_0007252 | Biological process | I-kappaB phosphorylation |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0015031 | Biological process | protein transport |
GO_0005813 | Cellular component | centrosome |
GO_0042734 | Cellular component | presynaptic membrane |
GO_0000139 | Cellular component | Golgi membrane |
GO_0048788 | Cellular component | cytoskeleton of presynaptic active zone |
GO_0045202 | Cellular component | synapse |
GO_0005737 | Cellular component | cytoplasm |
GO_0008385 | Cellular component | IkappaB kinase complex |
GO_0036064 | Cellular component | ciliary basal body |
GO_0045296 | Molecular function | cadherin binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0030165 | Molecular function | PDZ domain binding |
GO_0098882 | Molecular function | structural constituent of presynaptic active zone |
GO_0005515 | Molecular function | protein binding |
Gene name | ERC1 |
Protein name | ELKS/RAB6-interacting/CAST family member 1 ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2) |
Synonyms | KIAA1081 ELKS RAB6IP2 |
Description | FUNCTION: Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. . |
Accessions | Q8IUD2 K7EPD6 X6RM00 ENST00000688324.1 ENST00000588412.5 ENST00000545318.3 A0A8I5KT07 A0A8I5KS52 X6RLX0 ENST00000347735.10 [Q8IUD2-4] ENST00000440394.7 [Q8IUD2-2] ENST00000360905.9 [Q8IUD2-1] G8JLD3 ENST00000543086.7 [Q8IUD2-3] ENST00000589028.6 [Q8IUD2-1] ENST00000546231.6 ENST00000689995.1 ENST00000589132.1 ENST00000691177.1 ENST00000592048.5 ENST00000542302.6 K7EP25 ENST00000355446.9 ENST00000611180.5 A0A8I5QKW1 ENST00000539802.2 K7EIZ7 A0A8J9C065 ENST00000397203.7 [Q8IUD2-1] K7EPP6 K7EKH8 ENST00000545948.5 [Q8IUD2-5] |