Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 29 studies | 36% ± 17% | |
fibroblast | 26 studies | 37% ± 19% | |
non-classical monocyte | 23 studies | 46% ± 18% | |
smooth muscle cell | 22 studies | 33% ± 12% | |
macrophage | 20 studies | 35% ± 19% | |
classical monocyte | 18 studies | 29% ± 10% | |
astrocyte | 17 studies | 43% ± 17% | |
plasmacytoid dendritic cell | 16 studies | 37% ± 11% | |
pericyte | 16 studies | 33% ± 17% | |
microglial cell | 15 studies | 50% ± 15% | |
monocyte | 14 studies | 35% ± 20% | |
oligodendrocyte | 13 studies | 38% ± 14% | |
oligodendrocyte precursor cell | 13 studies | 39% ± 17% | |
epithelial cell | 13 studies | 42% ± 22% | |
type I pneumocyte | 12 studies | 54% ± 24% | |
B cell | 12 studies | 25% ± 10% | |
basal cell | 11 studies | 36% ± 20% | |
glutamatergic neuron | 11 studies | 47% ± 22% | |
myofibroblast cell | 11 studies | 29% ± 15% | |
myeloid cell | 11 studies | 39% ± 17% | |
ciliated cell | 11 studies | 32% ± 15% | |
mast cell | 11 studies | 33% ± 13% | |
mesothelial cell | 10 studies | 48% ± 18% | |
endothelial cell of lymphatic vessel | 9 studies | 40% ± 14% | |
GABAergic neuron | 9 studies | 47% ± 22% | |
adipocyte | 9 studies | 49% ± 14% | |
dendritic cell | 9 studies | 47% ± 18% | |
type II pneumocyte | 8 studies | 47% ± 21% | |
club cell | 8 studies | 40% ± 19% | |
connective tissue cell | 8 studies | 30% ± 18% | |
neuron | 7 studies | 39% ± 26% | |
amacrine cell | 7 studies | 42% ± 16% | |
interneuron | 7 studies | 51% ± 21% | |
retinal ganglion cell | 7 studies | 55% ± 19% | |
hematopoietic stem cell | 7 studies | 29% ± 10% | |
conventional dendritic cell | 6 studies | 29% ± 12% | |
abnormal cell | 6 studies | 36% ± 18% | |
retina horizontal cell | 6 studies | 36% ± 15% | |
retinal cone cell | 6 studies | 36% ± 14% | |
cardiac muscle cell | 6 studies | 61% ± 24% | |
Mueller cell | 6 studies | 36% ± 17% | |
T cell | 6 studies | 33% ± 14% | |
hematopoietic precursor cell | 5 studies | 39% ± 22% | |
progenitor cell | 5 studies | 35% ± 14% | |
precursor B cell | 5 studies | 33% ± 6% | |
pro-B cell | 5 studies | 29% ± 4% | |
vein endothelial cell | 5 studies | 26% ± 11% | |
lymphocyte | 5 studies | 32% ± 9% | |
respiratory goblet cell | 5 studies | 50% ± 23% | |
endothelial cell of vascular tree | 5 studies | 29% ± 13% | |
goblet cell | 5 studies | 34% ± 24% | |
natural killer cell | 5 studies | 25% ± 6% | |
secretory cell | 4 studies | 23% ± 4% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 21% ± 4% | |
granule cell | 4 studies | 57% ± 17% | |
plasma cell | 4 studies | 40% ± 10% | |
capillary endothelial cell | 4 studies | 29% ± 11% | |
retinal bipolar neuron | 4 studies | 30% ± 13% | |
retinal pigment epithelial cell | 4 studies | 44% ± 23% | |
CD4-positive, alpha-beta T cell | 4 studies | 22% ± 5% | |
mononuclear phagocyte | 4 studies | 38% ± 16% | |
ON-bipolar cell | 4 studies | 38% ± 15% | |
retinal rod cell | 4 studies | 47% ± 10% | |
muscle cell | 4 studies | 43% ± 24% | |
epithelial cell of proximal tubule | 4 studies | 44% ± 28% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 24% ± 3% | |
plasmablast | 3 studies | 33% ± 13% | |
glomerular endothelial cell | 3 studies | 17% ± 1% | |
podocyte | 3 studies | 50% ± 23% | |
renal beta-intercalated cell | 3 studies | 36% ± 17% | |
GABAergic interneuron | 3 studies | 45% ± 12% | |
glial cell | 3 studies | 37% ± 8% | |
platelet | 3 studies | 22% ± 4% | |
CD8-positive, alpha-beta T cell | 3 studies | 22% ± 6% | |
GABAergic amacrine cell | 3 studies | 50% ± 5% | |
OFF-bipolar cell | 3 studies | 46% ± 14% | |
glycinergic amacrine cell | 3 studies | 52% ± 10% | |
rod bipolar cell | 3 studies | 35% ± 11% | |
germinal center B cell | 3 studies | 27% ± 10% | |
endothelial cell of artery | 3 studies | 21% ± 5% | |
cholangiocyte | 3 studies | 66% ± 16% | |
hepatocyte | 3 studies | 74% ± 20% | |
neural progenitor cell | 3 studies | 43% ± 17% | |
neutrophil | 3 studies | 39% ± 14% | |
enteroendocrine cell | 3 studies | 24% ± 5% | |
leukocyte | 3 studies | 35% ± 15% | |
alveolar macrophage | 3 studies | 58% ± 9% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 20% ± 6% | |
kidney loop of Henle epithelial cell | 3 studies | 30% ± 12% | |
mural cell | 3 studies | 45% ± 12% | |
mucus secreting cell | 3 studies | 58% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 17 studies | 44% ± 19% | |
lung | 12 studies | 32% ± 17% | |
eye | 8 studies | 39% ± 20% | |
peripheral blood | 7 studies | 23% ± 9% | |
heart | 5 studies | 49% ± 14% | |
kidney | 4 studies | 40% ± 16% | |
bone marrow | 4 studies | 27% ± 17% | |
liver | 4 studies | 38% ± 23% | |
intestine | 4 studies | 20% ± 6% | |
adipose | 4 studies | 38% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 7404.05 | 1445 / 1445 | 100% | 47.06 | 183 / 183 |
intestine | 100% | 8500.31 | 966 / 966 | 100% | 33.71 | 527 / 527 |
kidney | 100% | 7931.55 | 89 / 89 | 100% | 37.78 | 901 / 901 |
pancreas | 100% | 3682.70 | 328 / 328 | 100% | 26.91 | 178 / 178 |
prostate | 100% | 6838.78 | 245 / 245 | 100% | 32.25 | 502 / 502 |
stomach | 100% | 6098.57 | 359 / 359 | 100% | 34.29 | 286 / 286 |
thymus | 100% | 8265.47 | 653 / 653 | 100% | 35.53 | 605 / 605 |
brain | 100% | 6488.26 | 2640 / 2642 | 100% | 32.47 | 705 / 705 |
lung | 100% | 7996.26 | 578 / 578 | 100% | 31.11 | 1154 / 1155 |
ovary | 100% | 8583.32 | 180 / 180 | 100% | 24.00 | 429 / 430 |
skin | 100% | 4678.30 | 1807 / 1809 | 100% | 22.62 | 471 / 472 |
bladder | 100% | 8655.14 | 21 / 21 | 99% | 23.81 | 500 / 504 |
uterus | 100% | 14977.32 | 170 / 170 | 99% | 22.03 | 455 / 459 |
breast | 100% | 4153.40 | 459 / 459 | 99% | 22.19 | 1108 / 1118 |
adrenal gland | 100% | 3859.34 | 258 / 258 | 96% | 17.24 | 220 / 230 |
liver | 100% | 2570.25 | 225 / 226 | 91% | 11.87 | 370 / 406 |
adipose | 100% | 5614.05 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 9120.26 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 20.36 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 22.60 | 29 / 29 |
muscle | 100% | 6860.13 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3503.56 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 24.61 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.44 | 1 / 1 |
heart | 98% | 7312.01 | 847 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 3993.01 | 894 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0050775 | Biological process | positive regulation of dendrite morphogenesis |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006891 | Biological process | intra-Golgi vesicle-mediated transport |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005634 | Cellular component | nucleus |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
Gene name | CUX1 |
Protein name | Homeobox protein cut-like CUX1/RET fusion Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP/Cux p200) (Homeobox protein cux-1) [Cleaved into: CDP/Cux p110] Protein CASP Cut like homeobox 1 Mutant CUX1 |
Synonyms | fusion CUTL1 RET |
Description | FUNCTION: Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III. Also involved in the control of synaptogenesis. In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator. .; FUNCTION: [CDP/Cux p110]: Plays a role in cell cycle progression, in particular at the G1/S transition. As cells progress into S phase, a fraction of CUX1 molecules is proteolytically processed into N-terminally truncated proteins of 110 kDa. While CUX1 only transiently binds to DNA and carries the CCAAT-displacement activity, CDP/Cux p110 makes a stable interaction with DNA and stimulates expression of genes such as POLA1. . FUNCTION: May be involved in intra-Golgi retrograde transport. . |
Accessions | ENST00000393824.7 [Q13948-9] A0A2R8Y8D0 ENST00000292538.9 [Q13948-1] ENST00000549414.6 [P39880-2] T1SG88 ENST00000465461.7 Q13948 A0A7D4XDC1 ENST00000292535.12 [P39880-1] ENST00000646649.1 A0A2R8Y852 A0A2R8YDI1 ENST00000622516.6 [Q13948-1] ENST00000645010.1 P39880 ENST00000546411.7 [P39880-1] ENST00000437600.9 [Q13948-2] ENST00000550008.6 [P39880-5] ENST00000360264.7 [P39880-3] ENST00000547394.6 [Q13948-10] ENST00000556210.1 [P39880-6] ENST00000425244.6 [P39880-9] |