Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 29 studies | 36% ± 17% | |
| fibroblast | 26 studies | 37% ± 19% | |
| non-classical monocyte | 23 studies | 46% ± 18% | |
| smooth muscle cell | 22 studies | 33% ± 12% | |
| macrophage | 20 studies | 35% ± 19% | |
| classical monocyte | 18 studies | 29% ± 10% | |
| astrocyte | 17 studies | 43% ± 17% | |
| plasmacytoid dendritic cell | 16 studies | 37% ± 11% | |
| pericyte | 16 studies | 33% ± 17% | |
| microglial cell | 15 studies | 50% ± 15% | |
| monocyte | 14 studies | 35% ± 20% | |
| oligodendrocyte | 13 studies | 38% ± 14% | |
| oligodendrocyte precursor cell | 13 studies | 39% ± 17% | |
| epithelial cell | 13 studies | 42% ± 22% | |
| type I pneumocyte | 12 studies | 54% ± 24% | |
| B cell | 12 studies | 25% ± 10% | |
| basal cell | 11 studies | 36% ± 20% | |
| glutamatergic neuron | 11 studies | 47% ± 22% | |
| myofibroblast cell | 11 studies | 29% ± 15% | |
| myeloid cell | 11 studies | 39% ± 17% | |
| ciliated cell | 11 studies | 32% ± 15% | |
| mast cell | 11 studies | 33% ± 13% | |
| mesothelial cell | 10 studies | 48% ± 18% | |
| endothelial cell of lymphatic vessel | 9 studies | 40% ± 14% | |
| GABAergic neuron | 9 studies | 47% ± 22% | |
| adipocyte | 9 studies | 49% ± 14% | |
| dendritic cell | 9 studies | 47% ± 18% | |
| type II pneumocyte | 8 studies | 47% ± 21% | |
| club cell | 8 studies | 40% ± 19% | |
| connective tissue cell | 8 studies | 30% ± 18% | |
| neuron | 7 studies | 39% ± 26% | |
| amacrine cell | 7 studies | 42% ± 16% | |
| interneuron | 7 studies | 51% ± 21% | |
| retinal ganglion cell | 7 studies | 55% ± 19% | |
| hematopoietic stem cell | 7 studies | 29% ± 10% | |
| conventional dendritic cell | 6 studies | 29% ± 12% | |
| abnormal cell | 6 studies | 36% ± 18% | |
| retina horizontal cell | 6 studies | 36% ± 15% | |
| retinal cone cell | 6 studies | 36% ± 14% | |
| cardiac muscle cell | 6 studies | 61% ± 24% | |
| Mueller cell | 6 studies | 36% ± 17% | |
| T cell | 6 studies | 33% ± 14% | |
| hematopoietic precursor cell | 5 studies | 39% ± 22% | |
| progenitor cell | 5 studies | 35% ± 14% | |
| precursor B cell | 5 studies | 33% ± 6% | |
| pro-B cell | 5 studies | 29% ± 4% | |
| vein endothelial cell | 5 studies | 26% ± 11% | |
| lymphocyte | 5 studies | 32% ± 9% | |
| respiratory goblet cell | 5 studies | 50% ± 23% | |
| endothelial cell of vascular tree | 5 studies | 29% ± 13% | |
| goblet cell | 5 studies | 34% ± 24% | |
| natural killer cell | 5 studies | 25% ± 6% | |
| secretory cell | 4 studies | 23% ± 4% | |
| CD16-negative, CD56-bright natural killer cell, human | 4 studies | 21% ± 4% | |
| granule cell | 4 studies | 57% ± 17% | |
| plasma cell | 4 studies | 40% ± 10% | |
| capillary endothelial cell | 4 studies | 29% ± 11% | |
| retinal bipolar neuron | 4 studies | 30% ± 13% | |
| retinal pigment epithelial cell | 4 studies | 44% ± 23% | |
| CD4-positive, alpha-beta T cell | 4 studies | 22% ± 5% | |
| mononuclear phagocyte | 4 studies | 38% ± 16% | |
| ON-bipolar cell | 4 studies | 38% ± 15% | |
| retinal rod cell | 4 studies | 47% ± 10% | |
| muscle cell | 4 studies | 43% ± 24% | |
| epithelial cell of proximal tubule | 4 studies | 44% ± 28% | |
| effector memory CD8-positive, alpha-beta T cell | 3 studies | 24% ± 3% | |
| plasmablast | 3 studies | 33% ± 13% | |
| glomerular endothelial cell | 3 studies | 17% ± 1% | |
| podocyte | 3 studies | 50% ± 23% | |
| renal beta-intercalated cell | 3 studies | 36% ± 17% | |
| GABAergic interneuron | 3 studies | 45% ± 12% | |
| glial cell | 3 studies | 37% ± 8% | |
| platelet | 3 studies | 22% ± 4% | |
| CD8-positive, alpha-beta T cell | 3 studies | 22% ± 6% | |
| GABAergic amacrine cell | 3 studies | 50% ± 5% | |
| OFF-bipolar cell | 3 studies | 46% ± 14% | |
| glycinergic amacrine cell | 3 studies | 52% ± 10% | |
| rod bipolar cell | 3 studies | 35% ± 11% | |
| germinal center B cell | 3 studies | 27% ± 10% | |
| endothelial cell of artery | 3 studies | 21% ± 5% | |
| cholangiocyte | 3 studies | 66% ± 16% | |
| hepatocyte | 3 studies | 74% ± 20% | |
| neural progenitor cell | 3 studies | 43% ± 17% | |
| neutrophil | 3 studies | 39% ± 14% | |
| enteroendocrine cell | 3 studies | 24% ± 5% | |
| leukocyte | 3 studies | 35% ± 15% | |
| alveolar macrophage | 3 studies | 58% ± 9% | |
| CD16-positive, CD56-dim natural killer cell, human | 3 studies | 20% ± 6% | |
| kidney loop of Henle epithelial cell | 3 studies | 30% ± 12% | |
| mural cell | 3 studies | 45% ± 12% | |
| mucus secreting cell | 3 studies | 58% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 17 studies | 44% ± 19% | |
| lung | 12 studies | 32% ± 17% | |
| eye | 8 studies | 39% ± 20% | |
| peripheral blood | 7 studies | 23% ± 9% | |
| heart | 5 studies | 49% ± 14% | |
| kidney | 4 studies | 40% ± 16% | |
| bone marrow | 4 studies | 27% ± 17% | |
| liver | 4 studies | 38% ± 23% | |
| intestine | 4 studies | 20% ± 6% | |
| adipose | 4 studies | 38% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 7404.05 | 1445 / 1445 | 100% | 47.06 | 183 / 183 |
| intestine | 100% | 8500.31 | 966 / 966 | 100% | 33.71 | 527 / 527 |
| kidney | 100% | 7931.55 | 89 / 89 | 100% | 37.78 | 901 / 901 |
| pancreas | 100% | 3682.70 | 328 / 328 | 100% | 26.91 | 178 / 178 |
| prostate | 100% | 6838.78 | 245 / 245 | 100% | 32.25 | 502 / 502 |
| stomach | 100% | 6098.57 | 359 / 359 | 100% | 34.29 | 286 / 286 |
| thymus | 100% | 8265.47 | 653 / 653 | 100% | 35.53 | 605 / 605 |
| brain | 100% | 6488.26 | 2640 / 2642 | 100% | 32.47 | 705 / 705 |
| lung | 100% | 7996.26 | 578 / 578 | 100% | 31.11 | 1154 / 1155 |
| ovary | 100% | 8583.32 | 180 / 180 | 100% | 24.00 | 429 / 430 |
| skin | 100% | 4678.30 | 1807 / 1809 | 100% | 22.62 | 471 / 472 |
| bladder | 100% | 8655.14 | 21 / 21 | 99% | 23.81 | 500 / 504 |
| uterus | 100% | 14977.32 | 170 / 170 | 99% | 22.03 | 455 / 459 |
| breast | 100% | 4153.40 | 459 / 459 | 99% | 22.19 | 1108 / 1118 |
| adrenal gland | 100% | 3859.34 | 258 / 258 | 96% | 17.24 | 220 / 230 |
| liver | 100% | 2570.25 | 225 / 226 | 91% | 11.87 | 370 / 406 |
| adipose | 100% | 5614.05 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 9120.26 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 20.36 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 22.60 | 29 / 29 |
| muscle | 100% | 6860.13 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3503.56 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 24.61 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.44 | 1 / 1 |
| heart | 98% | 7312.01 | 847 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 96% | 3993.01 | 894 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0050775 | Biological process | positive regulation of dendrite morphogenesis |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006891 | Biological process | intra-Golgi vesicle-mediated transport |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0000785 | Cellular component | chromatin |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005634 | Cellular component | nucleus |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| Gene name | CUX1 |
| Protein name | Homeobox protein cut-like CUX1/RET fusion Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP/Cux p200) (Homeobox protein cux-1) [Cleaved into: CDP/Cux p110] Protein CASP Cut like homeobox 1 Mutant CUX1 |
| Synonyms | fusion CUTL1 RET |
| Description | FUNCTION: Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III. Also involved in the control of synaptogenesis. In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator. .; FUNCTION: [CDP/Cux p110]: Plays a role in cell cycle progression, in particular at the G1/S transition. As cells progress into S phase, a fraction of CUX1 molecules is proteolytically processed into N-terminally truncated proteins of 110 kDa. While CUX1 only transiently binds to DNA and carries the CCAAT-displacement activity, CDP/Cux p110 makes a stable interaction with DNA and stimulates expression of genes such as POLA1. . FUNCTION: May be involved in intra-Golgi retrograde transport. . |
| Accessions | ENST00000393824.7 [Q13948-9] A0A2R8Y8D0 ENST00000292538.9 [Q13948-1] ENST00000549414.6 [P39880-2] T1SG88 ENST00000465461.7 Q13948 A0A7D4XDC1 ENST00000292535.12 [P39880-1] ENST00000646649.1 A0A2R8Y852 A0A2R8YDI1 ENST00000622516.6 [Q13948-1] ENST00000645010.1 P39880 ENST00000546411.7 [P39880-1] ENST00000437600.9 [Q13948-2] ENST00000550008.6 [P39880-5] ENST00000360264.7 [P39880-3] ENST00000547394.6 [Q13948-10] ENST00000556210.1 [P39880-6] ENST00000425244.6 [P39880-9] |