CMC1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	43 studies	54% ± 23%	Explore
CD8-positive, alpha-beta T cell	28 studies	30% ± 12%	Explore
mature NK T cell	20 studies	39% ± 17%	Explore
CD16-negative, CD56-bright natural killer cell, human	17 studies	62% ± 22%	Explore
CD16-positive, CD56-dim natural killer cell, human	17 studies	48% ± 17%	Explore
endothelial cell	13 studies	24% ± 6%	Explore
gamma-delta T cell	12 studies	37% ± 17%	Explore
T cell	11 studies	24% ± 9%	Explore
mucosal invariant T cell	10 studies	26% ± 5%	Explore
fibroblast	9 studies	21% ± 6%	Explore
macrophage	9 studies	26% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	32% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	40% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	34% ± 8%	Explore
oligodendrocyte	7 studies	24% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	35% ± 15%	Explore
microglial cell	6 studies	22% ± 6%	Explore
epithelial cell	6 studies	39% ± 14%	Explore
ciliated cell	6 studies	29% ± 10%	Explore
innate lymphoid cell	6 studies	42% ± 21%	Explore
astrocyte	6 studies	28% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	32% ± 15%	Explore
lymphocyte	5 studies	30% ± 12%	Explore
CD4-positive, alpha-beta T cell	5 studies	17% ± 1%	Explore
endothelial cell of lymphatic vessel	5 studies	20% ± 4%	Explore
exhausted T cell	4 studies	42% ± 8%	Explore
leukocyte	4 studies	26% ± 12%	Explore
conventional dendritic cell	4 studies	28% ± 10%	Explore
kidney loop of Henle epithelial cell	4 studies	19% ± 4%	Explore
cardiac muscle cell	4 studies	18% ± 2%	Explore
regulatory T cell	4 studies	17% ± 2%	Explore
GABAergic neuron	4 studies	48% ± 17%	Explore
oligodendrocyte precursor cell	4 studies	29% ± 7%	Explore
goblet cell	4 studies	21% ± 5%	Explore
hematopoietic precursor cell	3 studies	20% ± 3%	Explore
non-classical monocyte	3 studies	20% ± 3%	Explore
retinal ganglion cell	3 studies	29% ± 11%	Explore
smooth muscle cell	3 studies	16% ± 1%	Explore
retinal cone cell	3 studies	27% ± 6%	Explore
myeloid cell	3 studies	24% ± 7%	Explore
glutamatergic neuron	3 studies	64% ± 3%	Explore
dendritic cell	3 studies	30% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	20% ± 3%	Explore
mast cell	3 studies	22% ± 4%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	28% ± 8%	Explore
monocyte	3 studies	17% ± 0%	Explore
intestinal crypt stem cell	3 studies	21% ± 2%	Explore
group 3 innate lymphoid cell	3 studies	23% ± 6%	Explore
basal cell	3 studies	36% ± 1%	Explore
pericyte	3 studies	19% ± 3%	Explore
transit amplifying cell	3 studies	26% ± 10%	Explore
adipocyte	3 studies	19% ± 3%	Explore
hepatocyte	3 studies	42% ± 17%	Explore
double negative thymocyte	3 studies	39% ± 5%	Explore
interneuron	3 studies	46% ± 17%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	23% ± 5%	Explore
brain	7 studies	34% ± 17%	Explore
lung	6 studies	22% ± 7%	Explore
liver	6 studies	28% ± 10%	Explore
kidney	4 studies	23% ± 8%	Explore
eye	4 studies	19% ± 6%	Explore
adipose	3 studies	17% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	593.19	1445 / 1445	100%	3.33	183 / 183
liver	100%	752.00	226 / 226	100%	5.58	406 / 406
ovary	100%	510.28	180 / 180	100%	6.35	430 / 430
pancreas	100%	403.56	328 / 328	100%	4.16	178 / 178
stomach	100%	624.69	359 / 359	100%	5.75	286 / 286
uterus	100%	584.18	170 / 170	100%	4.88	459 / 459
lung	100%	775.43	578 / 578	100%	4.48	1154 / 1155
intestine	100%	780.68	966 / 966	100%	6.65	526 / 527
bladder	100%	635.10	21 / 21	100%	5.98	503 / 504
thymus	100%	657.41	653 / 653	100%	3.85	603 / 605
kidney	100%	1103.49	89 / 89	100%	4.46	898 / 901
prostate	100%	674.76	245 / 245	100%	4.70	500 / 502
breast	100%	760.09	459 / 459	100%	4.89	1113 / 1118
brain	99%	517.12	2627 / 2642	100%	3.55	705 / 705
skin	100%	645.77	1808 / 1809	99%	5.02	466 / 472
adrenal gland	100%	822.32	258 / 258	98%	4.06	225 / 230
adipose	100%	775.69	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	7.24	29 / 29
spleen	100%	1554.26	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	4.21	45 / 45
ureter	0%	0	0 / 0	100%	2.40	1 / 1
muscle	100%	601.17	801 / 803	0%	0	0 / 0
blood vessel	100%	624.60	1331 / 1335	0%	0	0 / 0
heart	99%	946.76	853 / 861	0%	0	0 / 0
peripheral blood	94%	598.67	871 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	88%	2.62	70 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0