CIAO2A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	22 studies	29% ± 10%	Explore
macrophage	22 studies	31% ± 12%	Explore
conventional dendritic cell	21 studies	30% ± 12%	Explore
plasmacytoid dendritic cell	17 studies	36% ± 14%	Explore
memory B cell	16 studies	28% ± 9%	Explore
non-classical monocyte	16 studies	29% ± 9%	Explore
classical monocyte	16 studies	29% ± 9%	Explore
monocyte	14 studies	27% ± 9%	Explore
naive B cell	14 studies	28% ± 7%	Explore
regulatory T cell	12 studies	24% ± 6%	Explore
plasma cell	9 studies	30% ± 13%	Explore
dendritic cell	9 studies	34% ± 14%	Explore
CD8-positive, alpha-beta T cell	9 studies	28% ± 9%	Explore
ciliated cell	7 studies	26% ± 7%	Explore
natural killer cell	7 studies	20% ± 4%	Explore
myeloid cell	7 studies	38% ± 12%	Explore
CD4-positive, alpha-beta T cell	7 studies	31% ± 11%	Explore
epithelial cell of proximal tubule	6 studies	20% ± 3%	Explore
precursor B cell	6 studies	34% ± 12%	Explore
epithelial cell	6 studies	42% ± 16%	Explore
gamma-delta T cell	6 studies	22% ± 12%	Explore
T cell	6 studies	22% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	24% ± 7%	Explore
enterocyte	5 studies	20% ± 3%	Explore
abnormal cell	5 studies	23% ± 3%	Explore
plasmablast	4 studies	34% ± 23%	Explore
mononuclear phagocyte	4 studies	29% ± 14%	Explore
kidney loop of Henle epithelial cell	4 studies	18% ± 2%	Explore
transit amplifying cell	4 studies	25% ± 6%	Explore
pro-B cell	4 studies	29% ± 5%	Explore
fibroblast	4 studies	23% ± 4%	Explore
microglial cell	4 studies	24% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	29% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	31% ± 6%	Explore
goblet cell	4 studies	24% ± 9%	Explore
hematopoietic precursor cell	3 studies	26% ± 3%	Explore
basal cell	3 studies	30% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	20% ± 2%	Explore
erythroblast	3 studies	39% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	20% ± 1%	Explore
immature B cell	3 studies	33% ± 13%	Explore
alveolar macrophage	3 studies	26% ± 5%	Explore
endothelial cell	3 studies	29% ± 8%	Explore
T follicular helper cell	3 studies	20% ± 2%	Explore
germinal center B cell	3 studies	31% ± 4%	Explore
exhausted T cell	3 studies	26% ± 7%	Explore
intermediate monocyte	3 studies	42% ± 2%	Explore
GABAergic neuron	3 studies	23% ± 4%	Explore
glutamatergic neuron	3 studies	25% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	22% ± 7%	Explore
double negative thymocyte	3 studies	27% ± 14%	Explore
mucosal invariant T cell	3 studies	18% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	24% ± 7%	Explore
hepatocyte	3 studies	42% ± 24%	Explore
oligodendrocyte precursor cell	3 studies	17% ± 2%	Explore
connective tissue cell	3 studies	23% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	23% ± 4%	Explore
lung	6 studies	23% ± 6%	Explore
brain	6 studies	21% ± 3%	Explore
intestine	6 studies	20% ± 7%	Explore
kidney	4 studies	21% ± 4%	Explore
liver	4 studies	30% ± 20%	Explore
lymph node	4 studies	27% ± 15%	Explore
bone marrow	3 studies	20% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	1181.16	459 / 459	100%	62.85	1118 / 1118
ovary	100%	729.02	180 / 180	100%	59.62	430 / 430
pancreas	100%	1284.32	328 / 328	100%	47.94	178 / 178
esophagus	100%	836.75	1443 / 1445	100%	46.35	183 / 183
lung	100%	1376.71	577 / 578	100%	59.30	1155 / 1155
liver	100%	4101.27	226 / 226	100%	94.47	405 / 406
thymus	100%	2227.42	653 / 653	100%	76.84	603 / 605
kidney	100%	2311.87	89 / 89	100%	56.96	898 / 901
prostate	100%	1821.13	245 / 245	100%	67.46	500 / 502
intestine	100%	1607.19	965 / 966	100%	69.58	525 / 527
brain	99%	787.45	2628 / 2642	100%	48.75	705 / 705
stomach	99%	1420.62	357 / 359	100%	62.67	286 / 286
bladder	100%	912.48	21 / 21	99%	57.89	501 / 504
uterus	100%	779.48	170 / 170	99%	59.84	456 / 459
adrenal gland	100%	2948.37	258 / 258	99%	50.30	227 / 230
skin	99%	1084.73	1792 / 1809	99%	60.67	466 / 472
lymph node	0%	0	0 / 0	100%	89.36	29 / 29
spleen	100%	1950.53	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	51.85	45 / 45
ureter	0%	0	0 / 0	100%	17.99	1 / 1
adipose	100%	1206.66	1203 / 1204	0%	0	0 / 0
muscle	100%	1478.17	802 / 803	0%	0	0 / 0
blood vessel	98%	718.33	1312 / 1335	0%	0	0 / 0
heart	97%	1236.93	839 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	93%	30.82	74 / 80
peripheral blood	89%	1507.37	829 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0097428	Biological process	protein maturation by iron-sulfur cluster transfer
GO_0016226	Biological process	iron-sulfur cluster assembly
GO_0007059	Biological process	chromosome segregation
GO_0106035	Biological process	protein maturation by [4Fe-4S] cluster transfer
GO_0097361	Cellular component	cytosolic [4Fe-4S] assembly targeting complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	CIAO2A
Protein name	Cytosolic iron-sulfur assembly component 2A Cytosolic iron-sulfur assembly component 2A (MIP18 family protein FAM96A) Cytosolic iron-sulfur assembly component 2A (Family with sequence similarity 96, member A, isoform CRA_a)
Synonyms	FAM96A CIA2A hCG_33353
Description	FUNCTION: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins . As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation . May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 . .
Accessions	ENST00000300030.8 [Q9H5X1-1] ENST00000380290.7 [Q9H5X1-2] ENST00000559950.1 Q9H5X1 H0YLH6 ENST00000559705.1 ENST00000557835.5 [Q9H5X1-2] H0YKV4

CIAO2A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review