CEMIP2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	35 studies	36% ± 17%	Explore
natural killer cell	33 studies	33% ± 13%	Explore
B cell	21 studies	27% ± 7%	Explore
T cell	20 studies	25% ± 7%	Explore
CD8-positive, alpha-beta T cell	19 studies	28% ± 10%	Explore
macrophage	18 studies	28% ± 13%	Explore
CD4-positive, alpha-beta T cell	17 studies	27% ± 10%	Explore
mature NK T cell	15 studies	29% ± 12%	Explore
regulatory T cell	15 studies	29% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	40% ± 16%	Explore
vein endothelial cell	10 studies	35% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	39% ± 11%	Explore
naive B cell	9 studies	28% ± 9%	Explore
epithelial cell	9 studies	35% ± 19%	Explore
endothelial cell of vascular tree	9 studies	27% ± 10%	Explore
endothelial cell of lymphatic vessel	8 studies	25% ± 14%	Explore
capillary endothelial cell	8 studies	36% ± 12%	Explore
type I pneumocyte	7 studies	29% ± 9%	Explore
type II pneumocyte	7 studies	25% ± 10%	Explore
myeloid cell	7 studies	29% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	36% ± 7%	Explore
gamma-delta T cell	7 studies	36% ± 20%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	43% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	28% ± 8%	Explore
mucosal invariant T cell	6 studies	24% ± 5%	Explore
endothelial cell of artery	6 studies	24% ± 5%	Explore
glutamatergic neuron	6 studies	36% ± 18%	Explore
monocyte	6 studies	23% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	27% ± 9%	Explore
non-classical monocyte	5 studies	22% ± 4%	Explore
memory B cell	5 studies	23% ± 4%	Explore
dendritic cell	5 studies	21% ± 4%	Explore
lymphocyte	5 studies	42% ± 18%	Explore
Mueller cell	5 studies	49% ± 20%	Explore
astrocyte	5 studies	26% ± 10%	Explore
GABAergic neuron	5 studies	26% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	25% ± 10%	Explore
leukocyte	4 studies	26% ± 11%	Explore
classical monocyte	4 studies	18% ± 1%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	25% ± 5%	Explore
retinal pigment epithelial cell	4 studies	32% ± 10%	Explore
innate lymphoid cell	4 studies	27% ± 17%	Explore
goblet cell	4 studies	31% ± 21%	Explore
fibroblast	4 studies	29% ± 11%	Explore
exhausted T cell	3 studies	33% ± 10%	Explore
endocardial cell	3 studies	56% ± 15%	Explore
mesothelial cell	3 studies	22% ± 5%	Explore
abnormal cell	3 studies	34% ± 9%	Explore
CD4-positive helper T cell	3 studies	31% ± 13%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	32% ± 12%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	24% ± 6%	Explore
pericyte	3 studies	20% ± 5%	Explore
club cell	3 studies	20% ± 4%	Explore
smooth muscle cell	3 studies	23% ± 5%	Explore
T follicular helper cell	3 studies	30% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	22% ± 9%	Explore
neuron	3 studies	35% ± 19%	Explore
interneuron	3 studies	27% ± 9%	Explore
mural cell	3 studies	42% ± 15%	Explore
microglial cell	3 studies	21% ± 6%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	9 studies	22% ± 5%	Explore
peripheral blood	8 studies	22% ± 5%	Explore
brain	6 studies	28% ± 14%	Explore
breast	3 studies	19% ± 4%	Explore
liver	3 studies	33% ± 14%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	100%	4429.14	358 / 359	99%	52.01	284 / 286
lung	100%	14970.52	578 / 578	99%	35.44	1138 / 1155
liver	100%	4841.04	226 / 226	97%	37.64	393 / 406
bladder	100%	3039.81	21 / 21	96%	39.80	486 / 504
intestine	97%	3663.48	934 / 966	99%	53.57	523 / 527
pancreas	98%	2378.09	320 / 328	98%	49.03	174 / 178
breast	100%	4487.80	458 / 459	95%	31.10	1060 / 1118
esophagus	95%	1878.41	1376 / 1445	95%	40.58	174 / 183
thymus	100%	3396.71	652 / 653	89%	18.17	541 / 605
kidney	94%	3096.48	84 / 89	94%	36.34	849 / 901
skin	98%	2987.67	1771 / 1809	90%	24.12	426 / 472
prostate	94%	2121.95	230 / 245	93%	22.55	466 / 502
uterus	91%	1248.35	154 / 170	84%	21.00	387 / 459
brain	87%	1768.77	2311 / 2642	61%	9.27	431 / 705
adrenal gland	94%	1538.53	243 / 258	47%	9.59	107 / 230
adipose	100%	5614.27	1204 / 1204	0%	0	0 / 0
spleen	100%	5323.06	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	13.33	1 / 1
ovary	58%	705.86	105 / 180	42%	5.42	179 / 430
peripheral blood	93%	3678.72	864 / 929	0%	0	0 / 0
blood vessel	85%	1764.25	1136 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	82%	14.74	37 / 45
muscle	78%	1051.84	627 / 803	0%	0	0 / 0
heart	73%	1600.63	630 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	62%	11.40	18 / 29
eye	0%	0	0 / 0	16%	1.60	13 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0