CDC123 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	15 studies	23% ± 7%	Explore
natural killer cell	14 studies	22% ± 6%	Explore
B cell	13 studies	21% ± 6%	Explore
CD8-positive, alpha-beta T cell	13 studies	25% ± 8%	Explore
regulatory T cell	11 studies	23% ± 9%	Explore
CD4-positive, alpha-beta T cell	10 studies	26% ± 11%	Explore
naive B cell	9 studies	19% ± 3%	Explore
memory B cell	8 studies	21% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	19% ± 2%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	20% ± 3%	Explore
plasmacytoid dendritic cell	7 studies	26% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
microglial cell	6 studies	20% ± 6%	Explore
fibroblast	6 studies	23% ± 9%	Explore
epithelial cell	6 studies	35% ± 14%	Explore
macrophage	6 studies	23% ± 4%	Explore
oligodendrocyte precursor cell	6 studies	22% ± 5%	Explore
mucosal invariant T cell	6 studies	16% ± 2%	Explore
T cell	6 studies	19% ± 5%	Explore
hematopoietic precursor cell	5 studies	32% ± 14%	Explore
conventional dendritic cell	5 studies	30% ± 15%	Explore
connective tissue cell	5 studies	20% ± 4%	Explore
pericyte	5 studies	20% ± 3%	Explore
ciliated cell	5 studies	28% ± 10%	Explore
abnormal cell	5 studies	21% ± 6%	Explore
astrocyte	5 studies	21% ± 4%	Explore
goblet cell	5 studies	19% ± 4%	Explore
basal cell	5 studies	34% ± 11%	Explore
oligodendrocyte	5 studies	20% ± 2%	Explore
gamma-delta T cell	5 studies	28% ± 18%	Explore
plasmablast	4 studies	45% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	21% ± 3%	Explore
exhausted T cell	4 studies	25% ± 6%	Explore
precursor B cell	4 studies	24% ± 2%	Explore
smooth muscle cell	4 studies	20% ± 4%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	25% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	33% ± 10%	Explore
GABAergic neuron	4 studies	36% ± 13%	Explore
glutamatergic neuron	4 studies	46% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	23% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	24% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	23% ± 5%	Explore
classical monocyte	3 studies	23% ± 7%	Explore
non-classical monocyte	3 studies	28% ± 5%	Explore
myofibroblast cell	3 studies	17% ± 1%	Explore
capillary endothelial cell	3 studies	16% ± 1%	Explore
myeloid cell	3 studies	22% ± 7%	Explore
endothelial cell of vascular tree	3 studies	18% ± 2%	Explore
dendritic cell	3 studies	46% ± 5%	Explore
granulocyte monocyte progenitor cell	3 studies	33% ± 10%	Explore
hematopoietic stem cell	3 studies	18% ± 2%	Explore
intestinal crypt stem cell	3 studies	21% ± 1%	Explore
transit amplifying cell	3 studies	26% ± 6%	Explore
secretory cell	3 studies	27% ± 14%	Explore
interneuron	3 studies	34% ± 16%	Explore
neuron	3 studies	30% ± 7%	Explore
double negative thymocyte	3 studies	31% ± 15%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	7 studies	21% ± 6%	Explore
brain	6 studies	31% ± 13%	Explore
lung	5 studies	26% ± 12%	Explore
eye	3 studies	18% ± 4%	Explore
intestine	3 studies	21% ± 7%	Explore
liver	3 studies	30% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2215.09	1445 / 1445	100%	65.37	183 / 183
ovary	100%	1458.42	180 / 180	100%	76.16	430 / 430
stomach	100%	1482.72	359 / 359	100%	73.68	286 / 286
uterus	100%	1848.94	170 / 170	100%	74.78	459 / 459
breast	100%	2220.64	459 / 459	100%	80.26	1117 / 1118
intestine	100%	2088.98	966 / 966	100%	80.84	526 / 527
bladder	100%	2004.38	21 / 21	100%	82.48	503 / 504
prostate	100%	1661.52	245 / 245	100%	47.09	501 / 502
liver	100%	1267.89	226 / 226	100%	40.79	405 / 406
brain	100%	1906.36	2635 / 2642	100%	70.80	705 / 705
thymus	100%	1838.76	652 / 653	100%	56.19	604 / 605
lung	100%	1861.89	576 / 578	100%	64.69	1155 / 1155
skin	100%	3018.48	1809 / 1809	99%	60.10	469 / 472
kidney	100%	1625.88	89 / 89	99%	38.08	891 / 901
adrenal gland	100%	2174.72	258 / 258	98%	47.93	226 / 230
pancreas	98%	959.29	320 / 328	99%	53.01	177 / 178
adipose	100%	2268.67	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	103.02	29 / 29
spleen	100%	2631.44	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	62.44	45 / 45
ureter	0%	0	0 / 0	100%	42.70	1 / 1
blood vessel	100%	2271.92	1334 / 1335	0%	0	0 / 0
muscle	100%	1555.44	801 / 803	0%	0	0 / 0
heart	98%	1922.99	848 / 861	0%	0	0 / 0
peripheral blood	97%	4470.36	900 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	96%	40.64	77 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006457	Biological process	protein folding
GO_1905143	Biological process	eukaryotic translation initiation factor 2 complex assembly
GO_0005737	Cellular component	cytoplasm
GO_0044183	Molecular function	protein folding chaperone
GO_0005524	Molecular function	ATP binding
GO_0005515	Molecular function	protein binding
GO_0000287	Molecular function	magnesium ion binding

IV. Literature review

[source]

Gene name	CDC123
Protein name	Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) (Protein D123) (HT-1080) (PZ32)
Synonyms	D123 C10orf7
Description	FUNCTION: ATP-dependent protein-folding chaperone for the eIF2 complex . Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity). .
Accessions	H7BZW7 ENST00000281141.9 ENST00000440613.1 ENST00000429258.6 X6RKY7 ENST00000442050.5 X6RF82 O75794 X6RA30 ENST00000378900.6

CDC123 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review