CCDC91 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
astrocyte	19 studies	38% ± 19%	Explore
macrophage	16 studies	38% ± 20%	Explore
oligodendrocyte	15 studies	35% ± 14%	Explore
endothelial cell	15 studies	32% ± 13%	Explore
B cell	14 studies	27% ± 12%	Explore
microglial cell	14 studies	46% ± 12%	Explore
regulatory T cell	14 studies	23% ± 8%	Explore
oligodendrocyte precursor cell	13 studies	38% ± 14%	Explore
glutamatergic neuron	12 studies	49% ± 25%	Explore
fibroblast	12 studies	32% ± 10%	Explore
natural killer cell	11 studies	25% ± 10%	Explore
GABAergic neuron	11 studies	50% ± 26%	Explore
smooth muscle cell	11 studies	25% ± 8%	Explore
CD4-positive, alpha-beta T cell	10 studies	27% ± 8%	Explore
ciliated cell	10 studies	29% ± 10%	Explore
CD8-positive, alpha-beta T cell	9 studies	24% ± 7%	Explore
adipocyte	9 studies	50% ± 10%	Explore
mast cell	9 studies	27% ± 7%	Explore
T cell	9 studies	32% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	23% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	19% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	26% ± 10%	Explore
epithelial cell	7 studies	39% ± 17%	Explore
mucosal invariant T cell	7 studies	22% ± 8%	Explore
naive B cell	7 studies	19% ± 3%	Explore
dendritic cell	7 studies	41% ± 9%	Explore
pericyte	7 studies	29% ± 7%	Explore
myeloid cell	7 studies	36% ± 11%	Explore
gamma-delta T cell	7 studies	20% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	25% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	18% ± 4%	Explore
interneuron	6 studies	59% ± 26%	Explore
retinal ganglion cell	6 studies	58% ± 15%	Explore
retina horizontal cell	6 studies	30% ± 14%	Explore
retinal cone cell	6 studies	34% ± 12%	Explore
retinal rod cell	6 studies	43% ± 16%	Explore
type I pneumocyte	6 studies	33% ± 9%	Explore
type II pneumocyte	6 studies	35% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 4%	Explore
basal cell	6 studies	33% ± 19%	Explore
neuron	5 studies	40% ± 12%	Explore
amacrine cell	5 studies	45% ± 15%	Explore
cardiac muscle cell	5 studies	42% ± 8%	Explore
mesothelial cell	5 studies	30% ± 7%	Explore
Mueller cell	5 studies	34% ± 14%	Explore
monocyte	5 studies	39% ± 13%	Explore
plasmacytoid dendritic cell	5 studies	22% ± 6%	Explore
mature NK T cell	4 studies	23% ± 9%	Explore
non-classical monocyte	4 studies	22% ± 4%	Explore
granule cell	4 studies	36% ± 12%	Explore
retinal bipolar neuron	4 studies	37% ± 10%	Explore
retinal pigment epithelial cell	4 studies	32% ± 17%	Explore
lymphocyte	4 studies	42% ± 18%	Explore
OFF-bipolar cell	4 studies	43% ± 13%	Explore
ON-bipolar cell	4 studies	44% ± 14%	Explore
endothelial cell of lymphatic vessel	4 studies	21% ± 3%	Explore
abnormal cell	4 studies	19% ± 4%	Explore
leukocyte	4 studies	46% ± 19%	Explore
club cell	4 studies	32% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	17% ± 2%	Explore
memory B cell	4 studies	17% ± 0%	Explore
conventional dendritic cell	3 studies	29% ± 12%	Explore
GABAergic interneuron	3 studies	50% ± 8%	Explore
glial cell	3 studies	23% ± 4%	Explore
progenitor cell	3 studies	22% ± 4%	Explore
precursor B cell	3 studies	20% ± 1%	Explore
plasma cell	3 studies	31% ± 4%	Explore
mononuclear phagocyte	3 studies	33% ± 9%	Explore
GABAergic amacrine cell	3 studies	53% ± 11%	Explore
glycinergic amacrine cell	3 studies	42% ± 4%	Explore
rod bipolar cell	3 studies	45% ± 16%	Explore
hepatocyte	3 studies	60% ± 16%	Explore
muscle cell	3 studies	34% ± 19%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	21% ± 7%	Explore
ependymal cell	3 studies	52% ± 14%	Explore
alveolar macrophage	3 studies	52% ± 11%	Explore
respiratory goblet cell	3 studies	33% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	22% ± 8%	Explore
goblet cell	3 studies	36% ± 24%	Explore
mucus secreting cell	3 studies	35% ± 10%	Explore
innate lymphoid cell	3 studies	26% ± 13%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	17 studies	42% ± 21%	Explore
eye	8 studies	39% ± 15%	Explore
lung	7 studies	28% ± 9%	Explore
heart	4 studies	34% ± 4%	Explore
liver	4 studies	27% ± 8%	Explore
peripheral blood	3 studies	23% ± 3%	Explore
adipose	3 studies	37% ± 11%	Explore
kidney	3 studies	25% ± 5%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	1194.00	245 / 245	100%	10.52	501 / 502
ovary	100%	1325.86	180 / 180	100%	9.22	429 / 430
breast	100%	1499.19	459 / 459	100%	15.80	1115 / 1118
thymus	100%	1406.29	653 / 653	100%	15.38	602 / 605
pancreas	100%	1041.83	328 / 328	99%	10.40	177 / 178
kidney	100%	1235.91	89 / 89	99%	16.73	895 / 901
lung	100%	1114.01	576 / 578	100%	14.32	1150 / 1155
uterus	100%	1379.48	170 / 170	99%	10.46	454 / 459
esophagus	100%	1359.85	1445 / 1445	99%	14.14	181 / 183
adrenal gland	100%	1536.91	258 / 258	99%	13.83	227 / 230
brain	100%	1723.61	2641 / 2642	98%	12.01	694 / 705
bladder	100%	1702.57	21 / 21	98%	9.74	494 / 504
liver	100%	654.77	226 / 226	97%	5.90	394 / 406
stomach	100%	1045.82	359 / 359	96%	8.10	275 / 286
intestine	100%	1411.67	966 / 966	95%	8.42	503 / 527
skin	100%	1061.39	1808 / 1809	92%	9.87	434 / 472
lymph node	0%	0	0 / 0	100%	7.89	29 / 29
muscle	100%	1511.46	803 / 803	0%	0	0 / 0
spleen	100%	1074.39	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	11.09	45 / 45
ureter	0%	0	0 / 0	100%	2.17	1 / 1
adipose	100%	1340.23	1203 / 1204	0%	0	0 / 0
blood vessel	100%	1545.57	1333 / 1335	0%	0	0 / 0
heart	96%	1379.56	826 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	70%	4.55	56 / 80
peripheral blood	57%	412.83	533 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0