CAPNS1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	33 studies	33% ± 13%	Explore
macrophage	28 studies	26% ± 10%	Explore
classical monocyte	26 studies	40% ± 17%	Explore
non-classical monocyte	22 studies	42% ± 18%	Explore
conventional dendritic cell	20 studies	31% ± 21%	Explore
natural killer cell	19 studies	23% ± 10%	Explore
fibroblast	19 studies	24% ± 11%	Explore
monocyte	18 studies	32% ± 9%	Explore
pericyte	17 studies	24% ± 8%	Explore
endothelial cell of lymphatic vessel	16 studies	34% ± 11%	Explore
ciliated cell	14 studies	39% ± 19%	Explore
epithelial cell	14 studies	35% ± 20%	Explore
smooth muscle cell	13 studies	25% ± 6%	Explore
capillary endothelial cell	12 studies	25% ± 5%	Explore
dendritic cell	11 studies	39% ± 25%	Explore
vein endothelial cell	11 studies	31% ± 8%	Explore
plasmacytoid dendritic cell	10 studies	24% ± 9%	Explore
endothelial cell of artery	10 studies	31% ± 9%	Explore
basal cell	9 studies	41% ± 20%	Explore
myeloid cell	9 studies	38% ± 22%	Explore
endothelial cell of vascular tree	9 studies	27% ± 9%	Explore
type I pneumocyte	8 studies	35% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	31% ± 13%	Explore
B cell	7 studies	25% ± 7%	Explore
goblet cell	7 studies	34% ± 11%	Explore
T cell	6 studies	19% ± 3%	Explore
alveolar macrophage	6 studies	23% ± 4%	Explore
mast cell	6 studies	26% ± 5%	Explore
respiratory goblet cell	6 studies	34% ± 18%	Explore
secretory cell	6 studies	39% ± 18%	Explore
connective tissue cell	6 studies	21% ± 4%	Explore
neuron	6 studies	28% ± 15%	Explore
type II pneumocyte	5 studies	26% ± 14%	Explore
club cell	5 studies	34% ± 15%	Explore
platelet	5 studies	27% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	25% ± 8%	Explore
CD4-positive, alpha-beta T cell	5 studies	23% ± 8%	Explore
CD8-positive, alpha-beta T cell	5 studies	27% ± 14%	Explore
hematopoietic precursor cell	5 studies	43% ± 17%	Explore
mature NK T cell	5 studies	23% ± 10%	Explore
enterocyte	5 studies	25% ± 7%	Explore
squamous epithelial cell	4 studies	49% ± 20%	Explore
leukocyte	4 studies	23% ± 4%	Explore
mononuclear phagocyte	4 studies	31% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	35% ± 9%	Explore
plasmablast	4 studies	34% ± 19%	Explore
mesothelial cell	4 studies	27% ± 13%	Explore
retinal ganglion cell	4 studies	73% ± 21%	Explore
myofibroblast cell	4 studies	23% ± 5%	Explore
brush cell	4 studies	25% ± 13%	Explore
abnormal cell	4 studies	21% ± 6%	Explore
intermediate monocyte	4 studies	51% ± 23%	Explore
enteroendocrine cell	4 studies	34% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	26% ± 9%	Explore
gamma-delta T cell	4 studies	28% ± 12%	Explore
ionocyte	3 studies	36% ± 6%	Explore
pancreatic A cell	3 studies	40% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	19% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	30% ± 8%	Explore
glomerular endothelial cell	3 studies	29% ± 4%	Explore
transit amplifying cell	3 studies	22% ± 6%	Explore
kidney loop of Henle epithelial cell	3 studies	25% ± 6%	Explore
lymphocyte	3 studies	33% ± 12%	Explore
megakaryocyte	3 studies	26% ± 6%	Explore
erythroblast	3 studies	42% ± 25%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	19% ± 1%	Explore
pancreatic ductal cell	3 studies	40% ± 13%	Explore
granulocyte monocyte progenitor cell	3 studies	24% ± 7%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	42% ± 18%	Explore
neutrophil	3 studies	22% ± 3%	Explore
regulatory T cell	3 studies	18% ± 1%	Explore
hematopoietic stem cell	3 studies	30% ± 17%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	13 studies	31% ± 17%	Explore
peripheral blood	13 studies	28% ± 14%	Explore
intestine	7 studies	23% ± 7%	Explore
bone marrow	4 studies	27% ± 13%	Explore
uterus	4 studies	34% ± 20%	Explore
liver	4 studies	22% ± 9%	Explore
pancreas	3 studies	35% ± 5%	Explore
kidney	3 studies	23% ± 6%	Explore
eye	3 studies	19% ± 1%	Explore
brain	3 studies	29% ± 0%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	16663.20	258 / 258	100%	357.55	230 / 230
esophagus	100%	22553.98	1445 / 1445	100%	358.76	183 / 183
ovary	100%	12791.89	180 / 180	100%	494.29	430 / 430
thymus	100%	17369.48	653 / 653	100%	440.38	605 / 605
uterus	100%	15425.84	170 / 170	100%	471.83	459 / 459
skin	100%	13410.22	1808 / 1809	100%	429.89	472 / 472
kidney	100%	20553.84	89 / 89	100%	396.76	900 / 901
brain	100%	12773.40	2636 / 2642	100%	286.92	705 / 705
intestine	100%	17036.86	966 / 966	100%	425.46	525 / 527
prostate	100%	17143.43	245 / 245	100%	478.43	500 / 502
stomach	100%	12098.06	359 / 359	99%	364.55	284 / 286
breast	100%	19165.05	459 / 459	99%	426.79	1108 / 1118
bladder	100%	17240.71	21 / 21	99%	449.28	499 / 504
lung	100%	20406.13	578 / 578	99%	383.56	1142 / 1155
liver	99%	6542.95	223 / 226	100%	231.90	406 / 406
pancreas	97%	6639.91	319 / 328	99%	425.01	176 / 178
adipose	100%	21010.38	1204 / 1204	0%	0	0 / 0
blood vessel	100%	19773.47	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	511.59	80 / 80
lymph node	0%	0	0 / 0	100%	339.77	29 / 29
muscle	100%	14679.69	803 / 803	0%	0	0 / 0
spleen	100%	16806.02	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	471.32	45 / 45
ureter	0%	0	0 / 0	100%	364.64	1 / 1
heart	100%	17421.75	859 / 861	0%	0	0 / 0
peripheral blood	100%	15865.26	926 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0016241	Biological process	regulation of macroautophagy
GO_0006508	Biological process	proteolysis
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0110158	Cellular component	calpain complex
GO_0016020	Cellular component	membrane
GO_0004198	Molecular function	calcium-dependent cysteine-type endopeptidase activity
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CAPNS1
Protein name	Calpain small subunit 1 Calpain small subunit 1 (Epididymis secretory sperm binding protein) Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)
Synonyms	CAPNS CAPN4
Description	FUNCTION: Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development (By similarity). .
Accessions	ENST00000590211.5 K7EKD8 ENST00000628018.2 U3KQE2 K7ELJ7 ENST00000586963.1 K7ES78 K7EMQ1 ENST00000628306.2 ENST00000586851.5 ENST00000590049.5 ENST00000591041.5 ENST00000592354.5 ENST00000629983.2 ENST00000587718.5 K7EIV0 K7EM73 A0A075B7C0 P04632 ENST00000588780.5 ENST00000246533.8 ENST00000588815.5 ENST00000590874.5 ENST00000592483.5 A0A0C4DGQ5 S4R3F9 U3KPR7 ENST00000589146.5

CAPNS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review