ARL4A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell of lymphatic vessel	27 studies	59% ± 21%	Explore
endothelial cell	24 studies	36% ± 13%	Explore
B cell	22 studies	25% ± 9%	Explore
non-classical monocyte	20 studies	42% ± 14%	Explore
classical monocyte	20 studies	32% ± 10%	Explore
macrophage	15 studies	28% ± 11%	Explore
conventional dendritic cell	14 studies	28% ± 14%	Explore
basal cell	13 studies	27% ± 10%	Explore
ciliated cell	13 studies	30% ± 17%	Explore
CD4-positive, alpha-beta T cell	13 studies	24% ± 8%	Explore
vein endothelial cell	13 studies	34% ± 10%	Explore
monocyte	12 studies	27% ± 9%	Explore
naive B cell	10 studies	31% ± 10%	Explore
memory B cell	10 studies	30% ± 7%	Explore
endothelial cell of vascular tree	10 studies	31% ± 12%	Explore
T cell	9 studies	19% ± 5%	Explore
natural killer cell	9 studies	21% ± 5%	Explore
endothelial cell of artery	8 studies	25% ± 7%	Explore
gamma-delta T cell	8 studies	26% ± 9%	Explore
leukocyte	7 studies	24% ± 9%	Explore
dendritic cell	7 studies	27% ± 9%	Explore
mucosal invariant T cell	7 studies	28% ± 8%	Explore
epithelial cell	7 studies	41% ± 15%	Explore
erythrocyte	7 studies	32% ± 16%	Explore
regulatory T cell	7 studies	23% ± 7%	Explore
alveolar macrophage	6 studies	39% ± 15%	Explore
mast cell	6 studies	25% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	23% ± 8%	Explore
enterocyte	6 studies	40% ± 17%	Explore
mononuclear phagocyte	5 studies	31% ± 14%	Explore
CD8-positive, alpha-beta T cell	5 studies	23% ± 5%	Explore
fibroblast	5 studies	19% ± 4%	Explore
innate lymphoid cell	5 studies	29% ± 8%	Explore
myeloid cell	5 studies	32% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	26% ± 7%	Explore
oligodendrocyte precursor cell	5 studies	26% ± 9%	Explore
ionocyte	4 studies	46% ± 9%	Explore
secretory cell	4 studies	18% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	24% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	22% ± 5%	Explore
mesothelial cell	4 studies	36% ± 11%	Explore
intermediate monocyte	4 studies	51% ± 9%	Explore
capillary endothelial cell	4 studies	21% ± 5%	Explore
granulocyte	4 studies	23% ± 2%	Explore
plasmacytoid dendritic cell	4 studies	17% ± 1%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	22% ± 5%	Explore
connective tissue cell	3 studies	17% ± 2%	Explore
erythroblast	3 studies	32% ± 15%	Explore
placental villous trophoblast	3 studies	22% ± 7%	Explore
myofibroblast cell	3 studies	23% ± 4%	Explore
immature B cell	3 studies	26% ± 7%	Explore
CD4-positive helper T cell	3 studies	29% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	29% ± 1%	Explore
glutamatergic neuron	3 studies	26% ± 7%	Explore
goblet cell	3 studies	28% ± 8%	Explore
pericyte	3 studies	18% ± 2%	Explore
T follicular helper cell	3 studies	32% ± 12%	Explore
group 3 innate lymphoid cell	3 studies	43% ± 19%	Explore
keratinocyte	3 studies	27% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	31% ± 5%	Explore
mature NK T cell	3 studies	21% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	11 studies	23% ± 7%	Explore
intestine	8 studies	21% ± 4%	Explore
peripheral blood	7 studies	30% ± 6%	Explore
breast	4 studies	21% ± 6%	Explore
liver	4 studies	26% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2031.24	1440 / 1445	100%	24.34	183 / 183
intestine	100%	1974.54	965 / 966	99%	29.10	523 / 527
uterus	100%	1372.54	170 / 170	98%	22.31	450 / 459
stomach	99%	1140.08	356 / 359	99%	24.28	282 / 286
breast	100%	2562.48	459 / 459	97%	18.99	1080 / 1118
prostate	98%	1326.60	241 / 245	98%	14.06	493 / 502
skin	99%	3466.72	1789 / 1809	98%	22.06	461 / 472
lung	96%	1151.08	554 / 578	100%	25.81	1153 / 1155
thymus	99%	1186.06	646 / 653	97%	11.79	585 / 605
bladder	100%	1280.95	21 / 21	94%	18.74	472 / 504
brain	85%	722.74	2251 / 2642	100%	40.95	702 / 705
kidney	60%	336.79	53 / 89	94%	14.12	844 / 901
adrenal gland	72%	372.06	185 / 258	79%	7.88	181 / 230
liver	54%	335.69	122 / 226	83%	13.01	339 / 406
ovary	57%	381.23	102 / 180	80%	8.02	345 / 430
pancreas	19%	84.67	61 / 328	99%	19.33	176 / 178
adipose	100%	1829.73	1204 / 1204	0%	0	0 / 0
spleen	100%	1254.27	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	5.28	1 / 1
tonsil	0%	0	0 / 0	98%	19.48	44 / 45
heart	80%	534.07	685 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	76%	5.94	22 / 29
blood vessel	72%	613.57	958 / 1335	0%	0	0 / 0
peripheral blood	68%	614.32	635 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	57%	4.22	46 / 80
muscle	33%	204.48	266 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0016192	Biological process	vesicle-mediated transport
GO_0050873	Biological process	brown fat cell differentiation
GO_0006886	Biological process	intracellular protein transport
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005525	Molecular function	GTP binding
GO_0005515	Molecular function	protein binding
GO_0003924	Molecular function	GTPase activity

IV. Literature review

[source]

Gene name	ARL4A
Protein name	ADP ribosylation factor like GTPase 4A ADP-ribosylation factor-like protein 4A
Synonyms	ARL4
Description	FUNCTION: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. .
Accessions	ENST00000396663.2 ENST00000439721.1 ENST00000356797.7 ENST00000396662.5 ENST00000651779.1 C9J7Q9 ENST00000404894.1 P40617 ENST00000396664.2

ARL4A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review