ARAP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	30 studies	26% ± 10%	Explore
CD8-positive, alpha-beta T cell	22 studies	26% ± 9%	Explore
astrocyte	19 studies	50% ± 21%	Explore
T cell	18 studies	28% ± 11%	Explore
oligodendrocyte	16 studies	71% ± 17%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	31% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	27% ± 8%	Explore
non-classical monocyte	13 studies	22% ± 10%	Explore
mature NK T cell	13 studies	25% ± 9%	Explore
oligodendrocyte precursor cell	12 studies	40% ± 18%	Explore
endothelial cell	11 studies	27% ± 11%	Explore
mucosal invariant T cell	11 studies	27% ± 7%	Explore
gamma-delta T cell	11 studies	25% ± 6%	Explore
type I pneumocyte	10 studies	48% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	30% ± 8%	Explore
regulatory T cell	10 studies	21% ± 5%	Explore
B cell	9 studies	25% ± 4%	Explore
CD4-positive, alpha-beta T cell	9 studies	29% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	33% ± 8%	Explore
glutamatergic neuron	9 studies	51% ± 28%	Explore
microglial cell	9 studies	29% ± 13%	Explore
dendritic cell	8 studies	29% ± 8%	Explore
basal cell	7 studies	28% ± 15%	Explore
ciliated cell	7 studies	22% ± 7%	Explore
macrophage	7 studies	38% ± 15%	Explore
GABAergic neuron	6 studies	26% ± 10%	Explore
naive B cell	6 studies	19% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	23% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	19% ± 3%	Explore
club cell	5 studies	28% ± 9%	Explore
T follicular helper cell	5 studies	24% ± 4%	Explore
monocyte	5 studies	28% ± 7%	Explore
type II pneumocyte	5 studies	24% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	20% ± 3%	Explore
neuron	4 studies	37% ± 12%	Explore
epithelial cell	4 studies	46% ± 14%	Explore
lymphocyte	4 studies	51% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	21% ± 5%	Explore
leukocyte	3 studies	41% ± 24%	Explore
classical monocyte	3 studies	22% ± 3%	Explore
exhausted T cell	3 studies	32% ± 10%	Explore
glial cell	3 studies	31% ± 12%	Explore
squamous epithelial cell	3 studies	36% ± 22%	Explore
mesothelial cell	3 studies	32% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	27% ± 5%	Explore
respiratory goblet cell	3 studies	19% ± 4%	Explore
innate lymphoid cell	3 studies	26% ± 1%	Explore
ependymal cell	3 studies	40% ± 27%	Explore
myeloid cell	3 studies	27% ± 4%	Explore
plasmacytoid dendritic cell	3 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	32% ± 12%	Explore
mucus secreting cell	3 studies	20% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	14 studies	47% ± 20%	Explore
lung	9 studies	22% ± 4%	Explore
peripheral blood	5 studies	21% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	6000.71	653 / 653	99%	14.49	598 / 605
brain	97%	3244.85	2575 / 2642	99%	19.51	696 / 705
lung	100%	3131.86	577 / 578	95%	8.48	1102 / 1155
intestine	91%	1311.48	883 / 966	90%	5.64	475 / 527
stomach	86%	832.93	308 / 359	91%	5.74	259 / 286
pancreas	80%	686.93	263 / 328	94%	8.28	168 / 178
kidney	76%	807.55	68 / 89	89%	5.84	804 / 901
esophagus	64%	1367.11	929 / 1445	99%	11.97	181 / 183
uterus	78%	749.89	132 / 170	85%	8.85	391 / 459
breast	76%	767.28	349 / 459	84%	5.17	940 / 1118
prostate	82%	814.37	202 / 245	74%	3.12	373 / 502
bladder	52%	758.81	11 / 21	92%	7.12	465 / 504
skin	72%	3702.00	1304 / 1809	67%	4.04	318 / 472
liver	71%	574.13	161 / 226	41%	2.23	167 / 406
spleen	100%	2770.32	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.36	1 / 1
tonsil	0%	0	0 / 0	98%	12.37	44 / 45
lymph node	0%	0	0 / 0	90%	7.59	26 / 29
ovary	15%	116.34	27 / 180	74%	3.30	318 / 430
adipose	85%	1027.27	1024 / 1204	0%	0	0 / 0
peripheral blood	77%	1733.55	716 / 929	0%	0	0 / 0
adrenal gland	5%	36.45	13 / 258	36%	1.91	82 / 230
eye	0%	0	0 / 0	18%	0.60	14 / 80
heart	15%	101.95	127 / 861	0%	0	0 / 0
blood vessel	14%	122.00	189 / 1335	0%	0	0 / 0
muscle	0%	2.97	4 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007165	Biological process	signal transduction
GO_0005737	Cellular component	cytoplasm
GO_0005547	Molecular function	phosphatidylinositol-3,4,5-trisphosphate binding
GO_0046872	Molecular function	metal ion binding
GO_0005096	Molecular function	GTPase activator activity

IV. Literature review

[source]

Gene name	ARAP2
Protein name	ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (Centaurin-delta-1) (Cnt-d1) (Protein PARX) ARAP2 protein
Synonyms	KIAA0580 CENTD1
Description	FUNCTION: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity). .
Accessions	ENST00000511416.1 D6RC39 D6RAD6 A7E2A5 Q2M2Z8 A0A2X0SFS3 ENST00000303965.9 ENST00000506189.1 Q8WZ64

ARAP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review