ADSS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0044208Biological process'de novo' AMP biosynthetic process
GO_0002376Biological processimmune system process
GO_0046040Biological processIMP metabolic process
GO_0014074Biological processresponse to purine-containing compound
GO_0071257Biological processcellular response to electrical stimulus
GO_0060359Biological processresponse to ammonium ion
GO_0006531Biological processaspartate metabolic process
GO_0006167Biological processAMP biosynthetic process
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005739Cellular componentmitochondrion
GO_0005525Molecular functionGTP binding
GO_0042301Molecular functionphosphate ion binding
GO_0005515Molecular functionprotein binding
GO_0004019Molecular functionadenylosuccinate synthase activity
GO_0000287Molecular functionmagnesium ion binding

IV. Literature review

[source]
Gene nameADSS2
Protein nameAdenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)
SynonymsADSS
DescriptionFUNCTION: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. .

FUNCTION: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. .; FUNCTION: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. .

FUNCTION: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. .

AccessionsA0A024R5Q7
B4E1L0
ENST00000366535.4
P30520