RISC complex assembly

I. Literature review

[source]
NameRISC complex assembly
IDGO_0070922
collection_id

Biological process

Alternative ID

GO:0035087, GO:0035280, GO:0070923

Description

The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing complement complex that mediates gene silencing by small RNA.

Related synonym

RISC assembly, gene silencing by RNA, small RNA loading onto RISC, small RNA loading onto RISC

External URL
Genes