Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 13 studies | 28% ± 10% | |
macrophage | 11 studies | 35% ± 15% | |
oligodendrocyte precursor cell | 10 studies | 28% ± 13% | |
glutamatergic neuron | 9 studies | 39% ± 24% | |
microglial cell | 9 studies | 37% ± 10% | |
astrocyte | 9 studies | 29% ± 11% | |
GABAergic neuron | 8 studies | 39% ± 20% | |
oligodendrocyte | 7 studies | 24% ± 6% | |
myeloid cell | 6 studies | 29% ± 12% | |
endothelial cell of lymphatic vessel | 6 studies | 23% ± 5% | |
fibroblast | 6 studies | 23% ± 4% | |
dendritic cell | 5 studies | 26% ± 6% | |
ciliated cell | 5 studies | 21% ± 8% | |
adipocyte | 5 studies | 21% ± 4% | |
monocyte | 5 studies | 33% ± 10% | |
type I pneumocyte | 5 studies | 27% ± 5% | |
interneuron | 5 studies | 43% ± 23% | |
classical monocyte | 4 studies | 27% ± 8% | |
neuron | 4 studies | 31% ± 12% | |
epithelial cell | 4 studies | 30% ± 14% | |
cardiac muscle cell | 4 studies | 20% ± 3% | |
retinal rod cell | 4 studies | 25% ± 6% | |
club cell | 4 studies | 20% ± 5% | |
smooth muscle cell | 4 studies | 20% ± 3% | |
type II pneumocyte | 4 studies | 19% ± 3% | |
GABAergic interneuron | 3 studies | 23% ± 5% | |
ependymal cell | 3 studies | 34% ± 10% | |
alveolar macrophage | 3 studies | 36% ± 8% | |
lymphocyte | 3 studies | 21% ± 6% | |
goblet cell | 3 studies | 38% ± 24% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3211.45 | 1445 / 1445 | 99% | 14.14 | 182 / 183 |
brain | 100% | 2077.90 | 2634 / 2642 | 100% | 17.44 | 703 / 705 |
prostate | 100% | 3175.06 | 245 / 245 | 99% | 12.48 | 499 / 502 |
lung | 100% | 4341.82 | 578 / 578 | 99% | 15.04 | 1147 / 1155 |
breast | 100% | 3022.65 | 459 / 459 | 99% | 15.34 | 1109 / 1118 |
bladder | 100% | 2986.90 | 21 / 21 | 99% | 12.93 | 498 / 504 |
intestine | 100% | 3063.38 | 966 / 966 | 98% | 10.13 | 519 / 527 |
uterus | 100% | 3474.24 | 170 / 170 | 98% | 12.19 | 452 / 459 |
thymus | 100% | 2238.55 | 653 / 653 | 98% | 10.56 | 595 / 605 |
pancreas | 100% | 1819.77 | 327 / 328 | 98% | 12.41 | 175 / 178 |
stomach | 100% | 2782.12 | 359 / 359 | 96% | 10.43 | 275 / 286 |
skin | 100% | 3929.23 | 1808 / 1809 | 95% | 11.19 | 450 / 472 |
kidney | 100% | 1680.72 | 89 / 89 | 95% | 9.99 | 854 / 901 |
ovary | 100% | 2479.44 | 180 / 180 | 94% | 8.90 | 406 / 430 |
liver | 99% | 1420.07 | 224 / 226 | 82% | 5.81 | 334 / 406 |
adrenal gland | 100% | 1757.43 | 258 / 258 | 67% | 3.83 | 154 / 230 |
adipose | 100% | 3076.36 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2998.26 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2638.23 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5241.34 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.69 | 1 / 1 |
heart | 99% | 2169.88 | 853 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 4531.64 | 911 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 11.42 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 9.60 | 27 / 29 |
eye | 0% | 0 | 0 / 0 | 79% | 6.50 | 63 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0035196 | Biological process | miRNA processing |
GO_0007130 | Biological process | synaptonemal complex assembly |
GO_0006402 | Biological process | mRNA catabolic process |
GO_0090625 | Biological process | siRNA-mediated gene silencing by mRNA destabilization |
GO_0035279 | Biological process | miRNA-mediated gene silencing by mRNA destabilization |
GO_0035278 | Biological process | miRNA-mediated gene silencing by inhibition of translation |
GO_0022604 | Biological process | regulation of cell morphogenesis |
GO_0031054 | Biological process | pre-miRNA processing |
GO_0035194 | Biological process | regulatory ncRNA-mediated post-transcriptional gene silencing |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0008584 | Biological process | male gonad development |
GO_0070922 | Biological process | RISC complex assembly |
GO_0010501 | Biological process | RNA secondary structure unwinding |
GO_0010586 | Biological process | miRNA metabolic process |
GO_0007140 | Biological process | male meiotic nuclear division |
GO_0070578 | Cellular component | RISC-loading complex |
GO_0016020 | Cellular component | membrane |
GO_0036464 | Cellular component | cytoplasmic ribonucleoprotein granule |
GO_0000932 | Cellular component | P-body |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0016442 | Cellular component | RISC complex |
GO_0005634 | Cellular component | nucleus |
GO_0004521 | Molecular function | RNA endonuclease activity |
GO_0003727 | Molecular function | single-stranded RNA binding |
GO_0035198 | Molecular function | miRNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0003725 | Molecular function | double-stranded RNA binding |
Gene name | AGO4 |
Protein name | Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) |
Synonyms | EIF2C4 KIAA1567 |
Description | FUNCTION: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). . |
Accessions | Q9HCK5 ENST00000373210.4 |