establishment of blood-brain barrier

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 16 studies
Group 26 studies
Group 322 studies
Group 418 studies
Group 527 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1NDP-FZD4+LRP5NDP_HUMAN - Ligand-Receptor
2WNT7A-FZD10+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
3WNT7A-FZD1+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
4WNT7A-FZD2+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
5WNT7A-FZD3+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
6WNT7A-FZD4+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
7WNT7A-FZD4+LRP6WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
8WNT7A-FZD5+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
9WNT7A-FZD6+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
10WNT7A-FZD7+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
11WNT7A-FZD8+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
12WNT7A-FZD9+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT

III. Literature review

[source]
Nameestablishment of blood-brain barrier
IDGO_0060856
collection_id

Biological process

Exact synonym

establishment of BBB, establishment of blood/brain barrier

Description

Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.

External URL
Genes