BPGM report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BPGM at tissue level.

III. Associated gene sets

GO_0015671Biological processoxygen transport
GO_0005975Biological processcarbohydrate metabolic process
GO_0060856Biological processestablishment of blood-brain barrier
GO_0048821Biological processerythrocyte development
GO_0042832Biological processdefense response to protozoan
GO_0150076Biological processneuroinflammatory response
GO_0006096Biological processglycolytic process
GO_1901136Biological processcarbohydrate derivative catabolic process
GO_0007585Biological processrespiratory gaseous exchange by respiratory system
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0046538Molecular function2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
GO_0016787Molecular functionhydrolase activity
GO_0005515Molecular functionprotein binding
GO_0004082Molecular functionbisphosphoglycerate mutase activity

IV. Literature review

[source]
Gene nameBPGM
Protein nameBisphosphoglycerate mutase (BPGM) (EC 5.4.2.4) (2,3-bisphosphoglycerate mutase, erythrocyte) (2,3-bisphosphoglycerate synthase) (EC 5.4.2.11) (2,3-diphosphoglycerate mutase) (DPGM) (BPG-dependent PGAM)
Phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4)
Synonyms
DescriptionFUNCTION: Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. .

FUNCTION: Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. .

AccessionsENST00000393132.2
ENST00000418040.5
ENST00000344924.8
ENST00000443095.1
C9JH23
P07738