Molecular function

GO:0008338, GO:0008339, GO:0016908, GO:0016909

ERK1, mitogen activated kinase activity

Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.

ATP:protein phosphotransferase (MAPKK-activated) activity, ERK, ERK2, MAPK, mitogen-activated protein kinase activity